Výsledky vyhledávání - "Paola Guizar"

Akademický článek

An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity

Autor: Paola Guizar, Ana Luiza Abdalla, Anne Monette, Kristin Davis, Ramon Edwin Caballero, Meijuan Niu, Xinyun Liu, Oluwaseun Ajibola, Thomas T. Murooka, Chen Liang, Andrew J. Mouland

Publikováno v: iScience, Vol 27, Iss 6, Pp 110131- (2024)

Summary: HIV-1 hijacks host proteins involved in membrane trafficking, endocytosis, and autophagy that are critical for virus replication. Molecular details are lacking but are essential to inform on the development of alternative antiviral strategie

Externí odkaz: https://doaj.org/article/00c18013ef8e4b1b99da5bbe44a51b53

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The double-stranded RNA-binding protein, Staufen1, is an IRES-transacting factor regulating HIV-1 cap-independent translation initiation

Autor: Hade Ramos, Anne Monette, Meijuan Niu, Aldo Barrera, Brenda López-Ulloa, Yazmín Fuentes, Paola Guizar, Karla Pino, Luc DesGroseillers, Andrew J Mouland, Marcelo López-Lastra

Publikováno v: Nucleic Acids Research

Translation initiation of the viral genomic mRNA (vRNA) of human immunodeficiency virus-type 1 (HIV-1) can be mediated by a cap- or an internal ribosome entry site (IRES)-dependent mechanism. A previous report shows that Staufen1, a cellular double-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528f84dacd0723bf1dd816747aa182ab
http://europepmc.org/articles/PMC8754648

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