Gastroparesis, Thymoma, and Asymptomatic Myasthenia: A Rare Clinical Scenario

Autor: Consuelo Tamburella, Silvana Parisi, Sara Lillo, Giacomo Ferrantelli, Paola Critelli, Anna Viola, Angelo Platania, Maria Santoro, Alberto Cacciola, Anna Santacaterina, Gianluca Ferini

Publikováno v: Gastroenterology Insights, Vol 13, Iss 1, Pp 27-32 (2022)

Background: Paraneoplastic gastroparesis is a gastrointestinal syndrome that rarely precedes a tumor diagnosis. To increase awareness of this rare clinical entity, we present a case of severe gastroparesis, which was later proven to be associated wit

Externí odkaz: https://doaj.org/article/336919a5632643d9a954cc681e030722

The 'Combo' radiotherapy treatment for high-risk grade 2 meningiomas: dose escalation and initial safety and efficacy analysis

Autor: Antonio Pontoriero, Paola Critelli, Alfredo Conti, Salvatore Cardali, Filippo Flavio Angileri, Antonino Germanò, Sara Lillo, Alessandro Carretta, Anna Brogna, Anna Santacaterina, Silvana Parisi, Stefano Pergolizzi

Publikováno v: Journal of Neuro-Oncology. 161:203-214

The subgroup "high-risk" WHO grade 2 (hRG2) meningiomas may benefit from adjuvant radiation therapy (RT), but results are still suboptimal with high rates of local progression. A dose escalation using high-conformal RT techniques needs to be evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5b569df35b8c9663b68b303b38b192
https://doi.org/10.1007/s11060-022-04107-3

Introducing Radiotherapy in Metastatic Merkel Cell Carcinoma Patients with Limited Progression on Avelumab: An Effective Step against Primary and Secondary Immune Resistance?

Autor: Gianluca Ferini, Valentina Zagardo, Paola Critelli, Anna Santacaterina, Serena Sava, Mandara Muralidhar Harikar, Tejas Venkataram, Giuseppe Emmanuele Umana, Anna Viola, Vito Valenti, Stefano Forte

Publikováno v: Journal of Personalized Medicine. 13:841

Purpose: To investigate the ability of radiotherapy (RT) to prolong progression-free survival (PFS) and to report treatment-related toxicities among oligoprogressive metastatic Merkel cell carcinoma (mMCC) patients on avelumab. Methods: We retrospect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e50ff3cf6ed76e684b9d50e4f2559274
https://doi.org/10.3390/jpm13050841

miR-21 antagonism abrogates Th17 tumor promoting functions in multiple myeloma

Autor: Marco Rossi, Paola Critelli, Caterina Riillo, Nicola Amodio, Bernardo Bertucci, Cirino Botta, Francesco Conforti, Domenica Scumaci, Bruno Paiva, Sarai Sarvide, Marco Gaspari, Pierosandro Tagliaferri, Maria Eugenia Gallo Cantafio, Michelangelo Iannone, Pierfrancesco Tassone, Emanuela Altomare, Maria Teresa Di Martino, Daniele Caracciolo, Nicoletta Polerà, Mariamena Arbitrio, Domenico Taverna

Publikováno v: Leukemia (Basingstoke, Online) (2020). doi:10.1038/s41375-020-0947-1
info:cnr-pdr/source/autori:Marco Rossi; Emanuela Altomare; Cirino Botta; Maria Eugenia Gallo Cantafio; Sarai Sarvide; Daniele Caracciolo; Caterina Riillo; Marco Gaspari; Domenico Taverna; Francesco Conforti; Paola Critelli; Bernardo Bertucci; Michelangelo Iannone; Nicoletta Polerà; Domenica Scumaci; Mariamena Arbitrio; Nicola Amodio; Maria Teresa Di Martino; Bruno Paiva; Pierosandro Tagliaferri; Pierfrancesco Tassone;/titolo:miR-21 antagonism abrogates Th17 tumor promoting functions in multiple myeloma/doi:10.1038%2Fs41375-020-0947-1/rivista:Leukemia (Basingstoke, Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume

Multiple myeloma (MM) is tightly dependent on inflammatory bone marrow microenvironment. IL-17 producing CD4+ T cells (Th17) sustain MM cells growth and osteoclasts-dependent bone damage. In turn, Th17 differentiation relies on inflammatory stimuli.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f11d926913570c25e59a3a64233acd
http://hdl.handle.net/10447/513411

Abstract 4431: Phosphoproteomic analysis of miR-21 modulation in Th17 cells: Potential implications for multiple myeloma bone disease therapy

Autor: Marco Gaspari, Paola Critelli, Annamaria Gullà, Eugenio Morelli, Daniele Caracciolo, Pierfrancesco Tassone, Emanuela Altomare, C. Botta, Nicola Amodio, Pierosandro Tagliaferri, Marco Rossi, Mariamena Arbitrio, Domenica Scumaci, Domenico Taverna

Publikováno v: Cancer Research. 78:4431-4431

Th17 cells play a critical role in Multiple Myeloma (MM) microenvironment by triggering osteoclastogenic activity, that leads to severe skeleton damage. We have recently found that Th17 cells directly promote osteoclast (OCL) differentiation and func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f7d823649729e3022f39d265ac961ef
https://doi.org/10.1158/1538-7445.am2018-4431