Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Paola Pavan"'
1
Akademický článek
Ultrasensitive detection of cancer biomarkers by nickel-based isolation of polydisperse extracellular vesicles from bloodResearch in context
Autor: Michela Notarangelo, Chiara Zucal, Angelika Modelska, Isabella Pesce, Giorgina Scarduelli, Cristina Potrich, Lorenzo Lunelli, Cecilia Pederzolli, Paola Pavan, Giancarlo la Marca, Luigi Pasini, Paola Ulivi, Himisha Beltran, Francesca Demichelis, Alessandro Provenzani, Alessandro Quattrone, Vito G. D'Agostino
Publikováno v: EBioMedicine, Vol 43, Iss , Pp 114-126 (2019)
Background: Extracellular vesicles (EVs) are secreted membranous particles intensively studied for their potential cargo of diagnostic markers. Efficient and cost-effective isolation methods need to be established for the reproducible and high-throug
Externí odkaz: https://doaj.org/article/135b60c97b1549db8d2dcbf94f9312ce
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2
Akademický článek
Human platelet lysate in mesenchymal stromal cell expansion according to a GMP grade protocol: a cell factory experience
Autor: Valentina Becherucci, Luisa Piccini, Serena Casamassima, Silvia Bisin, Valentina Gori, Francesca Gentile, Riccardo Ceccantini, Elena De Rienzo, Barbara Bindi, Paola Pavan, Vanessa Cunial, Elisa Allegro, Stefano Ermini, Francesca Brugnolo, Giuseppe Astori, Franco Bambi
Publikováno v: Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2018)
Abstract Background The use of platelet lysate (PL) for the ex-vivo expansion of mesenchymal stromal/stem cells (MSCs) was initially proposed by Doucet et al. in 2005, as an alternative to animal serum. Moreover, regulatory authorities discourage the
Externí odkaz: https://doaj.org/article/0b9e38429b7d48e9915d752e5d075191
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3
Akademický článek
Platelet-Rich Plasma Modulates Gap Junction Functionality and Connexin 43 and 26 Expression During TGF-β1–Induced Fibroblast to Myofibroblast Transition: Clues for Counteracting Fibrosis
Autor: Roberta Squecco, Flaminia Chellini, Eglantina Idrizaj, Alessia Tani, Rachele Garella, Sofia Pancani, Paola Pavan, Franco Bambi, Sandra Zecchi-Orlandini, Chiara Sassoli
Publikováno v: Cells, Vol 9, Iss 5, p 1199 (2020)
Skeletal muscle repair/regeneration may benefit by Platelet-Rich Plasma (PRP) treatment owing to PRP pro-myogenic and anti-fibrotic effects. However, PRP anti-fibrotic action remains controversial. Here, we extended our previous researches on the inh
Externí odkaz: https://doaj.org/article/970feece4e264a92a54270d71040af77
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4
Akademický článek
Platelet-Rich Plasma Prevents In Vitro Transforming Growth Factor-β1-Induced Fibroblast to Myofibroblast Transition: Involvement of Vascular Endothelial Growth Factor (VEGF)-A/VEGF Receptor-1-Mediated Signaling †
Autor: Flaminia Chellini, Alessia Tani, Larissa Vallone, Daniele Nosi, Paola Pavan, Franco Bambi, Sandra Zecchi Orlandini, Chiara Sassoli
Publikováno v: Cells, Vol 7, Iss 9, p 142 (2018)
The antifibrotic potential of platelet-rich plasma (PRP) is controversial. This study examined the effects of PRP on in vitro transforming growth factor (TGF)-β1-induced differentiation of fibroblasts into myofibroblasts, the main drivers of fibrosi
Externí odkaz: https://doaj.org/article/43fe46b6b87a4c74ac4b533934831760
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6
A practical approach for gmp-compliant validation of real-time PCR method for mycoplasma detection in human mesenchymal stromal cells as advanced therapy medicinal product
Autor: Francesca Brugnolo, Franco Bambi, Valentina Gori, B. Bindi, Francesca Gentile, L. Piccini, S. Bisin, Paola Pavan, E. De Rienzo, R. Ceccantini, Stefano Ermini, Valentina Becherucci, V. Cunial, L. Curini, Elisa Allegro
Publikováno v: Biologicals. 73:31-40
Background Manufacturing of human Mesenchymal Stromal Cells as advanced therapy medicinal product (ATMP) for clinical use involves an ex vivo expansion, which leads to a risk of contamination by microbiological agents. Even if manufacturing under Goo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdccd55069d20b9aee03d65045ea67f
https://doi.org/10.1016/j.biologicals.2021.07.006
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10
Platelet-rich plasma affects gap junctional features in myofibroblasts in vitro via vascular endothelial growth factor (VEGF)-A/VEGF receptor
Autor: Chiara Sassoli, Rachele Garella, Flaminia Chellini, Alessia Tani, Paola Pavan, Franco Bambi, Sandra Zecchi‐Orlandini, Roberta Squecco
Publikováno v: Experimental physiologyREFERENCES. 107(2)
What is the central question of this study? It is a challenge to discover effective therapies for fibrosis. Increasing evidence supports the antifibrotic potential of platelet-rich plasma (PRP) as a source of bioactive molecules, such as vascular end
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100160781971603ee62863be05fc32db
https://pubmed.ncbi.nlm.nih.gov/34935228
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