Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Paola Perotti"'
Autor:
Rosario Pivonello, Atanaska Elenkova, Maria Fleseriu, Richard A. Feelders, Przemyslaw Witek, Yona Greenman, Eliza B. Geer, Paola Perotti, Leonard Saiegh, Fredric Cohen, Giorgio Arnaldi
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundCushing’s syndrome (CS) is associated with numerous comorbidities, including diabetes mellitus (DM). Levoketoconazole, an orally administered ketoconazole stereoisomer, is in clinical trials for the treatment of CS.MethodsSONICS, a prospe
Externí odkaz:
https://doaj.org/article/51ea144865b041e48a68e1b013294000
Autor:
Soraya Puglisi, Paola Perotti, Mattia Barbot, Paolo Cosio, Carla Scaroni, Antonio Stigliano, Pina Lardo, Valentina Morelli, Elisa Polledri, Iacopo Chiodini, Giuseppe Reimondo, Anna Pia, Massimo Terzolo
Publikováno v:
Endocrine Connections, Vol 7, Iss 11, Pp 1227-1235 (2018)
Objective: Metyrapone has been approved for the treatment of patients with Cushing’s syndrome (CS), but only few retrospective clinical studies are available. The aim of our study was the prospective assessment of metyrapone as pre-operative treatm
Externí odkaz:
https://doaj.org/article/f860b31abc614888a22db9cd46dc8cbb
Autor:
Deborah Cosentini, Salvatore Grisanti, Alberto Dalla Volta, Marta Laganà, Chiara Fiorentini, Paola Perotti, Sandra Sigala, Alfredo Berruti
Publikováno v:
Endocrine Connections, Vol 7, Iss 12, Pp E5-E8 (2018)
Immunotherapy is widely used in the treatment of different cancer types, including metastatic melanoma, non-small cell lung cancer, renal cell carcinoma and urothelial cancer. The results of the phase I JAVELIN study failed to demonstrate a substanti
Externí odkaz:
https://doaj.org/article/ea4f1600029a43529728f1ef2ca7aa0d
Autor:
Antonina Germano, Laura Saba, Silvia De Francia, Ida Rapa, Paola Perotti, Alfredo Berruti, Marco Volante, Massimo Terzolo
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196931 (2018)
Mitotane is the reference drug for adrenocortical carcinoma (ACC) and the metabolic activation of the drug is considered as essential for its activity. The aim of this study was to assess the role of CYP11B1 on mitotane action and metabolism in H295R
Externí odkaz:
https://doaj.org/article/639b6df1e4d74c81b4a767a4a1e89076
Autor:
Giuseppe Reimondo, Iacopo Chiodini, Soraya Puglisi, Anna Pia, Valentina Morelli, Darko Kastelan, Salvatore Cannavo, Paola Berchialla, Daniela Giachino, Paola Perotti, Alessandra Cuccurullo, Piero Paccotti, Paolo Beck-Peccoz, Mario De Marchi, Massimo Terzolo
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162437 (2016)
Patients with adrenal incidentalomas (AI) may experience detrimental consequences due to a minimal cortisol excess sustained by adrenal adenoma. SNPs of the glucocorticoid receptor gene (NR3C1) modulate individual sensitivity to glucocorticoids and m
Externí odkaz:
https://doaj.org/article/eb13f684c5b049259215e7ac2beed00c
Autor:
Massimo Terzolo, Salvatore Grisanti, Maria Scatolini, Pasquale Tomaiuolo, Enrico Grosso, Vittoria Basile, Deborah Cosentini, Soraya Puglisi, Marta Lagana, Paola Perotti, Elisa Rossini, Sandra Sigala, Marco Volante, Alfredo Berruti
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e956387fe082f8e887bc780a2159fffb
https://doi.org/10.1530/endoabs.90.rc5.2
https://doi.org/10.1530/endoabs.90.rc5.2
Autor:
Anna Calabrese, Soraya Puglisi, Chiara Borin, Vittoria Basile, Paola Perotti, Anna Pia, Paola Berchialla, Marco Volante, Cristian Fiori, Francesco Porpiglia, Andrea Veltri, Giuseppe Reimondo, Massimo Terzolo
Objective The management of adrenocortical carcinoma (ACC) recurrences remains controversial, and we present herein our experience with postoperative ACC recurrences. Design and methods Retrospective analysis in a single reference center of 106 patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817bc773991b9a9ea6a1f8f0669a7e08
https://hdl.handle.net/2318/1886980
https://hdl.handle.net/2318/1886980
Autor:
Soraya Puglisi, Anna Calabrese, Francesco Ferraù, Maria Antonia Violi, Marta Laganà, Salvatore Grisanti, Filippo Ceccato, Carla Scaroni, Guido Di Dalmazi, Antonio Stigliano, Barbara Altieri, Letizia Canu, Paola Loli, Rosario Pivonello, Emanuela Arvat, Valentina Morelli, Paola Perotti, Vittoria Basile, Paola Berchialla, Sara Urru, Cristian Fiori, Francesco Porpiglia, Alfredo Berruti, Anna Pia, Giuseppe Reimondo, Salvatore Cannavò, Massimo Terzolo
Context Because of the rarity of adrenocortical cancer (ACC), only a few population-based studies are available, and they reported limited details in the characterization of patients and their treatment. Objective To describe in a nationwide cohort t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088e72de9e1c3374cbb0fa44070d85f6
https://hdl.handle.net/11379/574904
https://hdl.handle.net/11379/574904
Autor:
Soraya Puglisi, Deborah Cosentini, Salvatore Grisanti, Vittoria Basile, Marta Lagana, VittorioDomenico Ferarri, Andrea Abate, Anna Calabrese, Elisa Rossini, Paola Perotti, Laura Saba, Anna Pia, Sandra Sigala, Alfredo Berruti, Massimo Terzolo
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acbec75b4e232526c9237d97bc83e645
https://doi.org/10.1530/endoabs.81.oc2.6
https://doi.org/10.1530/endoabs.81.oc2.6
Autor:
Soraya Puglisi, Paola Perotti, Laura Saba, Claudia Giachino, Marco Lo Iacono, Giuseppe Reimondo, Jessica Petiti, Massimo Terzolo
Publikováno v:
Cancers
Cancers, Vol 13, Iss 5255, p 5255 (2021)
Cancers, Vol 13, Iss 5255, p 5255 (2021)
Simple Summary Mitotane is the only approved drug for the treatment of advanced adrenocortical carcinoma and for postoperative adjuvant therapy. It is known that mitotane destroys the adrenal cortex impairing steroidogenesis, although its exact molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c44107678594ebd60a205cfd31ce292
https://pubmed.ncbi.nlm.nih.gov/34771418
https://pubmed.ncbi.nlm.nih.gov/34771418