Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Paola Dorigo"'
Autor:
Vito Boido, Marcella Ercoli, Michele Tonelli, Federica Novelli, Bruno Tasso, Fabio Sparatore, Elena Cichero, Paola Fossa, Paola Dorigo, Guglielmina Froldi
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 588-599 (2017)
Positive inotropic agents are fundamental in the treatment of heart failure; however, their arrhythmogenic liability and the increased myocardial oxygen demand strongly limit their therapeutic utility. Pursuing our study on cardiovascular activities
Externí odkaz:
https://doaj.org/article/8a8b34dde1414dbf8e141cd391ec21a0
Autor:
Maura Floreani, Guglielmina Froldi, Maurizio Cavalli, Sergio Bova, Maria Cecilia Giron, Katia Varani, Stefania Gessi, Pier Andrea Borea, Maria Teresa Dorigo, Paola Dorigo
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 1, Pp 115-123 (2004)
We evaluated in vitro, in myocardial and vascular preparations isolated from reserpine-treated rats, the intrinsic sympathomimetic activity (ISA) of carteolol, a β1/β2-adrenoceptor blocking agent used in cardiovascular and non-cardiovascular diseas
Externí odkaz:
https://doaj.org/article/86690e3457954e929bed479312e329ee
Autor:
Paola Dorigo, Guglielmina Froldi
Publikováno v:
Medical Hypotheses
Several risk factors are associated with a worse outcome for COVID-19 patients; the most recognized are demographic characteristics such as older age and male gender, and pre-existing cardiovascular conditions. About the latter, hypertension and coro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb04ec7468e43823664d3afafb9d73f
Autor:
Paola Dorigo, Michele Tonelli, Vito Boido, Marcella Ercoli, Fabio Sparatore, Bruno Tasso, Guglielmina Froldi, Paola Fossa, Federica Novelli, Elena Cichero
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 588-599 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 588-599 (2017)
Positive inotropic agents are fundamental in the treatment of heart failure; however, their arrhythmogenic liability and the increased myocardial oxygen demand strongly limit their therapeutic utility. Pursuing our study on cardiovascular activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd801ee69a59b9048aec34b6dffd3963
http://europepmc.org/articles/PMC6009970
http://europepmc.org/articles/PMC6009970
Autor:
Paola Dorigo, F Lonardoni, Eugenio Ragazzi, Laura Caparrotta, Stefano Mammi, Guglielmina Froldi, Monica Montopoli, Massimo Bellanda
Publikováno v:
Current Cancer Drug Targets. 11:226-235
The way cancer cells escape cisplatin-induced apoptosis has not been completely elucidated yet. We questioned the relevance of "metabolic reprogramming" in cisplatin-resistance by studying mitochondrial function and metabolism in human ovarian carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13b55762e7feabeae42d32cc7ba8ee27
https://doi.org/10.2174/156800911794328501
https://doi.org/10.2174/156800911794328501
Publikováno v:
Pharmacology. 81:70-78
The effects of 5-hydroxytryptamine (5-HT), 5-carboxamidotryptamine, and sumatriptan on rat caudal arteries were examined, with the goal of finding experimental conditions useful in enhancing the ‘silent’ 5-HT1B receptor subtype. It was shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebd233140ba6e75720bbd4e31f19f170
https://doi.org/10.1159/000109297
https://doi.org/10.1159/000109297
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 367:109-118
Two mechanisms are responsible for the positive inotropic effect of the cardiotonic drug milrinone, i.e., inhibition of type III cAMP phosphodiesterase (PDE III), and displacement of endogenous adenosine from A(1) inhibitory receptor. Since PDE III i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523045386ff0528fc5fd0aa9904fc1fd
https://doi.org/10.1007/s00210-002-0675-2
https://doi.org/10.1007/s00210-002-0675-2
Publikováno v:
British Journal of Pharmacology. 127:505-513
1. To investigate the role of endothelium in vascular spasm, we studied the influence of endothelin-1 (ET-1) on the contracting and spasmogenic effect of the K+-channel blocker, tetraethylammonium (TEA), in aorta rings of reserpine-treated guinea-pig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac29b3476c73a802f8020b213a56b86b
https://doi.org/10.1038/sj.bjp.0702557
https://doi.org/10.1038/sj.bjp.0702557
Publikováno v:
British Journal of Pharmacology. 121:972-976
Purine compounds such as ATP and adenosine, respectively endothelium-dependent and-independent vasodilators, are largely involved in the control of vascular tone and vascular reactivity to contracting stimuli. We investigated the relaxing activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a88b14bd1beaa79b314aeb2df8be479
https://doi.org/10.1038/sj.bjp.0701203
https://doi.org/10.1038/sj.bjp.0701203
Autor:
Maura Floreani, Paola Dorigo, Rosa Maria Gaion, P. A. Borea, Santostasi G, Luisa Mosti, I. Maragno, D. Fraccarollo
Publikováno v:
General Pharmacology: The Vascular System. 28:781-788
1. 1. Two new milrinone analogs, 3-acetyl-6-phenyl-2(IH)-pyridone (SF 348) and 3-acetyl-7-methyl-7,8-dihydro-2,5(1H, 6H) quinolinone (SF 349), increase the contractile activity of spontaneously beating and electrically driven atria isolated from rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9998a57e9c368d5cbf457a2312cfac9
https://doi.org/10.1016/s0306-3623(96)00271-6
https://doi.org/10.1016/s0306-3623(96)00271-6