Výsledky vyhledávání - "Paola Galbani"

Sulfhydryl Redox State Affects Susceptibility to Ischemia and Sarcoplasmic Reticulum Ca 2+ Release in Rat Heart

Autor: Gongyuan Yu, Giovanni Ronca, Riccardo Zucchi, Mario Mariani, Paola Galbani, Simonetta Ronca-Testoni

Publikováno v: Circulation Research. 83:908-915

Abstract —We investigated the effect of sulfhydryl and disulfide reagents on ischemic preconditioning and on sarcoplasmic reticulum Ca 2+ release. Isolated working rat hearts were subjected to ischemic preconditioning (three 3-minute periods of glo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af4a4d19880075ad4c30cdbbae8ff4e
https://doi.org/10.1161/01.res.83.9.908

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Effect of Gallopamil on Cardiac Sarcoplasmic Reticulum

Autor: Giovanni Ronca, Riccardo Zucchi, Gongyuan Yu, Simonetta Ronca-Testoni, Paola Galbani, Mario Mariani, Ugo Limbruno

Publikováno v: Scopus-Elsevier
Europe PubMed Central

We investigated the effect of gallopamil on cardiac sarcoplasmic reticulum (SR) function. Heavy SR was prepared from bovine ventricular muscle. Oxalate-supported calcium uptake was stimulated by gallopamil at concentrations ranging from 10 to 300 nM,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1550f83f247ab5e10451619523cda948
https://doi.org/10.1097/00005344-199200207-00003

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Postischemic changes in cardiac sarcoplasmic reticulum Ca2+ channels. A possible mechanism of ischemic preconditioning

Autor: Paola Galbani, Simonetta Ronca-Testoni, Giovanni Ronca, Mario Mariani, Riccardo Zucchi, Gongyuan Yu

Publikováno v: Circulation research. 76(6)

Abstract We investigated the modifications of cardiac ryanodine receptors/sarcoplasmic reticulum Ca 2+ release channels occurring in ischemic preconditioning. In an isolated rat heart model, the injury produced by 30 minutes of global ischemia was re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3869f7a00a8882f25a35fd1e2e12fa
https://pubmed.ncbi.nlm.nih.gov/7758159

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Interaction between gallopamil and cardiac ryanodine receptors

Autor: Simonetta Ronca-Testoni, Paola Galbani, Mario Mariani, Riccardo Zucchi, Gongyuan Yu, Giovanni Ronca

Publikováno v: Scopus-Elsevier

1. In a sarcoplasmic reticulum fraction obtained from rat hearts, the analysis of equilibrium [3H]-ryanodine binding showed high and low affinity sites (KD = 1.3 nM and 2.8 microM, Bmax = 2.2 pmol mg-1 and 27.8 pmol mg-1). The dissociation rate const

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a8b19aff3ec1ef4e093d630f645a66
https://pubmed.ncbi.nlm.nih.gov/7712034

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Are dihydropyridine receptors downregulated in the ischemic myocardium?

Autor: Paola Galbani, Giovanni Ronca, Simonetta Ronca-Testoni, Gongyuan Yu, Riccardo Zucchi, Mario Mariani

Objective: We investigated the effect of ischemia on cardiac dihydropyridine receptors, which correspond to L-type sarcolemmal calcium channels. Methods: Isolated working rat hearts were perfused aerobically for 10 min, and then subjected to 10–60

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43a404eed19747f4b3b395856ded8d2
http://hdl.handle.net/11568/174566

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Effect of ischemia and reperfusion on cardiac ryanodine receptors--sarcoplasmic reticulum Ca2+ channels

Autor: Gongyuan Yu, Simonetta Ronca-Testoni, Riccardo Zucchi, Mario Mariani, Giovanni Ronca, Paola Galbani

Publikováno v: Circulation research. 74(2)

We investigated the effect of ischemia and reperfusion on the cardiac ryanodine receptor, which corresponds to the sarcoplasmic reticulum Ca2+ channel. Isolated working rat hearts were subjected to 10 to 30 minutes of global ischemia, followed or not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b4baeef63e84720f1ecfd26d51f248
https://pubmed.ncbi.nlm.nih.gov/8293566

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Effect of Ischaemia on Cardiac Adenosine Binding Sites

Autor: Simonetta Ronca-Testoni, Ugo Limbruno, Giovanni Ronca, Riccardo Zucchi, Mario Mariani, Paola Galbani

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781489926401

Adenosine produces different effects on the heart. It markedly increases coronary blood flow and exerts negative inotropic, chronotropic and dromotropic effects on atrial myocardium. Adenosine does not appear to have any direct action on ventricular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641838b7b7ec4ca1b8519d9cc3b35e5e
https://doi.org/10.1007/978-1-4899-2638-8_103

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