Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Paola Nocerino"'
Autor:
Sara Raimondi, Giulia Faravelli, Paola Nocerino, Valentina Mondani, Alma Baruffaldi, Loredana Marchese, Maria Chiara Mimmi, Diana Canetti, Guglielmo Verona, Marianna Caterino, Margherita Ruoppolo, P. Patrizia Mangione, Vittorio Bellotti, Francesca Lavatelli, Sofia Giorgetti
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 11, Pp 484-505 (2023)
Abstract β2‐microglobulin (β2‐m) is a plasma protein derived from physiological shedding of the class I major histocompatibility complex (MHCI), causing human systemic amyloidosis either due to persistently high concentrations of the wild‐typ
Externí odkaz:
https://doaj.org/article/5149cb901be64b8ea5200c5f776cb102
Autor:
James W Opzoomer, Jessica A Timms, Kevin Blighe, Thanos P Mourikis, Nicolas Chapuis, Richard Bekoe, Sedigeh Kareemaghay, Paola Nocerino, Benedetta Apollonio, Alan G Ramsay, Mahvash Tavassoli, Claire Harrison, Francesca Ciccarelli, Peter Parker, Michaela Fontenay, Paul R Barber, James N Arnold, Shahram Kordasti
Publikováno v:
eLife, Vol 10 (2021)
High-dimensional cytometry is an innovative tool for immune monitoring in health and disease, and it has provided novel insight into the underlying biology as well as biomarkers for a variety of diseases. However, the analysis of large multiparametri
Externí odkaz:
https://doaj.org/article/78033dd608be40de9a83b21d8e652c8c
Autor:
Diana Canetti, Francesca Brambilla, Nigel B. Rendell, Paola Nocerino, Janet A. Gilbertson, Dario Di Silvestre, Andrea Bergamaschi, Francesca Lavatelli, Giampaolo Merlini, Julian D. Gillmore, Vittorio Bellotti, Pierluigi Mauri, Graham W. Taylor
Publikováno v:
Molecules, Vol 26, Iss 7, p 1913 (2021)
Amyloidosis is a relatively rare human disease caused by the deposition of abnormal protein fibres in the extracellular space of various tissues, impairing their normal function. Proteomic analysis of patients’ biopsies, developed by Dogan and coll
Externí odkaz:
https://doaj.org/article/c017e28d85fb481d96668e37ce4a88b4
Autor:
Dorota Rowczenio, Nicola A. Botcher, Guglielmo Verona, Paola Nocerino, Graham W. Taylor, Palma Mangione, Philip N. Hawkins, Diana Canetti, Angel Blanco, Janet A. Gilbertson, Vittorio Bellotti, Julian D. Gillmore, Lucia Di Vagno, Nigel B. Rendell
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 58:948-957
Systemic amyloidosis is a serious disease which is caused when normal circulating proteins misfold and aggregate extracellularly as insoluble fibrillary deposits throughout the body. This commonly results in cardiac, renal and neurological damage. Th
Autor:
Benedetta Costantini, Lynne M. Mitchell, Claudia Kemper, Voon H Ong, Giuseppina Arbore, Kevin Blighe, Christopher P. Denton, Shahram Kordasti, Trent M. Woodruff, Dennis E. Hourcade, Leo Placais, Richard Ellis, Paola Nocerino, Susanne Heck, David Abraham
Publikováno v:
Cellular and Molecular Immunology
Arbore, G, Ong, V H, Costantini, B, Denton, C P, Abraham, D, Placais, L, Blighe, K, Mitchell, L, Ellis, R, Heck, S, Nocerino, P, Woodruff, T M, Kordasti, S, Kemper, C & Hourcade, D E 2020, ' Deep phenotyping detects a pathological CD4+ T-cell complosome signature in systemic sclerosis ', Cellular and Molecular Immunology, vol. 17, no. 9, pp. 1010-1013 . https://doi.org/10.1038/s41423-019-0360-8
Arbore, G, Ong, V H, Costantini, B, Denton, C P, Abraham, D, Placais, L, Blighe, K, Mitchell, L, Ellis, R, Heck, S, Nocerino, P, Woodruff, T M, Kordasti, S, Kemper, C & Hourcade, D E 2020, ' Deep phenotyping detects a pathological CD4+ T-cell complosome signature in systemic sclerosis ', Cellular and Molecular Immunology, vol. 17, no. 9, pp. 1010-1013 . https://doi.org/10.1038/s41423-019-0360-8
