Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Paola Massarelli"'
Autor:
Maria Rosaria Ambrosio, Elisa Magli, Giuseppe Caliendo, Rosa Sparaco, Paola Massarelli, Vittoria D’Esposito, Teresa Migliaccio, Giusy Mosca, Ferdinando Fiorino, Pietro Formisano
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Serotonin (or 5-Hydroxytryptamine, 5-HT) signals in mammary gland becomes dysregulated in cancer, also contributing to proliferation, metastasis, and angiogenesis. Thus, the discovery of novel compounds targeting serotonin signali
Externí odkaz:
https://doaj.org/article/1ff550da64d74d238fdea77957c3ed5d
Autor:
Giuseppe Caliendo, Giusy Mosca, Rosa Sparaco, Paola Massarelli, Teresa Migliaccio, Maria Rosaria Ambrosio, F. Fiorino, Vittoria D'Esposito, Elisa Magli, Pietro Formisano
Publikováno v:
BMC cancer. 22(1)
Background Serotonin (or 5-Hydroxytryptamine, 5-HT) signals in mammary gland becomes dysregulated in cancer, also contributing to proliferation, metastasis, and angiogenesis. Thus, the discovery of novel compounds targeting serotonin signaling may co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7419bdcc4c1c5266ad1fe39731f262c
https://pubmed.ncbi.nlm.nih.gov/35168555
https://pubmed.ncbi.nlm.nih.gov/35168555
Autor:
Ewa Kędzierska, Elisa Perissutti, Beatrice Severino, Paola Massarelli, Ewa Gibula-Tarlowska, Angela Corvino, Ferdinando Fiorino, Giuseppe Caliendo, Francesco Frecentese, Irene Saccone, Elisa Magli, Agnieszka A. Kaczor, Jolanta Kotlinska, Vincenzo Santagada
N'-Cyanoisonicotinamidine and N'-cyanopicolinamidine derivatives, linked to an arylpiperazine moiety, were prepared and their affinities to the 5-HT1A , 5-HT2A , and 5-HT2C receptors were evaluated. Several of the newly synthesized compounds, tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7640e01e2c1f9e00289a665f213d9cf
http://hdl.handle.net/11365/1079301
http://hdl.handle.net/11365/1079301
Autor:
Jolanta Orzelska-Górka, Elisa Magli, Ferdinando Fiorino, Elisa Perissutti, Paola Massarelli, Cristina Nencini, Vincenzo Santagada, Ewa Kędzierska, Giuseppe Caliendo, Angelo A. Izzo, Ilaria Rossi, Anna Bielenica, Paola Di Vaio, Francesco Frecentese, Angela Corvino, Antonio Ciano, Raffaele Capasso, Beatrice Severino
Publikováno v:
European Journal of Medicinal Chemistry. 110:133-150
Isonicotinamide derivatives, linked to an arylpiperazine moiety, were prepared and their affinity to 5-HT 1A , 5-HT 2A and 5-HT 2C receptors were evaluated. The combination of structural elements (heterocyclic nucleus, alkyl chain and 4-substituted p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200ba6aa23593d7e4b5422322bbbcb86
https://doi.org/10.1016/j.ejmech.2016.01.021
https://doi.org/10.1016/j.ejmech.2016.01.021
Autor:
Elisa, Magli, Ewa, Kędzierska, Agnieszka A, Kaczor, Beatrice, Severino, Angela, Corvino, Elisa, Perissutti, Francesco, Frecentese, Irene, Saccone, Paola, Massarelli, Ewa, Gibuła-Tarłowska, Jolanta H, Kotlińska, Vincenzo, Santagada, Giuseppe, Caliendo, Ferdinando, Fiorino
Publikováno v:
Archiv der Pharmazie. 352(5)
N'-Cyanoisonicotinamidine and N'-cyanopicolinamidine derivatives, linked to an arylpiperazine moiety, were prepared and their affinities to the 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11dcd00b743ccf7d46c80d7302274953
https://pubmed.ncbi.nlm.nih.gov/31025433
https://pubmed.ncbi.nlm.nih.gov/31025433
Autor:
