Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease

Autor: Dario Besusso 1, 2* Roberta Schellino 3, 4, Marina Boido 3, Sara Belloli 5, 6, Roberta Parolisi 3, Paola Conforti 1, 2, Andrea Faedo 1, Manuel Cernigoj 1, Ilaria Campus 1, Angela Laporta 1, Vittoria Dickinson Bocchi 1, Valentina Murtaj 6, 7, Malin Parmar 10 Paolo Spaiardi 9, Francesca Talpo 9, Claudia Maniezzi 9, Mauro Giuseppe Toselli 9, Gerardo Biella 9, Rosa Maria Moresco 5, 8, Alessandro Vercelli 3, 4 Annalisa Buffo 3, Elena Cattaneo 1

Publikováno v: Stem Cell Reports
Stem Cell Reports 14 (2020): 1–16. doi:10.1016/j.stemcr.2020.03.018
info:cnr-pdr/source/autori:Dario Besusso 1,2* Roberta Schellino 3,4*, Marina Boido 3,4, Sara Belloli 5,6, Roberta Parolisi 3,4, Paola Conforti 1,2, Andrea Faedo 1,2,11, Manuel Cernigoj 1,2, Ilaria Campus 1,2, Angela Laporta 1,2, Vittoria Dickinson Bocchi 1,2, Valentina Murtaj 6,7, Malin Parmar 10 Paolo Spaiardi 9, Francesca Talpo 9, Claudia Maniezzi 9, Mauro Giuseppe Toselli 9, Gerardo Biella 9, Rosa Maria Moresco 5,6,8, Alessandro Vercelli 3,4 Annalisa Buffo 3,4 and Elena Cattaneo 1,2/titolo:Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease./doi:10.1016%2Fj.stemcr.2020.03.018/rivista:Stem Cell Reports/anno:2020/pagina_da:1/pagina_a:16/intervallo_pagine:1–16/volume:14

Summary Huntington disease (HD) is an inherited late-onset neurological disorder characterized by progressive neuronal loss and disruption of cortical and basal ganglia circuits. Cell replacement using human embryonic stem cells may offer the opportu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5634e95abd3cbc8468dd02edd0c9374a
http://hdl.handle.net/10281/272196