Výsledky vyhledávání - "Paola Fontannaz"

Akademický článek

Influence of circadian clocks on adaptive immunity and vaccination responses

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)

Circadian rhythms have been shown to influence immune responses, but it is unclear whether this influences responses to vaccines. Here the authors show that dendritic cells migrate in a circadian rhythm meaning that interactions with T cells are alte

Externí odkaz: https://doaj.org/article/4a62447920cd4f83a5fd19b48d8d06ab

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Akademický článek

Antibody response in children with multisystem inflammatory syndrome related to COVID-19 (MIS-C) compared to children with uncomplicated COVID-19

Autor: Anaïs Thiriard, Benjamin Meyer, Christiane S. Eberhardt, Natasha Loevy, Serge Grazioli, Wafae Adouan, Paola Fontannaz, Fabienne Marechal, Arnaud G. L’Huillier, Claire-Anne Siegrist, Daphnée Georges, Antonella Putignano, Arnaud Marchant, Arnaud M. Didierlaurent, Geraldine Blanchard-Rohner

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

ObjectivesTo comprehensively analyze the quality of the antibody response between children with Multisystem inflammatory syndrome (MIS-C) and age-matched controls at one month after SARS-CoV-2 exposure, and infected in the same time-period.MethodsSer

Externí odkaz: https://doaj.org/article/d415f9a6f39b4a8abbf3231fc0c29db0

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Akademický článek

Fitness of B-Cell Responses to SARS-CoV-2 WT and Variants Up to One Year After Mild COVID-19 – A Comprehensive Analysis

Autor: Benjamin Meyer, Paola Andrea Martinez-Murillo, Barbara Lemaitre, Géraldine Blanchard-Rohner, Arnaud M. Didierlaurent, Paola Fontannaz, Chloé Eugercios Manzanas, Paul-Henri Lambert, Natasha Loevy, Laurent Kaiser, Julie Sartoretti, Chantal Tougne, Jean Villard, Angela Huttner, Claire-Anne Siegrist, Christiane S. Eberhardt

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

ObjectiveTo comprehensively evaluate SARS-CoV-2 specific B-cell and antibody responses up to one year after mild COVID-19.MethodsIn 31 mildly symptomatic COVID-19 participants SARS-CoV-2-specific plasmablasts and antigen-specific memory B cells were

Externí odkaz: https://doaj.org/article/50af9623e03f4b5980906bce4cd6caaa

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Akademický článek

Reactivating Immunity Primed by Acellular Pertussis Vaccines in the Absence of Circulating Antibodies: Enhanced Bacterial Control by TLR9 Rather Than TLR4 Agonist-Including Formulation

Autor: Floriane Auderset, Marie Ballester, Beatris Mastelic-Gavillet, Paola Fontannaz, Martine Chabaud-Riou, Nathalie Reveneau, Marie Garinot, Noëlle Mistretta, Yuanqing Liu, Paul-Henri Lambert, Martina Ochs, Claire-Anne Siegrist

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Pertussis is still observed in many countries despite of high vaccine coverage. Acellular pertussis (aP) vaccination is widely implemented in many countries as primary series in infants and as boosters in school-entry/adolescents/adults (including pr

Externí odkaz: https://doaj.org/article/cd03835ead6f409fb839b93787ad1851

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Akademický článek

Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life.

Autor: Elodie Belnoue, Paola Fontannaz, Anne-Françoise Rochat, Chantal Tougne, Andreas Bergthaler, Paul-Henri Lambert, Daniel D Pinschewer, Claire-Anne Siegrist

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e85302 (2013)

Infant mortality from viral infection remains a major global health concern: viruses causing acute infections in immunologically mature hosts often follow a more severe course in early life, with prolonged or persistent viral replication. Similarly,

Externí odkaz: https://doaj.org/article/7e2c1e8b65d647c3abe52c2d8c51b1c4

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Influence of Timing of Maternal Pertussis Immunization on the Avidity of Transferred Antibodies in Term and Preterm Neonates

Autor: Julie Sartoretti, Paola Fontannaz, Begoña Martinez de Tejada, Véronique Othenin-Girard, Antonina Chilin, Barbara Lemaître, Géraldine Blanchard-Rohner, Claire-Anne Siegrist, Christiane Sigrid Eberhardt

Publikováno v: Clinical Infectious Diseases.

