Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Paola Lasso"'
Autor:
Carolina Carlosama, Cindy Arévalo, María Camila Jimenez, Paola Lasso, Claudia Urueña, Susana Fiorentino, Alfonso Barreto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Tumor metabolism is a crucial aspect of cancer development, and mitochondria plays a significant role in the aggressiveness and metastasis of tumors. As a result, mitochondria have become a promising therapeutic target in cancer treatment, l
Externí odkaz:
https://doaj.org/article/8cff2678565a44d9a698f467022f5443
Publikováno v:
Journal of Toxicology, Vol 2024 (2024)
Although herbal drugs are often considered safe for consumption, there is increasing evidence that some can generate undesirable health effects. However, polyphenols found in certain plants have been shown to provide a range of benefits for human hea
Externí odkaz:
https://doaj.org/article/1664e432fbfb420e8ca0faaeb0bfb9e6
Autor:
Karol Prieto, Cindy Arévalo, Paola Lasso, Carolina Carlosama, Claudia Urueña, Susana Fiorentino, Alfonso Barreto
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23403- (2024)
The Covid-19 infection outbreak led to a global epidemic, and although several vaccines have been developed, the appearance of mutations has allowed the virus to evade the immune response. Added to this is the existing risk of the appearance of new e
Externí odkaz:
https://doaj.org/article/1097fbe92f204422a8e8fa36aeeb1328
Autor:
Daniel Pardo-Rodriguez, Paola Lasso, Mary Santamaría-Torres, Mónica P. Cala, Concepción J. Puerta, Jonh Jairo Méndez Arteaga, Jorge Robles, Claudia Cuervo
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Chagas disease (ChD), caused by Trypanosoma cruzi, is endemic in American countries and an estimated 8 million people worldwide are chronically infected. Currently, only two drugs are available for therapeutic use against T. cruzi and their use is co
Externí odkaz:
https://doaj.org/article/732db7ca460c4179bc41c719d2d7afcd
Autor:
Laura Rojas, Daniel Pardo-Rodriguez, Claudia Urueña, Paola Lasso, Cindy Arévalo, Mónica P. Cala, Susana Fiorentino
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17418 (2023)
Previously, studies have shown that leukemic cells exhibit elevated glycolytic metabolism and oxidative phosphorylation in comparison to hematopoietic stem cells. These metabolic processes play a crucial role in the growth and survival of leukemic ce
Externí odkaz:
https://doaj.org/article/b260cca5aae1494db90bc57d3e050e45
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16698 (2023)
Natural products obtained from Petiveria alliacea (Anamu-SC) and Caesalpinia spinosa (P2Et) have been used for cancer treatment, but the mechanisms by which they exert their antitumor activity appear to be different. In the present work, we show that
Externí odkaz:
https://doaj.org/article/67fe334ee4e24ba29b428c907017fdfb
Autor:
Claudia Urueña, Paola Lasso, David Bernal-Estevez, Diego Rubio, Ana Janeth Salazar, Mercedes Olaya, Alfonso Barreto, Mauricio Tawil, Lilian Torregrosa, Susana Fiorentino
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Neoadjuvant chemotherapy (NAT) in breast cancer (BC) has been used to reduce tumor burden prior to surgery. However, the impact on prognosis depends on the establishment of Pathological Complete Response (pCR), which is influenced by tumor-i
Externí odkaz:
https://doaj.org/article/a8f890c9820e430a9a4b5b080c0fdc29
Autor:
Maria Camila Jiménez, Karol Prieto, Paola Lasso, Melisa Gutiérrez, Viviana Rodriguez-Pardo, Susana Fiorentino, Alfonso Barreto
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e14148- (2023)
Interactions in the tumor microenvironment (TME) between tumor cells and stromal cells such as cancer-associated fibroblasts (CAF) favor increased survival, progression, and transformation of cancer cells by activating mechanisms of invasion and meta
Externí odkaz:
https://doaj.org/article/7fecebc19cc34a72932f631dc155a2f2
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
Trypanosoma cruzi, the causal agent of Chagas disease, has coexisted with humans for thousands of years. Therefore, the parasite has developed several mechanisms of antigenic variability that has allowed it to live inside the cells and evade the host
Externí odkaz:
https://doaj.org/article/7e121e2c8ba044c8a6521e414f56a859
Autor:
Natalia Murillo, Paola Lasso, Claudia Urueña, Daniel Pardo-Rodriguez, Ricardo Ballesteros-Ramírez, Giselle Betancourt, Laura Rojas, Mónica P. Cala, Susana Fiorentino
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12972 (2023)
The poor response, adverse effects and drug resistance to treatment of acute myeloid leukemia (AML) have led to searching for safer and more effective therapeutic alternatives. We previously demonstrated that the alcoholic extract of Petiveria alliac
Externí odkaz:
https://doaj.org/article/626dc20ebf1a4a36bebf0033e19cc448