Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Paola Nix"'
Autor:
Tanimul Alam, Hiroki Maruyama, Chun Li, Strahil Iv. Pastuhov, Paola Nix, Michael Bastiani, Naoki Hisamoto, Kunihiro Matsumoto
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The molecular mechanism of axon regeneration after injury is poorly understood. Here the authors show that in C. elegans, the HIF-1 transcription factor induces ectopic synthesis of serotonin in severed ‘non-serotonergic’ neurons and that seroton
Externí odkaz:
https://doaj.org/article/df74211fbd2e45be8c4c87f6e1c01ced
Autor:
Elizabeth Goossen, Karla R. Bowles, Paola Nix, Benjamin B. Roa, Bryan M. Warf, Bradford Coffee, Erin Mundt, Krystal Brown
Publikováno v:
Familial Cancer
A substantial proportion of pathogenic variants associated with an increased risk of hereditary cancer are sequence variants affecting RNA splicing. The classification of these variants can be complex when both non-functional and functional transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a24b81ff5cbd7911397cbcf1c373da
https://doi.org/10.1007/s10689-020-00224-y
https://doi.org/10.1007/s10689-020-00224-y
Publikováno v:
JCO Precision Oncology. :730-735
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49d1d1223ac19a141dcaaa6d165bc216
https://doi.org/10.1200/po.20.00118
https://doi.org/10.1200/po.20.00118
Publikováno v:
JCO precision oncology. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6bceb83935c010c90340975455b3d662
https://pubmed.ncbi.nlm.nih.gov/35050751
https://pubmed.ncbi.nlm.nih.gov/35050751
Publikováno v:
JCO Precision Oncology. :1224-1225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d3ea1138fe5f868bcc8365bbb72b64
https://doi.org/10.1200/po.20.00347
https://doi.org/10.1200/po.20.00347
Autor:
Naoki Hisamoto, Paola Nix, Hiroki Maruyama, Kunihiro Matsumoto, Tanimul Alam, Michael J. Bastiani, Strahil Iv. Pastuhov, Chun Li
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Communications
The molecular mechanisms underlying the ability of axons to regenerate after injury remain poorly understood. Here we show that in Caenorhabditis elegans, axotomy induces ectopic expression of serotonin (5-HT) in axotomized non-serotonergic neurons v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b280aec3b728759d4af8d914215925
https://doaj.org/article/df74211fbd2e45be8c4c87f6e1c01ced
https://doaj.org/article/df74211fbd2e45be8c4c87f6e1c01ced
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 35(34)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dcb0ac8537d29fbb317f29687a17c7
https://pubmed.ncbi.nlm.nih.gov/28981386
https://pubmed.ncbi.nlm.nih.gov/28981386
Autor:
Paola Nix, Linda Hauth, Michael J. Bastiani, Martina Lachnit, Marc Hammarlund, Erik M. Jorgensen
Publikováno v:
The Journal of Neuroscience. 34:629-645
Axons of the mammalian CNS lose the ability to regenerate soon after development due to both an inhibitory CNS environment and the loss of cell-intrinsic factors necessary for regeneration. The complex molecular events required for robust regeneratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3e5b1a3cb07ec8a2524de9a046502f
https://doi.org/10.1523/jneurosci.3859-13.2014
https://doi.org/10.1523/jneurosci.3859-13.2014
Publikováno v:
Farboud, B; Nix, P; Jow, MM; Gladden, JM; & Meyer, BJ. (2013). Molecular antagonism between X-chromosome and autosome signals determines nematode sex. Genes and Development, 27(10), 1159-1178. doi: 10.1101/gad.217026.113. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1qf8t32r
Sex is determined in Caenorhabditis elegans by the ratio of X chromosomes to the sets of autosomes, the X:A signal. A set of genes called X signal elements (XSEs) communicates X-chromosome dose by repressing the masculinizing sex determination switch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2160e1eae356a73bef374ae5440e15ec
https://doi.org/10.1101/gad.217026.113
https://doi.org/10.1101/gad.217026.113
Publikováno v:
Science. 323:802-806
Regeneration of injured neurons can restore function, but most neurons regenerate poorly or not at all. The failure to regenerate in some cases is due to a lack of activation of cell-intrinsic regeneration pathways. These pathways might be targeted f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543500ce5902e37d9b98de05d5c84fdd
https://doi.org/10.1126/science.1165527
https://doi.org/10.1126/science.1165527