Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Paola Failli"'
Autor:
Laura Micheli, Carmen Parisio, Elena Lucarini, Alessia Vona, Alessandra Toti, Alessandra Pacini, Tommaso Mello, Serena Boccella, Flavia Ricciardi, Sabatino Maione, Grazia Graziani, Pedro Miguel Lacal, Paola Failli, Carla Ghelardini, Lorenzo Di Cesare Mannelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/d12524d8a88b4fb8a2a5f9618be81508
Autor:
Laura Micheli, Carmen Parisio, Elena Lucarini, Alessia Vona, Alessandra Toti, Alessandra Pacini, Tommaso Mello, Serena Boccella, Flavia Ricciardi, Sabatino Maione, Grazia Graziani, Pedro Miguel Lacal, Paola Failli, Carla Ghelardini, Lorenzo Di Cesare Mannelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Abstract Background Neuropathic pain is a clinically relevant adverse effect of several anticancer drugs that markedly impairs patients’ quality of life and frequently leads to dose reduction or therapy discontinuation. The poor knowledge about the
Externí odkaz:
https://doaj.org/article/bb197a08c90448299e855843eb5aad6d
Autor:
Alessandra Toti, Laura Micheli, Elena Lucarini, Valentina Ferrara, Clara Ciampi, Francesco Margiotta, Paola Failli, Chiara Gomiero, Marco Pallecchi, Gianluca Bartolucci, Carla Ghelardini, Lorenzo Di Cesare Mannelli
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 233 (2023)
Persistent pain can be managed with opioids, but their use is limited by the onset of tolerance. Ultramicronized N-palmitoylethanolamine (PEA) in vivo delays morphine tolerance with mechanisms that are still unclear. Since glial cells are involved in
Externí odkaz:
https://doaj.org/article/694d7a9e5e674d389ae3aee87bac628a
Autor:
Mariaconcetta Durante, Silvia Sgambellone, Laura Lucarini, Paola Failli, Annunziatina Laurino, Debora Collotta, Gustavo Provensi, Emanuela Masini, Massimo Collino
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
It is known that fructose may contribute to myocardial vulnerability to ischemia/reperfusion (I/R) injury. D-tagatose is a fructose isomer with less caloric value and used as low-calorie sweetener. Here we compared the metabolic impact of fructose or
Externí odkaz:
https://doaj.org/article/041abf166ee64307b195e06e1b83498e
Autor:
Natalia Di Pietro, Maria Assunta Potenza, Sara Di Silvestre, Francesco Addabbo, Nadia Di Pietrantonio, Pamela Di Tomo, Caterina Pipino, Domitilla Mandatori, Carola Palmerini, Paola Failli, Mario Bonomini, Monica Montagnani, Assunta Pandolfi
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202354 (2018)
The potential role of calcimimetics as vasculotropic agents has been suggested since the discovery that calcium sensing receptors (CaSRs) are expressed in cardiovascular tissues. However, whether this effect is CaSR-dependent or -independent is still
Externí odkaz:
https://doaj.org/article/c83f53728d0f4a2092d20abd115d88c3
Autor:
Silvia Nistri, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Matteo Zanardelli, Daniele Bani, Paola Failli
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 9524-9535 (2015)
We demonstrated that in coronary endothelial cells (RCEs) from normotensive Wistar Kyoto rats (WKY), the hormone relaxin (RLX) increases NO production and reduces calcium transients by a NO-related mechanism. Since an impairment of the NO pathway has
Externí odkaz:
https://doaj.org/article/8a83e435af364fe88b643754d0650533
Autor:
Valentina Spinelli, Alessia Vona, Francesca Corti, Lorenzo Diolaiuti, Matteo Zanardelli, Laura Sartiani, Paola Failli
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Introduction and Aim. Nitric oxide (NO) can trigger cardiac differentiation of embryonic stem cells (ESCs), indicating a cardiogenic function of the NO synthetizing enzyme(s) (NOS). However, the involvement of the NO/NOS downstream effectors soluble
Externí odkaz:
https://doaj.org/article/0848de7c15634512881a8b29b6316aef
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
Neuropathies are characterized by a complex response of the central nervous system to injuries. Glial cells are recruited to maintain neuronal homeostasis but dysregulated activation leads to pain signaling amplification and reduces the glial neuropr
Externí odkaz:
https://doaj.org/article/0787dc65ea1448aab812c71116b77adf
Autor:
Matteo Zanardelli, Laura Micheli, Lorenzo Cinci, Paola Failli, Carla Ghelardini, Lorenzo Di Cesare Mannelli
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102758 (2014)
The development of neuropathic syndromes is an important, dose limiting side effect of anticancer agents like platinum derivates, taxanes and vinca alkaloids. The causes of neurotoxicity are still unclear but the impairment of the oxidative equilibri
Externí odkaz:
https://doaj.org/article/a83c444a7525400caac9e576ea1d6ed9
Autor:
Cristina Grossi, Stefania Rigacci, Stefano Ambrosini, Teresa Ed Dami, Ilaria Luccarini, Chiara Traini, Paola Failli, Andrea Berti, Fiorella Casamenti, Massimo Stefani
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71702 (2013)
The claimed beneficial effects of the Mediterranean diet include prevention of several age-related dysfunctions including neurodegenerative diseases and Alzheimer-like pathology. These effects have been related to the protection against cognitive dec
Externí odkaz:
https://doaj.org/article/ee980c16a30c4ec89cf36b9cbb5a6035