Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Paola Minosi"'
Autor:
Lorenza Marinaccio, Gokhan Zengin, Stefano Pieretti, Paola Minosi, Edina Szucs, Sandor Benyhe, Ettore Novellino, Domiziana Masci, Azzurra Stefanucci, Adriano Mollica
Publikováno v:
Food Chemistry: X, Vol 18, Iss , Pp 100640- (2023)
Rubiscolin-6 (amino acid sequence: YPLDLF) is a selective δ-opioid receptor peptide isolated from spinach Rubisco. Its synthetic analogue, peptide YPMDIV is the most potent described so far for its increased opioid activity, thus in this work it was
Externí odkaz:
https://doaj.org/article/8ae8bcac785b43ffa3acc6337d66acbf
Autor:
Azzurra Stefanucci, Marilisa Pia Dimmito, Giancarlo Tenore, Stefano Pieretti, Paola Minosi, Gokhan Zengin, Chiara Sturaro, Girolamo Calò, Ettore Novellino, Angelo Cichelli, Adriano Mollica
Publikováno v:
Journal of Functional Foods, Vol 73, Iss , Pp 104154- (2020)
The aim of this work is to investigate the pharmacokinetic properties, antinociceptive and antioxidant activities of rubiscolin-6, soymorphin-6 and their C-terminal amides; The four peptides were synthesized following Fmoc-SPPS strategy to give the f
Externí odkaz:
https://doaj.org/article/ad197431e5a64edfa56ab55cb5f18b75
Autor:
Azzurra Stefanucci, Giancarlo Tenore, Stefano Pieretti, Paola Minosi, Gokhan Zengin, Chiara Sturaro, Girolamo Calò, Ettore Novellino, Angelo Cichelli, Adriano Mollica
Publikováno v:
Biology and Life Sciences Forum, Vol 6, Iss 1, p 50 (2021)
This study aims to investigate the pharmacokinetic properties, antinociceptive, and antioxidant activities of rubiscolin-6, soymorphin-6, and their C-terminal amides. Rubiscolin-6 and soymorphin-6 are two exhorphins derived from spinach and soybean,
Externí odkaz:
https://doaj.org/article/ed2efabb001649ac9c7c77475cb31dd4
Autor:
Azzurra Stefanucci, Valeria Iobbi, Alice Della Valle, Giuseppe Scioli, Stefano Pieretti, Paola Minosi, Sako Mirzaie, Ettore Novellino, Adriano Mollica
Publikováno v:
Molecules, Vol 26, Iss 16, p 4767 (2021)
The kappa opioid receptor (KOR) represents an attractive target for the development of drugs as potential antidepressants, anxiolytics and analgesics. A robust computational approach may guarantee a reduction in costs in the initial stages of drug di
Externí odkaz:
https://doaj.org/article/26baa949ab1246b5be864d1c5b3f0890
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 608 (2021)
Glycyrrhiza glabra, commonly known as liquorice, contains several bioactive compounds such as flavonoids, sterols, triterpene, and saponins; among which, glycyrrhizic acid, an oleanane-type saponin, is the most abundant component in liquorice root. D
Externí odkaz:
https://doaj.org/article/522404e754eb4b119fc6bcf425c323a0
Autor:
Tommaso Sciarra, Mario Ciccotti, Paola Aiello, Paola Minosi, Diego Munzi, Cosimo Buccolieri, Ilaria Peluso, Maura Palmery, Florigio Lista
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/7d606743aa8c41f78f674e369e52d0e5
Autor:
Marilisa P. Dimmito, Azzurra Stefanucci, Stefano Pieretti, Paola Minosi, Szabolcs Dvorácskó, Csaba Tömböly, Gokhan Zengin, Adriano Mollica
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 492 (2019)
The endocannabinoid system represents an integrated neuronal network involved in the control of several organisms’ functions, such as feeding behavior. A series of hybrids of 5-(4-chlorophenyl)-1-(2,4-dichloro-phenyl)-4-methyl-N-(piperidin-1-yl)-1H
Externí odkaz:
https://doaj.org/article/1d9de92a25964e9fa1f0fb9c65a39366
Autor:
Francesco Maione, Paola Minosi, Amalia Di Giannuario, Federica Raucci, Maria Giovanna Chini, Simona De Vita, Giuseppe Bifulco, Nicola Mascolo, Stefano Pieretti
Publikováno v:
Molecules, Vol 24, Iss 13, p 2453 (2019)
The object of the study was to estimate the long-lasting effects induced by ammonium glycyrrhizinate (AG) after a single administration in mice using animal models of pain and inflammation together with biochemical and docking studies. A single intra
Externí odkaz:
https://doaj.org/article/496d937638fc462b968047cf0ddd8503
Autor:
Francesca Marzoli, Carlotta Marianecci, Federica Rinaldi, Daniele Passeri, Marco Rossi, Paola Minosi, Maria Carafa, Stefano Pieretti
Publikováno v:
Pharmaceutics, Vol 11, Iss 2, p 62 (2019)
Ibuprofen is one of the non-steroidal anti-inflammatory drugs (NSAIDs) widely used to treat pain conditions. NSAIDs encounter several obstacles to passing across biological membranes. To overcome these constraints, we decided to study the effects of
Externí odkaz:
https://doaj.org/article/893fdc64426e4565ba9bb533b695c799
Autor:
Azzurra Stefanucci, Paola Minosi, Stefano Pieretti, Parthasaradhireddy Tanguturi, Gabriella Molnar, Giuseppe Scioli, Lorenza Marinaccio, Alice Della Valle, John M. Streicher, Adriano Mollica
Publikováno v:
ACS Chemical Neuroscience. 14:506-515