Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Paola Leopardi"'
Autor:
Riccardo Crebelli, Paola Leopardi
Publikováno v:
Annali dell'Istituto Superiore di Sanità, Vol 48, Iss 4, Pp 354-361 (2012)
Metal contaminants in drinking water represent a relevant health issue in several areas of the world. In Italy, because of the geological features of the territory, high arsenic and vanadium are frequently reported in ground waters in concentrations
Externí odkaz:
https://doaj.org/article/ba7f75f306a3451e9eced85ebaa79e12
Autor:
Nieves Palma, Margherita Bignami, Eugenia Dogliotti, Maria Teresa Russo, Pasquale Mosesso, Piero Musiani, Paola Leopardi, Paolo Degan, Gabriele De Luca, Serena Cinelli, Gaetano Pepe, Riccardo Crebelli, Carlo Sorrentino, Emma Di Carlo
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9687, p 9687 (2021)
Volume 22
Issue 18
International Journal of Molecular Sciences, Vol 22, Iss 9687, p 9687 (2021)
Furan is a volatile compound that is formed in foods during thermal processing. It is classified as a possible human carcinogen by international authorities based on sufficient evidence of carcinogenicity from studies in experimental animals. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23cf5ac05d0447b1be65066adaed31c4
Autor:
Elena Dellatte, Patrizia Eleuteri, Ester Siniscalchi, Nicola Iacovella, Riccardo Crebelli, Paola Sestili, Paola Leopardi, Gabriele De Luca, Stefania Caiola, L. Conti, Paola Villani, Eugenia Cordelli, Francesca Marcon, Massimo Sanchez
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 106
PFAS (perfluoroalkyl substances) are considered non-genotoxic. However, PFAS exposure has been associated with the induction of oxidative stress in vitro and in vivo, and the possible induction of indirect genotoxic effects under sustained PFAS expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29767fd405a3d699bcb3874fdddeaeef
https://pubmed.ncbi.nlm.nih.gov/31071380
https://pubmed.ncbi.nlm.nih.gov/31071380
Autor:
Paola Leopardi, Francesca Marcon, Ester Siniscalchi, Riccardo Crebelli, Eugenia Cordelli, Caterina Macrì, L. Conti, Fiorella Malchiodi-Albedi, Paola Villani, Patrizia Eleuteri, Stefania Caiola
Publikováno v:
Mutagenesis. 25:305-314
In this study, the effects induced in mouse liver by repeated oral exposure to furan were investigated. To this aim, the compound was given for 28 days by daily gavage to male B6C3F1 mice at 2, 4, 8 and 15 mg/kg body weight (b.w.)/day. Twenty-four ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad6a5db813ee7dee66da2fc4169f124
https://doi.org/10.1093/mutage/geq007
https://doi.org/10.1093/mutage/geq007
Autor:
Arturo Cafolla, Stefania Caiola, Paola Leopardi, Andrea Zijno, Riccardo Crebelli, Ester Siniscalchi, Francesca Marcon
Publikováno v:
Mutagenesis. 21:327-333
Folic acid plays a key role in the maintenance of genomic stability, providing methyl groups for the conversion of uracil to thymine and for DNA methylation. Besides dietary habits, folic acid metabolism is influenced by genetic polymorphism. The C67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fa9996b90581e5692606d3a008d3db
https://doi.org/10.1093/mutage/gel031
https://doi.org/10.1093/mutage/gel031
Autor:
Francesca Degrassi, Antonella Sgura, A. Antoccia, Caterina Tanzarella, Angelo Carere, Daniela Cimini, Francesca Marcon, Paola Leopardi, Riccardo Crebelli, Andrea Zijno
Publikováno v:
Mutagenesis. 14:491-496
Chromosome malsegregation in peripheral blood lymphocytes of 24 healthy male subjects was analysed by means of fluorescence in situ hybridization with centromeric probes of chromosomes 7, 11, 18 and X. On the basis of the distribution of centromeric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1152328134642ada9ea9b923eaaa83
https://doi.org/10.1093/mutage/14.5.491
https://doi.org/10.1093/mutage/14.5.491
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 372:211-219
The application of methods based on in situ hybridization to centromeric regions to cytokinesis-blocked cells provides a convenient way for the analysis of chromosome segregation in interphase cells. In this way, the reciprocal segregation patterns i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8145b994359bc95360e691daaed307
https://doi.org/10.1016/s0027-5107(96)00141-8
https://doi.org/10.1016/s0027-5107(96)00141-8
Publikováno v:
Chromosoma. 104:461-467
Chromosomal lagging and non-disjunction are the main mechanisms of chromosomal malsegregation at mitosis. To date, the relative importance of these two events in the genesis of spontaneous or induced aneuploidy has not been fully elucidated. A method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00abf85e8d5c841d073e93d5cb64f30e
https://doi.org/10.1007/bf00352270
https://doi.org/10.1007/bf00352270
Publikováno v:
Mutagenesis. 11:335-340
The chromosome malsegregation pattern produced by the spindle poisons vinblastine (VBL) and colchicine (COL) in human lymphocytes was investigated. For this purpose, the fluorescence in situ hybridization with centromeric DNA probes for chromosomes X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b12dd7dc6c5e6eaf71878e888f2986
https://doi.org/10.1093/mutage/11.4.335
https://doi.org/10.1093/mutage/11.4.335
Autor:
Daniela Carotti, Ester Siniscalchi, Riccardo Crebelli, Andrea Zijno, Mauro Biffoni, Paola Leopardi, Cristina Andreoli, Francesca Marcon, Sabrina Rossi, Stefania Caiola, Emanuela Medda, Lorenza Nisticò
Publikováno v:
Mutagenesis. 28(2)
Previous studies in twins indicate that non-shared environment, beyond genetic factors, contributes substantially to individual variation in mutagen sensitivity; however, the role of specific causative factors (e.g. tobacco smoke, diet) was not eluci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df664e239349bb4c6f390c71dbbbe45
https://pubmed.ncbi.nlm.nih.gov/23132286
https://pubmed.ncbi.nlm.nih.gov/23132286