Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Paola Parrella"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/6b62575948ff49e0856b7dd367573af8
Autor:
Sara Ravaioli, Roberta Maltoni, Barbara Pasculli, Paola Parrella, Anna Maria Giudetti, Daniele Vergara, Maria Maddalena Tumedei, Francesca Pirini, Sara Bravaccini
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Androgen receptor (AR) is expressed in 60-70% of breast cancers (BCs) and the availability of anti-AR compounds, currently used for treating prostate cancer, paves the way to tackle specifically AR-positive BC patients. The prognostic and predictive
Externí odkaz:
https://doaj.org/article/b67955f818b24cc7a58287a220eb2ff7
Autor:
Andrea Fontana, Raffaela Barbano, Elisa Dama, Barbara Pasculli, Michelina Rendina, Maria Grazia Morritti, Valentina Melocchi, Marina Castelvetere, Vanna Maria Valori, Sara Ravaioli, Sara Bravaccini, Luigi Ciuffreda, Paolo Graziano, Evaristo Maiello, Massimiliano Copetti, Vito Michele Fazio, Manel Esteller, Fabrizio Bianchi, Paola Parrella
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract While the molecular functions of miR-200 family have been deeply investigated, a role for these miRNAs as breast cancer biomarkers remains largely unexplored. In the attempt to clarify this, we profiled the miR-200 family members expression
Externí odkaz:
https://doaj.org/article/7f115660f6094fd1a43b8c2f4d61692a
Autor:
Nadia Trivieri, Riccardo Pracella, Maria Grazia Cariglia, Concetta Panebianco, Paola Parrella, Alberto Visioli, Fabrizio Giani, Amata Amy Soriano, Chiara Barile, Giuseppe Canistro, Tiziana Pia Latiano, Lucia Dimitri, Francesca Bazzocchi, Dario Cassano, Angelo L. Vescovi, Valerio Pazienza, Elena Binda
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Colorectal cancer (CRC) harboring BRAF V600E mutation exhibits low response to conventional therapy and poorest prognosis. Due to the emerging correlation between gut microbiota and CRC carcinogenesis, we investigated in serrated
Externí odkaz:
https://doaj.org/article/a77a0a281c8c412ca8f2c6c0e1b53cf4
Autor:
Daniela Schwarzenbacher, Christiane Klec, Barbara Pasculli, Stefanie Cerk, Beate Rinner, Michael Karbiener, Cristina Ivan, Raffaela Barbano, Hui Ling, Annika Wulf-Goldenberg, Stefanie Stanzer, Gabriel Rinnerthaler, Herbert Stoeger, Thomas Bauernhofer, Johannes Haybaeck, Gerald Hoefler, Stephan Wenzel Jahn, Paola Parrella, George Adrian Calin, Martin Pichler
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Abstract Background Non-coding RNAs and especially microRNAs have been discovered to act as master regulators of cancer initiation and progression. The aim of our study was to discover and characterize the function of yet functionally uncharacterized
Externí odkaz:
https://doaj.org/article/2752cf158c34450c82e06d6e38fa5e14
Autor:
Sara Bravaccini, Eugenio Fonzi, Michela Tebaldi, Davide Angeli, Giovanni Martinelli, Fabio Nicolini, Paola Parrella, Massimiliano Mazza
Publikováno v:
Cell Transplantation, Vol 30 (2021)
Translational Relevance No prophylactic treatments for COVID-19 have been clearly proven and found. In this pandemic context, cancer patients constitute a particularly fragile population that would benefit the best from such treatments, a present unm
Externí odkaz:
https://doaj.org/article/e5c16058b1bb42d5b7b9d759137e8e9c
Autor:
Brigida Anna Maiorano, Domenica Lorusso, Mauro Francesco Pio Maiorano, Davide Ciardiello, Paola Parrella, Antonio Petracca, Gennaro Cormio, Evaristo Maiello
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3871 (2022)
Ovarian cancer (OC) has a high impact on morbidity and mortality in the female population. Survival is modest after platinum progression. Therefore, the search for new therapeutic strategies is of utmost importance. BRCA mutations and HR-deficiency o
Externí odkaz:
https://doaj.org/article/abe9f8e2323045d3bff9b9f03a3f6b9d
Autor:
Barbara Pasculli, Raffaela Barbano, Andrea Fontana, Tommaso Biagini, Maria Pia Di Viesti, Michelina Rendina, Vanna Maria Valori, Maria Morritti, Sara Bravaccini, Sara Ravaioli, Evaristo Maiello, Paolo Graziano, Roberto Murgo, Massimiliano Copetti, Tommaso Mazza, Vito Michele Fazio, Manel Esteller, Paola Parrella
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
miR-155-5p is a well-known oncogenic microRNA, showing frequent overexpression in human malignancies, including breast cancer. Here, we show that high miR-155-5p levels are associated with unfavorable prognostic factors in two independent breast canc
Externí odkaz:
https://doaj.org/article/112af3529c1a46298fe13b342f1f95e1
Autor:
Carmela Fusco, Grazia Nardella, Bartolomeo Augello, Francesca Boccafoschi, Orazio Palumbo, Luca Fusaro, Angelantonio Notarangelo, Raffaela Barbano, Paola Parrella, Giuseppina Annicchiarico, Carmela De Meco, Lucia Micale, Paolo Graziano, Marco Castori
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5141 (2020)
Transforming growth factor β (TGF-β) superfamily signaling pathways are ubiquitous and essential for several cellular and physiological processes. The overexpression of TGF-β results in excessive fibrosis in multiple human disorders. Among them, s
Externí odkaz:
https://doaj.org/article/4c7d3d3b8b65421cb6f73157dd6d036e
Autor:
Francesco Picardo, Antonella Romanelli, Laura Muinelo-Romay, Tommaso Mazza, Caterina Fusilli, Paola Parrella, Jorge Barbazán, Rafael Lopez-López, Raffaela Barbano, Mariangela De Robertis, Chiara Taffon, Veronica Bordoni, Chiara Agrati, Manuela Costantini, Francesca Ricci, Paolo Graziano, Evaristo Maiello, Lucia Anna Muscarella, Vito Michele Fazio, Maria Luana Poeta
Publikováno v:
Cancers, Vol 11, Iss 10, p 1598 (2019)
Epigenetic modifications of glyco-genes have been documented in different types of cancer and are tightly linked to proliferation, invasiveness, metastasis, and drug resistance. This study aims to investigate the diagnostic, prognostic, and therapy-r
Externí odkaz:
https://doaj.org/article/ef525f06b1a34fbf80a9d6a9b58d7654