Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Paola Nisticò"'
Autor:
Enzo Gallo, Davide Guardiani, Martina Betti, Brindusa Ana Maria Arteni, Simona Di Martino, Sara Baldinelli, Theodora Daralioti, Elisabetta Merenda, Andrea Ascione, Paolo Visca, Edoardo Pescarmona, Marialuisa Lavitrano, Paola Nisticò, Gennaro Ciliberto, Matteo Pallocca
Publikováno v:
Journal of Pathology Informatics, Vol 15, Iss , Pp 100400- (2024)
Purpose: The abundance and distribution of tumor-infiltrating lymphocytes (TILs) as well as that of other components of the tumor microenvironment is of particular importance for predicting response to immunotherapy in lung cancer (LC). We describe h
Externí odkaz:
https://doaj.org/article/8f13267430824393a134ae7a72d1daff
Autor:
Ornella Franzese, Belinda Palermo, Giuseppe Frisullo, Mariangela Panetta, Giulia Campo, Daniel D’Andrea, Isabella Sperduti, Riccardo Taje, Paolo Visca, Paola Nisticò
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Improving cancer immunotherapy efficacy hinges on identifying key T-cell populations critical for tumor control and response to Immune Checkpoint Blockade (ICB). We have recently reported that while the co-expression of PD-1 and CD28 is associated wi
Externí odkaz:
https://doaj.org/article/4a3fe000f0ec40e5ac1a176751a5d0fd
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-21 (2023)
Abstract In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeti
Externí odkaz:
https://doaj.org/article/e09281ff7fdb4567b0b0bb9f575a4fa5
Autor:
Francesca Di Modugno, Anna Di Carlo, Sheila Spada, Belinda Palermo, Lorenzo D'Ambrosio, Daniel D'Andrea, Gaia Morello, Beatrice Belmonte, Isabella Sperduti, Vittoria Balzano, Enzo Gallo, Roberta Melchionna, Mariangela Panetta, Giulia Campo, Francesca De Nicola, Frauke Goeman, Barbara Antoniani, Silvia Carpano, Gianmaria Frigè, Sarah Warren, Filippo Gallina, Diether Lambrechts, Jieyi Xiong, Benjamin G. Vincent, Nathan Wheeler, Dante S. Bortone, Federico Cappuzzo, Francesco Facciolo, Claudio Tripodo, Paolo Visca, Paola Nisticò
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105003- (2024)
Summary: Background: Tertiary Lymphoid Structures (TLS) correlate with positive outcomes in patients with NSCLC and the efficacy of immune checkpoint blockade (ICB) in cancer. The actin regulatory protein hMENA undergoes tissue-specific splicing, pro
Externí odkaz:
https://doaj.org/article/5fd739eb5c1748ce8a0ed4de3fe1985a
Autor:
Belinda Palermo, Ornella Franzese, Giuseppe Frisullo, Lorenzo D’Ambrosio, Mariangela Panetta, Giulia Campo, Daniel D’Andrea, Isabella Sperduti, Francesca De Nicola, Frauke Goeman, Filippo Gallina, Paolo Visca, Francesco Facciolo, Paola Nisticò
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-26 (2023)
Abstract Background Immune checkpoint blockade (ICB) has significantly prolonged survival of non-small cell lung cancer (NSCLC) patients, although most patients develop mechanisms of resistance. Recently single-cell RNA-sequencing (scRNA-Seq) reveale
Externí odkaz:
https://doaj.org/article/571ea82633d4428bb111cb168f3d2393
Autor:
Belinda Palermo, Marta Bottero, Mariangela Panetta, Adriana Faiella, Isabella Sperduti, Serena Masi, Giuseppe Frisullo, Maria Laura Foddai, Iole Cordone, Paola Nisticò, Giuseppe Sanguineti
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTThe impact of radiotherapy (RT) on immune cell status in prostate cancer (PCa) is only partially determined. The aim of this study was to assess the effect of different RT strategies on peripheral B, T, and Natural killer (NK) lymphocytes at
Externí odkaz:
https://doaj.org/article/e599e4d421d94547bf7d4c518a65f5cb
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Profiling the T-Cell Receptor (TCR) repertoire is establishing as a potent approach to investigate autologous and treatment-induced antitumor immune response. Technical and computational breakthroughs, including high throughput next-generati
Externí odkaz:
https://doaj.org/article/829ea4156d994194b368ba84cb9bcea9
Autor:
Sarah Warren, Paola Nisticò, Federico Cappuzzo, Federica Marchesi, Isabella Sperduti, Silvia Carpano, Francesca De Nicola, Frauke Goeman, Lorenzo D'Ambrosio, Vanesa Gregorc, Claudio Tripodo, Vincenzo Russo, Paolo Visca, Francesca Paolini, Paola Trono, Annalisa Tocci, Belinda Palermo, Anna Di Carlo, Daniel D'Andrea, Francesca Di Modugno, Giacomo Corleone, Mariangela Panetta, Silvia Baldari, Paolo Zucali
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Understanding how cancer signaling pathways promote an immunosuppressive program which sustains acquired or primary resistance to immune checkpoint blockade (ICB) is a crucial step in improving immunotherapy efficacy. Among the pathways th
Externí odkaz:
https://doaj.org/article/fd3fa3f807bf4ff6ad2b89290cb99193
Autor:
Federica Moschella, Carla Buccione, Irene Ruspantini, Luciano Castiello, Andrea Rozo Gonzalez, Floriana Iacobone, Virginia Ferraresi, Belinda Palermo, Paola Nisticò, Filippo Belardelli, Enrico Proietti, Iole Macchia, Francesca Urbani
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionDespite the recent approval of several therapies in the adjuvant setting of melanoma, tumor relapse still occurs in a significant number of completely resected stage III-IV patients. In this context, the use of cancer vaccines is still re
Externí odkaz:
https://doaj.org/article/a77e723dd2b3429a807eff3234074e99
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 79-85 (2021)
To date SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), a member of the Coronaviridae family, has infected more than 40 million people worldwide. A second wave of SARS-CoV-2 infection is aggressively surging. The clinical worsening of S
Externí odkaz:
https://doaj.org/article/759f466651eb4cc1b63a15d6502d6ad1