The timing of maternal pertussis vaccination influences the titers of cord-blood anti-pertussis antibodies. Whether it affects their avidity is unknown. We demonstrate in 298 term and 72 preterm neonates that antibody avidity is independent of the ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a492f9fb2c1cb0d775beb982233f987e
https://doi.org/10.1093/cid/ciad227

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Omicron-Specific Cytotoxic T-Cell Responses After a Third Dose of mRNA COVID-19 Vaccine Among Patients With Multiple Sclerosis Treated With Ocrelizumab

Autor: Natacha Madelon, Nelli Heikkilä, Irène Sabater Royo, Paola Fontannaz, Gautier Breville, Kim Lauper, Rachel Goldstein, Alba Grifoni, Alessandro Sette, Claire-Anne Siegrist, Axel Finckh, Patrice H. Lalive, Arnaud M. Didierlaurent, Christiane S. Eberhardt

Publikováno v: JAMA Neurol

IMPORTANCE: The SARS-CoV-2 variant B.1.1.529 (Omicron) escapes neutralizing antibodies elicited after COVID-19 vaccination, while T-cell responses might be better conserved. It is crucial to assess how a third vaccination modifies these responses, pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9599fea09cb2cac5dfc0412b57a59ae
https://pubmed.ncbi.nlm.nih.gov/35212717

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Reactivating Immunity Primed by Acellular Pertussis Vaccines in the Absence of Circulating Antibodies: Enhanced Bacterial Control by TLR9 Rather Than TLR4 Agonist-Including Formulation

Autor: Martine Chabaud-Riou, Marie Ballester, Paul-Henri Lambert, Floriane Auderset, Paola Fontannaz, Yuanqing Liu, Nathalie Reveneau, Marie Garinot, Beatris Mastelic-Gavillet, Noëlle Mistretta, Claire-Anne Siegrist, Martina Ochs

Publikováno v: Frontiers in Immunology, Vol. 10 (2019) P. 1520
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32443589af22e24c53b763db61e6139
https://archive-ouverte.unige.ch/unige:143480

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Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes

Autor: Isabelle Dunand-Sauthier, Walter Reith, Marie-Laure Santiago-Raber, Carla Lippens, Vishal Agrawal, Beatris Mastelic-Gavillet, Kerstin Sarter, Claire-Anne Siegrist, Fernanda V. Duraes, Florian Gobet, Giovanni Magistrelli, Ulla Ravn, Elisa Leimgruber, Stéphanie Hugues, Nicolas Fischer, Arun T. Kamath, Paola Fontannaz, Emmanuèle Barras, Leslie Guéry

Publikováno v: J Exp Med
The Journal of Experimental Medicine
The Journal of experimental medicine
Journal of Experimental Medicine, Vol. 213, No 2 (2016) pp. 177-187

Butyrophilins are proteins secreted during lactation and thought to influence immune function. Sarter et al. generated butyrophilin-2a2–deficient mice to show enhanced effector T cell responses, antitumor responses, and exacerbated EAE due to the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2a8ebd0cd6f9beb1ba6325bb8ac172
https://doi.org/10.1084/jem.20150435

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Environmental and T Cell–Intrinsic Factors Limit the Expansion of Neonatal Follicular T Helper Cells but May Be Circumvented by Specific Adjuvants

Autor: Anne-Françoise Rochat, Paul-Henri Lambert, Fabienne Tacchini-Cottier, Floriane Auderset, Elodie Belnoue, Arun T. Kamath, Béatris Mastelic, Christophe Combescure, Paola Fontannaz, Chantal Tougne, Claire-Anne Siegrist

Publikováno v: J Immunol
Journal of immunology (Baltimore Md. : 1950)
Journal of Immunology, Vol. 189, No 12 (2012) pp. 5764-72

Follicular Th (TFH) cells have emerged as a new Th subset providing help to B cells and supporting their differentiation into long-lived plasma cells or memory B cells. Their differentiation had not yet been investigated following neonatal immunizati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a928fe9cebcbb61e4fbd3cc8b17aeb
http://www.jimmunol.org/content/189/12/5764.long

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