Autor:
Guglielmo Verona, Paola Nocerino, Angel Blanco, Vittorio Bellotti, Loredana Marchese, Julian D. Gillmore, Dorota Rowczenio, Philip N. Hawkins, Nicola A. Botcher, Per Westermark, Alessandra Morelli, Janet A. Gilbertson, Palma Mangione, Alessandra Corazza, Graham W. Taylor, Diana Canetti, Sofia Giorgetti, Nigel B. Rendell
Publikováno v:
The Journal of pathology. 255(3)
Apolipoprotein A-IV amyloidosis is an uncommon form of the disease normally resulting in renal and cardiac dysfunction. ApoA-IV amyloidosis was identified in 16 patients attending the National Amyloidosis Centre and in eight clinical samples received
Autor:
Benedetta Apollonio, Richard Bekoe, Sedigeh Kareemaghay, Francesca D. Ciccarelli, Paul R. Barber, Thanos P. Mourikis, Claire Harrison, Paola Nocerino, Jessica A Timms, James N. Arnold, Alan G. Ramsay, Mahvash Tavassoli, James W. Opzoomer, Kevin Blighe, Nicolas Chapuis, Peter J. Parker, Michaela Fontenay, Shahram Kordasti
Publikováno v:
Opzoomer, J W, Timms, J A, Blighe, K, Mourikis, T P, Chapuis, N, Bekoe, R, Kareemaghay, S, Nocerino, P, Apollonio, B, Ramsay, A G, Tavassoli, M, Harrison, C, Ciccarelli, F D, Parker, P, Fontenay, M, Barber, P R, Arnold, J N & Kordasti, S 2021, ' ImmunoCluster provides a computational framework for the non-specialist to profile high-dimensional cytometry data ', eLife, vol. 10, e62915 . https://doi.org/10.7554/eLife.62915
eLife, Vol 10 (2021)
eLife
eLife, Vol 10 (2021)
eLife
High-dimensional cytometry is an innovative tool for immune monitoring in health and disease, and it has provided novel insight into the underlying biology as well as biomarkers for a variety of diseases. However, the analysis of large multiparametri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1caed4177a325b866bb97513d1aadc2c
https://kclpure.kcl.ac.uk/en/publications/9003675c-8d24-4ac4-b33f-f41f3d0c1315
https://kclpure.kcl.ac.uk/en/publications/9003675c-8d24-4ac4-b33f-f41f3d0c1315
Autor:
Paola Nocerino, Iain J. Uings, Ryan P. Bingham, Alessandra Corazza, Diana Canetti, Guglielmo Verona, Palma Mangione, Christopher A. Waudby, John Christodoulou, Vittorio Bellotti, Mark B. Pepys, Graham W. Taylor
Publikováno v:
Journal of Medicinal Chemistry
The wild type protein, transthyretin (TTR), and over 120 genetic TTR variants are amyloidogenic and cause, respectively, sporadic and hereditary systemic TTR amyloidosis. The homotetrameric TTR contains two identical thyroxine binding pockets, occupa
Autor:
Benedetta Apollonio, Michaela Fontenay, James N. Arnold, Sedigeh Kareemaghay, Peter J. Parker, Jessica A Timms, Shahram Kordasti, Francesca D. Ciccarelli, Paola Nocerino, Mahvash Tavassoli, Thanos P. Mourikis, Paul R. Barber, Claire Harrison, Nicolas Chapuis, Richard Bekoe, Kevin Blighe, James W. Opzoomer, Alan G. Ramsay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61f8e9d79380a3a4b5a0e14d3c2cff96
https://doi.org/10.7554/elife.62915.sa2
https://doi.org/10.7554/elife.62915.sa2
Autor:
Janet A. Gilbertson, Vittorio Bellotti, Julian D. Gillmore, Francesca Lavatelli, Diana Canetti, Graham W. Taylor, Paola Nocerino, Dario Di Silvestre, Giampaolo Merlini, Andrea Bergamaschi, Pierluigi Mauri, Francesca Brambilla, Nigel B. Rendell
Publikováno v:
Molecules
Molecules, Vol 26, Iss 1913, p 1913 (2021)
Volume 26
Issue 7
Molecules, Vol 26, Iss 1913, p 1913 (2021)
Volume 26
Issue 7
Amyloidosis is a relatively rare human disease caused by the deposition of abnormal protein fibres in the extracellular space of various tissues, impairing their normal function. Proteomic analysis of patients’ biopsies, developed by Dogan and coll