Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Paola Porcedda"'
Autor:
Paola Porcedda, Filomena Mazzei, Barbara Pardini, Simonetta Guarrera, Claudia Giachino, Eugenia Dogliotti, Alessandra Allione, Anna Minoprio, Giuseppe Matullo, Valeria Simonelli, Fulvio Ricceri, Alessia Russo
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Due to the great number of genes involved in DNA repair and the interactions among the pathways responsible for the repair of different types of DNA damage, there is an increasing need for simple and reliable approaches to phenotypically assess DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f30c37d07122c7b30726fbbe6e542a
Autor:
Lisa Accomasso, Marisa Pautasso, Luca Orlando, Claudia Giachino, Alessandro Cignetti, Erica Lantelme, Paola Circosta, Ralph A. Willemsen, Valentina Turinetto, Valentina Minieri, Paola Porcedda
Publikováno v:
Molecular Immunology. 48:1369-1376
Induction of the TCR signaling pathway terminates the expression of RAG genes, and a link between this pathway and their transcriptional control is evident from the recent demonstration of their re-expression if the TCR is subsequently lost or down-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ce8e5c3146027d5dcaa7ff78cbac19
https://doi.org/10.1016/j.molimm.2011.02.015
https://doi.org/10.1016/j.molimm.2011.02.015
Autor:
Claudia Giachino, Giuseppe Matullo, Alessandra Allione, Paola Porcedda, Floriana Voglino, Elisa Cibrario Rocchietti, Annamaria Pezzotti, Silvia Polidoro, Fulvio Ricceri, Lisa Accomasso, Valentina Minieri, Fabio Rosa, Simonetta Guarrera, Luca Orlando, Valentina Turinetto
Publikováno v:
DNA Repair
DNA double-strand breaks (DSB) are the most lethal form of ionizing radiation-induced DNA damage, and failure to repair them results in cell death. In order to see if any associations exist between DNA repair gene polymorphisms and phenotypic profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb553b793fc75db74e4d2c8b2ccec625
Autor:
Bruno Garofalo, Valentina Minieri, Paola Porcedda, Giuseppe Matullo, Alessandra Allione, Claudia Giachino, Simonetta Guarrera, Ada Funaro, Francesca Marcon, Francesca Saini, Andrea Zijno, Valentina Turinetto, Riccardo Crebelli
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 684:98-105
As first task of a comprehensive investigation on DNA repair genotype-phenotype correlations, the suitability of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines (LCLs) as surrogate of cryopreserved peripheral blood mononuclear cells (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea530d898c8420f0fcfe3ad7c6a975ab
https://doi.org/10.1016/j.mrfmmm.2009.12.008
https://doi.org/10.1016/j.mrfmmm.2009.12.008
Autor:
Claudia Giachino, Paola Porcedda, Erica Lantelme, Luca Orlando, Antonio Amoroso, Mario De Marchi, Stefania Mantovani, Valentina Turinetto
Publikováno v:
Molecular Immunology. 45:328-337
V(D)J recombination is a mechanism peculiar to the somatic rearrangement of antigen receptor genes. It requires both expression of the RAG-1 and RAG-2 recombinases and accessibility of the substrate to its recombinase and post-cleavage/DNA repair sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61597b313ce1025b2d424978b4d0ba6b
https://doi.org/10.1016/j.molimm.2007.06.153
https://doi.org/10.1016/j.molimm.2007.06.153
Autor:
Simona Cavalieri, Erica Lantelme, Umberto Ricardi, Luca Orlando, Alfredo Brusco, Paola Porcedda, Dario Gregori, Claudia Giachino, Valentina Turinetto, Antonio Amoroso
Publikováno v:
Cytometry Part A. :508-516
Ataxia telangiectasia (A-T) is a progressive neurodegenerative disease with onset in early childhood, caused by mutations in the ATM (ataxia-telangiectasia mutated) gene. Diagnosis relies on laboratory tests showing high levels of serum alphafetoprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4df185461ea9b12ba6be171a5a162d
https://doi.org/10.1002/cyto.a.20566
https://doi.org/10.1002/cyto.a.20566
Autor:
Guido Forni, Augusto Amici, Piero Musiani, Katia Boggio, Paola Porcedda, Stefania Rovero, E. Di Carlo, Elena Quaglino
Publikováno v:
Gene Therapy. 8:447-452
An assessment was made of the effectiveness of DNA vaccination in prevention of the mammary adenocarcinomas of BALB/c female mice transgenic for the activated rat Her-2/neu oncogene. Atypical hyperplasia is evident in their mammary glands when they a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81440d23adddd2126a3691ff5f209895
https://doi.org/10.1038/sj.gt.3301416
https://doi.org/10.1038/sj.gt.3301416
Autor:
Silvia Saviozzi, Valentina Turinetto, Benjamin Kumpfmueller, Elisa Cibrario Rocchietti, Paola Circosta, Luca Orlando, Yolanda Sanchez-Ripoll, Kim Moorwood, Michael P. Storm, Alessandro Cignetti, Valentina Minieri, Lisa Accomasso, Claudia Giachino, Melanie J. Welham, Paola Porcedda
Publikováno v:
Stem cells (Dayton, Ohio). 30(7)
Phosphorylation of histone H2AX (γH2AX) is known to be the earliest indicator of DNA double-strand breaks. Recently, it has been shown that mouse embryonic stem cells (mESCs) have very high basal levels of γH2AX, even when they have not been expose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8dee437e638f13c30108906eead3e8e
https://pubmed.ncbi.nlm.nih.gov/22628289
https://pubmed.ncbi.nlm.nih.gov/22628289
Autor:
Claudia Giachino, Antonio Amoroso, Valentina Minieri, Mario De Marchi, Lisa Accomasso, Laura Zannini, Erica Lantelme, Domenico Delia, Valentina Turinetto, Paola Porcedda, Luca Orlando
We have previously shown that whereas T-cells from normal individuals undergo accumulation of p53 and apoptosis when treated with the genotoxic agent Actinomycin D (ActD), those from Ataxia Telangiectasia (AT) and Nijmegen Breakage Syndrome (NBS) pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fef2f803aa1d9d85f7755eb76b126e
http://hdl.handle.net/2318/81401
http://hdl.handle.net/2318/81401
