Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Paola Canale"'
Autor:
Paola Canale, Andrea Borghini
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6620 (2024)
MicroRNAs (miRNAs) are small non-coding RNAs that play an important role by controlling gene expression in the cytoplasm in almost all biological pathways. Recently, scientists discovered that miRNAs are also found within mitochondria, the energy-pro
Externí odkaz:
https://doaj.org/article/3a8ccc983b9e457ba6ba46cff050e751
Autor:
Andrea Borghini, Rudina Ndreu, Paola Canale, Jonica Campolo, Irene Marinaro, Antonella Mercuri, Stefano Turchi, Maria Grazia Andreassi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1428 (2024)
Telomere shortening, chromosomal damage, and mitochondrial dysfunction are major initiators of cell aging and biomarkers of many diseases. However, the underlying correlations between nuclear and mitochondrial DNA alterations remain unclear. We inves
Externí odkaz:
https://doaj.org/article/58ac761fa0f9453ea91e503f9f144141
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3211 (2023)
Telomere dysfunction is implicated in vascular aging and shorter leucocyte telomeres are associated with an increased risk of atherosclerosis, myocardial infarction, and heart failure. Another pathophysiological mechanism that explains the causal rel
Externí odkaz:
https://doaj.org/article/9913aa96cdb44f34b87d518b74bc2d86
Ultrastructural and Molecular Investigation on Peripheral Leukocytes in Alzheimer’s Disease Patients
Autor:
Roberta Giannelli, Paola Canale, Renata Del Carratore, Alessandra Falleni, Margherita Bernardeschi, Francesca Forini, Elisa Biagi, Olivia Curzio, Paolo Bongioanni
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7909 (2023)
Thriving literature underlines white blood cell involvement in the inflammatory processes of Alzheimer’s Disease (AD). Among leukocytes, lymphocytes have been considered sentinels of neuroinflammation for years, but recent findings highlighted the
Externí odkaz:
https://doaj.org/article/fb44612937234c2989befefa803285c9
Autor:
Andrea Baldini, Alberto Greco, Mirko Lomi, Roberta Giannelli, Paola Canale, Andrea Diana, Cristina Dolciotti, Renata Del Carratore, Paolo Bongioanni
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13289 (2022)
Alzheimer’s disease (AD) is the leading cause of dementia, but the pathogenetic factors are not yet well known, and the relationships between brain and systemic biochemical derangements and disease onset and progression are unclear. We aim to focus
Externí odkaz:
https://doaj.org/article/6b40b982a5c345c2aec22d11db14584e
Autor:
Paola Canale, Giuseppina Nicolini, Letizia Pitto, Claudia Kusmic, Milena Rizzo, Silvana Balzan, Giorgio Iervasi, Francesca Forini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6549 (2022)
The opening of the ATP-sensitive mitochondrial potassium channel (mitok-ATP) is a common goal of cardioprotective strategies in the setting of acute and chronic myocardial disease. The biologically active thyroid hormone (TH), 3-5-3-triiodothyronine
Externí odkaz:
https://doaj.org/article/e18834547f8c416aba3ca5ea96eba395
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7154 (2022)
The available evidence indicates a close connection between gut microbiota (GM) disturbance and increased risk of cardiometabolic (CM) disorders and cardiovascular (CV) disease. One major objective of this narrative review is to discuss the key contr
Externí odkaz:
https://doaj.org/article/7fa9e425700a4c05abf61f308ec277f7
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1122 (2020)
Cardiovascular disease (CVD) represents a major threat for human health. The available preventive and treatment interventions are insufficient to revert the underlying pathological processes, which underscores the urgency of alternative approaches. M
Externí odkaz:
https://doaj.org/article/9f41eae4ead54dd58a00e2ffefa583e2
Publikováno v:
Cardiac Electrophysiology Clinics. 14:21-28
Publikováno v:
Cardiac Electrophysiology Clinics
Coronavirus-19 disease (COVID-19) affects more people than previous coronavirus infections, namely Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) and has a higher mortality. Higher incidence and mortality can pro