Ferdinando, Fiorino, Elisa, Magli, Ewa, Kędzierska, Antonio, Ciano, Angela, Corvino, Beatrice, Severino, Elisa, Perissutti, Francesco, Frecentese, Paola, Di Vaio, Irene, Saccone, Angelo A, Izzo, Raffaele, Capasso, Paola, Massarelli, Ilaria, Rossi, Jolanta, Orzelska-Gòrka, Jolanta Helena, Kotlińska, Vincenzo, Santagada, Giuseppe, Caliendo
Publikováno v:
Bioorganicmedicinal chemistry. 25(20)
Picolinamide derivatives, linked to an arylpiperazine moiety, were prepared and their affinity to 5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f231184d3493aaefa8d64be839b2fe5d
https://pubmed.ncbi.nlm.nih.gov/28943244
https://pubmed.ncbi.nlm.nih.gov/28943244
Autor:
Francesco Frecentese, Jolanta Orzelska-Górka, Elisa Perissutti, Elisa Magli, Raffaele Capasso, Beatrice Severino, Ewa Kędzierska, Giuseppe Caliendo, Ilaria Rossi, Jolanta Kotlinska, Ferdinando Fiorino, Angela Corvino, Paola Di Vaio, Antonio Ciano, Vincenzo Santagada, Angelo A. Izzo, Irene Saccone, Paola Massarelli
Picolinamide derivatives, linked to an arylpiperazine moiety, were prepared and their affinity to 5-HT1A, 5-HT2A and 5-HT2C receptors was evaluated. The combination of structural elements (heterocyclic nucleus, alkyl chain and 4-substituted piperazin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91d16a6e21a4b5f3a068e1022d747a5
http://hdl.handle.net/11365/1051259
http://hdl.handle.net/11365/1051259
Autor:
Elisa Magli, Angela Corvino, Ferdinando Fiorino, Paola Massarelli, Beatrice Severino, Antonio Ciano, Giuseppe Caliendo, Vincenzo Santagada, Cristina Nencini, Francesco Frecentese, Elisa Perissutti
Publikováno v:
Archiv der Pharmazie. 347:698-706
This paper reports the synthesis of new norbornene and exo-N-hydroxy-7-oxabicyclo[2.2.1]hept-5-ene-2,3-dicarboximide derivatives and their binding to the 5-HT1A , 5-HT2A , and 5-HT2C receptors, in order to identify selective ligands for these 5-hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::474585142ce6acf03d98735f3ad0fe9b
https://doi.org/10.1002/ardp.201400174
https://doi.org/10.1002/ardp.201400174
Autor:
Aleksandra Sawczenko, Michal Kolinski, Sebastian Kmiecik, Anna Bielenica, Anna E. Koziol, Marta Struga, Ferdinando Fiorino, Elisa Magli, Angela Corvino, Ewa Kędzierska, Andrzej Kolinski, Ilaria Rossi, Beatrice Severino, Paola Massarelli
A series of 10 thiourea derivatives have been synthesized by the reaction of aromatic amine with a substituted aryl (compounds 1–3, 6–8) and alkylphenyl (4, 5, 9, 10) isothiocyanates. Their in vitro and in vivo pharmacological properties were stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75891f845f69119febfe09cdc441b1f9
http://hdl.handle.net/11365/1004705
http://hdl.handle.net/11365/1004705
Autor:
Ferdinando Fiorino, Francesca De Angelis, Giuseppe Caliendo, Elisa Perissutti, Antonella Esposito, Cristina Nencini, Paola Massarelli, Beatrice Severino, Francesco Frecentese, Elisa Magli, Vincenzo Santagada
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:2978-2982
N'-cyanoisonicotinamidine derivatives, linked to an arylpiperazine moiety, were prepared to identify highly selective and potent 5-HT(1A) ligands as potential pharmacological tools in studies of wide spread psychiatric disorders. The combination of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de085a10dca9fcd1f26e87df67f5664
https://doi.org/10.1016/j.bmcl.2010.02.106
https://doi.org/10.1016/j.bmcl.2010.02.106