Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Paola Pontrelli"'
Autor:
Alessandra Stasi, Marco Fiorentino, Rossana Franzin, Francesco Staffieri, Sabrina Carparelli, Rosa Losapio, Alberto Crovace, Luca Lacitignola, Maria Teresa Cimmarusti, Francesco Murgolo, Monica Stufano, Cesira Cafiero, Giuseppe Castellano, Fabio Sallustio, Chiara Ferrari, Mario Ribezzi, Nicola Brienza, Annalisa Schirinzi, Francesca Di Serio, Salvatore Grasso, Paola Pontrelli, Cyrille Tupin, Ronald Barbaras, Constance Keyserling-Peyrottes, Antonio Crovace, Loreto Gesualdo
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Sepsis is characterized by a dysregulated immune response and metabolic alterations, including decreased high-density lipoprotein cholesterol (HDL-C) levels. HDL exhibits beneficial properties, such as lipopolysaccharides (LPS) sc
Externí odkaz:
https://doaj.org/article/521b7bba327e480e8ee22b2f999b073d
Autor:
Mariagiovanna Di Chiano, Fabio Sallustio, Daniela Fiocco, Maria Teresa Rocchetti, Giuseppe Spano, Paola Pontrelli, Antonio Moschetta, Loreto Gesualdo, Raffaella Maria Gadaleta, Anna Gallone
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9489 (2024)
Neurodegenerative disorders are the main cause of cognitive and physical disabilities, affect millions of people worldwide, and their incidence is on the rise. Emerging evidence pinpoints a disturbance of the communication of the gut–brain axis, an
Externí odkaz:
https://doaj.org/article/2f826935e6184ccca6f73d4371ad6528
Autor:
Adele Mitrotti, Ighli Di Bari, Marica Giliberti, Rossana Franzin, Francesca Conserva, Anna Chiusolo, Maddalena Gigante, Matteo Accetturo, Cesira Cafiero, Luisa Ricciato, Emma Diletta Stea, Cinzia Forleo, Anna Gallone, Michele Rossini, Marco Fiorentino, Giuseppe Castellano, Paola Pontrelli, Loreto Gesualdo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1436 (2024)
Between 15–20% of patients with end stage renal disease (ESRD) do not know the cause of the primary kidney disease and can develop complications after kidney transplantation. We performed a genetic screening in 300 patients with kidney transplantat
Externí odkaz:
https://doaj.org/article/c60354c3330e4e5582b644f85f0dfb2c
Autor:
Michael Crompton, Joanne K. Ferguson, Raina D. Ramnath, Karen L. Onions, Anna S. Ogier, Monica Gamez, Colin J. Down, Laura Skinner, Kitty H. Wong, Lauren K. Dixon, Judit Sutak, Steven J. Harper, Paola Pontrelli, Loreto Gesualdo, Hiddo L. Heerspink, Robert D. Toto, Gavin I. Welsh, Rebecca R. Foster, Simon C. Satchell, Matthew J. Butler
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
The glomerular endothelial glycocalyx (GEnGlx) forms the first part of the glomerular filtration barrier. Previously, we showed that mineralocorticoid receptor (MR) activation caused GEnGlx damage and albuminuria. In this study, we investigated wheth
Externí odkaz:
https://doaj.org/article/359f2aff3fef4349ad8f0cd82c87577a
Autor:
Dario Troise, Barbara Infante, Silvia Mercuri, Giuseppe Stefano Netti, Elena Ranieri, Loreto Gesualdo, Giovanni Stallone, Paola Pontrelli
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2163 (2023)
Hypoxia activates hypoxia-related signaling pathways controlled by hypoxia-inducible factors (HIFs). HIFs represent a quick and effective detection system involved in the cellular response to insufficient oxygen concentration. Activation of HIF signa
Externí odkaz:
https://doaj.org/article/fb98b5bb72494d3795f5cf41a1533d66
Autor:
Barbara Infante, Francesca Conserva, Paola Pontrelli, Serena Leo, Alessandra Stasi, Marco Fiorentino, Dario Troise, Andrea dello Strologo, Carlo Alfieri, Loreto Gesualdo, Giuseppe Castellano, Giovanni Stallone
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Several insults can lead to acute kidney injury (AKI) in native kidney and transplant patients, with diabetes critically contributing as pivotal risk factor. High glucose per se can disrupt several signaling pathways within the kidney that, if not re
Externí odkaz:
https://doaj.org/article/d836a535a1b047b18d570f6ba9d96993
Autor:
Emma Diletta Stea, Christine Skerka, Matteo Accetturo, Francesco Pesce, Thorsten Wiech, Andrea Hartman, Paola Pontrelli, Francesca Conserva, Giuseppe Castellano, Peter F. Zipfel, Loreto Gesualdo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Atypical hemolytic–uremic syndrome (aHUS) is a severe thrombotic microangiopathy in which kidney involvement is common. aHUS can be due to either genetic or acquired abnormalities, with most abnormalities affecting the alternative complement pathwa
Externí odkaz:
https://doaj.org/article/a8abfc2027b845809ec7ad62bf4efa1b
Autor:
Stefania De Santis, Pasquale Crupi, Laura Piacente, Anna Mestice, Nicola Antonio Colabufo, Loredana Amodio, Paola Pontrelli, Loreto Gesualdo, Antonio Moschetta, Maria Lisa Clodoveo, Maria Felicia Faienza, Filomena Corbo
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Obesity represents an important public health challenge of the twenty first century reaching epidemic proportions worldwide; this is especially true for the pediatric population. In this context, bioactive compounds from foods are crucial to countera
Externí odkaz:
https://doaj.org/article/0193a5cbcf2a4ce5b05e74db68509d4a
Autor:
Rossana Franzin, Alessandra Stasi, Giuseppe De Palma, Angela Picerno, Claudia Curci, Serena Sebastiano, Monica Campioni, Antonella Cicirelli, Alessandro Rizzo, Vito Francesco Di Lorenzo, Paola Pontrelli, Giovanni Battista Pertosa, Giuseppe Castellano, Loreto Gesualdo, Fabio Sallustio
Publikováno v:
Cells, Vol 12, Iss 12, p 1655 (2023)
Cisplatin is one of the most effective chemotherapeutic agents strongly associated with nephrotoxicity. Tubular adult renal progenitor cells (tARPC) can regenerate functional tubules and participate in the repair processes after cisplatin exposition.
Externí odkaz:
https://doaj.org/article/60a746a6f48a4577ad286c5999d2d3cd
Autor:
Marco Fiorentino, Francesca Bagagli, Annamaria Deleonardis, Alessandra Stasi, Rossana Franzin, Francesca Conserva, Barbara Infante, Giovanni Stallone, Paola Pontrelli, Loreto Gesualdo
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1474 (2023)
Kidney transplantation is the first-choice treatment for end-stage renal disease (ESRD). Kidney transplant recipients (KTRs) are at higher risk of experiencing a life-threatening event requiring intensive care unit (ICU) admission, mainly in the late
Externí odkaz:
https://doaj.org/article/65700e6d2b624855a316f4a627984b7b