Zobrazeno 1 - 10
of 180
pro vyhledávání: '"Paola Fossa"'
Autor:
Giancarlo Grossi, Naomi Scarano, Francesca Musumeci, Michele Tonelli, Evgeny Kanov, Anna Carbone, Paola Fossa, Raul R. Gainetdinov, Elena Cichero, Silvia Schenone
Publikováno v:
Molecules, Vol 29, Iss 8, p 1739 (2024)
The search for novel effective TAAR1 ligands continues to draw great attention due to the wide range of pharmacological applications related to TAAR1 targeting. Herein, molecular docking studies of known TAAR1 ligands, characterized by an oxazoline c
Externí odkaz:
https://doaj.org/article/c00b5f6dfd8e4b0f9d0943f5ad4f6b79
Autor:
Paola Fossa
Publikováno v:
Między Oryginałem a Przekładem, Vol 29, Iss 3(61) (2023)
(UN)TRANSLATABLE: RECENT FRENCH TRANSLATION STUDIES ON FROZEN EXPRESSIONS AND PUNS Frozen expressions and puns can be compared in terms of translation solutions. As plural elements and because of their idiomaticity and cultural charge, they have l
Externí odkaz:
https://doaj.org/article/94a935b01afd43c6bb48546d903d9155
Autor:
Debora Baroni, Naomi Scarano, Alessandra Ludovico, Chiara Brandas, Alice Parodi, Dario Lunaccio, Paola Fossa, Oscar Moran, Elena Cichero, Enrico Millo
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1702 (2023)
Cystic fibrosis (CF), the most common autosomal recessive fatal genetic disease in the Caucasian population, is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR), an anion channel that regulates s
Externí odkaz:
https://doaj.org/article/e98237455bcb4b93b338fd4789aa0e3d
Autor:
Pasqualina D’Ursi, Paola Fossa
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 792 (2022)
The Biomolecules Special issue on “An Update on CFTR Drug Discovery: Opportunities and Challenges” includes three original research articles and a webinar session focusing on some recent findings concerning CFTR drug discovery [...]
Externí odkaz:
https://doaj.org/article/90280671b89d4610a0fbdb53e3020fd8
Autor:
Valeria Iobbi, Anna Paola Lanteri, Andrea Minuto, Valentina Santoro, Giuseppe Ferrea, Paola Fossa, Angela Bisio
Publikováno v:
Molecules, Vol 27, Iss 3, p 760 (2022)
Tomato brown rugose fruit virus (ToBRFV) is a new damaging plant virus of great interest from both an economical and research point of view. ToBRFV is transmitted by contact, remains infective for months, and to-date, no resistant cultivars have been
Externí odkaz:
https://doaj.org/article/adaa7cbb8c2b466c88c38ca4391a593e
Autor:
Elena Cichero, Alessio Calautti, Valeria Francesconi, Michele Tonelli, Silvia Schenone, Paola Fossa
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1307 (2021)
Targeting the fusion (F) protein has been recognized as a fruitful strategy for the development of anti-RSV agents. Despite the considerable efforts so far put into the development of RSV F protein inhibitors, the discovery of adequate therapeutics f
Externí odkaz:
https://doaj.org/article/453075f856014baf84057f62874d942d
Autor:
Valeria Iobbi, Paola Brun, Giulia Bernabé, Roméo Arago Dougué Kentsop, Giuliana Donadio, Barbara Ruffoni, Paola Fossa, Angela Bisio, Nunziatina De Tommasi
Publikováno v:
Molecules, Vol 26, Iss 21, p 6681 (2021)
Quorum-sensing (QS) is a regulatory mechanism in bacterial communication, important for pathogenesis control. The search for small molecules active as quorum-sensing inhibitors (QSI) that can synergize with antibiotics is considered a good strategy t
Externí odkaz:
https://doaj.org/article/9a27fe9ae5644f3a8fce8919ad19f9d9
Autor:
Alessandro Rondina, Paola Fossa, Alessandro Orro, Luciano Milanesi, Antonella De Palma, Davide Perico, Pier Luigi Mauri, Pasqualina D’Ursi
Publikováno v:
Cells, Vol 10, Iss 11, p 3225 (2021)
Boron Neutron Capture Therapy (BNCT) is a tumor cell-selective radiotherapy based on a nuclear reaction that occurs when the isotope boron-10 (10B) is radiated by low-energy thermal neutrons or epithermal neutrons, triggering a nuclear fission respon
Externí odkaz:
https://doaj.org/article/17f18813770e4ea0bfacae64a0c26105
Autor:
Sara Guariento, Silvia Franchini, Michele Tonelli, Paola Fossa, Claudia Sorbi, Elena Cichero, Livio Brasili
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 214-230 (2017)
The 5-hydroxytryptamine (5-HT1A) receptors represent an attractive target in drug discovery. In particular, 5-HT1A agonists and partial agonists are deeply investigated for their potential role in the treatment of anxiety, depression, ischaemic brain
Externí odkaz:
https://doaj.org/article/6b7bb9906c81442d9059067a45053d12
Autor:
Vito Boido, Marcella Ercoli, Michele Tonelli, Federica Novelli, Bruno Tasso, Fabio Sparatore, Elena Cichero, Paola Fossa, Paola Dorigo, Guglielmina Froldi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 588-599 (2017)
Positive inotropic agents are fundamental in the treatment of heart failure; however, their arrhythmogenic liability and the increased myocardial oxygen demand strongly limit their therapeutic utility. Pursuing our study on cardiovascular activities
Externí odkaz:
https://doaj.org/article/8a8b34dde1414dbf8e141cd391ec21a0