Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Paola Caccin"'
Hydrogel-in-hydrogel live bioprinting for guidance and control of organoids and organotypic cultures
Autor:
Anna Urciuolo, Giovanni Giuseppe Giobbe, Yixiao Dong, Federica Michielin, Luca Brandolino, Michael Magnussen, Onelia Gagliano, Giulia Selmin, Valentina Scattolini, Paolo Raffa, Paola Caccin, Soichi Shibuya, Dominic Scaglioni, Xuechun Wang, Ju Qu, Marko Nikolic, Marco Montagner, Gabriel L. Galea, Hans Clevers, Monica Giomo, Paolo De Coppi, Nicola Elvassore
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Three-dimensional hydrogel-based organ-like cultures can be applied to study development, regeneration, and disease in vitro. However, the control of engineered hydrogel composition, mechanical properties and geometrical constraints tends to
Externí odkaz:
https://doaj.org/article/8d949ed909e143ba8263b25ad3233dc1
Autor:
Edoardo Maghin, Eugenia Carraro, Daniele Boso, Arben Dedja, Mattia Giagante, Paola Caccin, Raluca Ana-Maria Barna, Silvia Bresolin, Alice Cani, Giulia Borile, Deborah Sandrin, Filippo Romanato, Francesca Cecchinato, Anna Urciuolo, Dorianna Sandonà, Paolo De Coppi, Piero G. Pavan, Martina Piccoli
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract The production of skeletal muscle constructs useful for replacing large defects in vivo, such as in congenital diaphragmatic hernia (CDH), is still considered a challenge. The standard application of prosthetic material presents major limita
Externí odkaz:
https://doaj.org/article/1bbd983d9cd5431fa103f3f36913e3b0
Autor:
Paolo Raffa, Valentina Scattolini, Mattia Francesco Maria Gerli, Silvia Perin, Meihua Cui, Paolo De Coppi, Nicola Elvassore, Paola Caccin, Camilla Luni, Anna Urciuolo
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 10, Pp 1233-1243 (2020)
Abstract Skeletal muscle decellularization allows the generation of natural scaffolds that retain the extracellular matrix (ECM) mechanical integrity, biological activity, and three‐dimensional (3D) architecture of the native tissue. Recent reports
Externí odkaz:
https://doaj.org/article/2958a840477c4d71a2a6a195d6d1d41a
Autor:
Caterina Trevisan, Mario Enrique Alvrez Fallas, Edoardo Maghin, Chiara Franzin, Piero Pavan, Paola Caccin, Angela Chiavegato, Eugenia Carraro, Daniele Boso, Francesco Boldrin, Federico Caicci, Enrica Bertin, Luca Urbani, Anna Milan, Carlo Biz, Lorenza Lazzari, Paolo De Coppi, Michela Pozzobon, Martina Piccoli
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 858-869 (2019)
Abstract Surgical repair of large muscular defects requires the use of autologous graft transfer or prosthetic material. Naturally derived matrices are biocompatible materials obtained by tissue decellularization and are commonly used in clinical pra
Externí odkaz:
https://doaj.org/article/0c15f6c5e94d46a09d8dc058cfbfa131
Autor:
Paolo Raffa, Maria Easler, Francesca Cecchinato, Beatrice Auletta, Valentina Scattolini, Silvia Perin, Mattia Francesco Maria Gerli, Paola Caccin, Nicola Elvassore, Paolo De Coppi, Anna Urciuolo
Publikováno v:
Applied Sciences, Vol 11, Iss 20, p 9485 (2021)
Decellularized skeletal muscle (dSkM) constructs have received much attention in recent years due to the versatility of their applications in vitro. In search of adequate in vitro models of the skeletal muscle tissue, the dSkM offers great advantages
Externí odkaz:
https://doaj.org/article/f8d4b14ffb4c44e8800558059f7f07b0
Publikováno v:
Bio-Protocol, Vol 8, Iss 5 (2018)
The neuromuscular junction (NMJ) is the specialized synapse by which peripheral motor neurons innervate muscle fibers and control skeletal muscle contraction. The NMJ is the target of several xenobiotics, including chemicals, plant, animal and bacter
Externí odkaz:
https://doaj.org/article/569fdbc965ba4c8a9397a93670f6c395
Autor:
Paola Caccin, Michele Scorzeto, Nunzio Damiano, Oriano Marin, Aram Megighian, Cesare Montecucco
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 388-396 (2015)
Synaptotagmin is a synaptic vesicle membrane protein which changes conformation upon Ca2+ binding and triggers the fast neuroexocytosis that takes place at synapses. We have synthesized a series of peptides corresponding to the sequence of the cytoso
Externí odkaz:
https://doaj.org/article/3cbbef19d0814f65983a51901b89bc91
Autor:
Irene Zornetta, Paola Caccin, Julián Fernandez, Bruno Lomonte, José María Gutierrez, Cesare Montecucco
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 2, p e1526 (2012)
Skeletal muscle necrosis is a common manifestation of viperid snakebite envenomations. Venoms from snakes of the genus Bothrops, such as that of B. asper, induce muscle tissue damage at the site of venom injection, provoking severe local pathology wh
Externí odkaz:
https://doaj.org/article/03e25ab5303146c6b380a9c587048e9c
Autor:
Pompeo Volpe, Alessandra Bosutti, Alessandra Nori, Riccardo Filadi, Gaia Gherardi, Gabor Trautmann, Sandra Furlan, Gabriele Massaria, Marina Sciancalepore, Aram Megighian, Paola Caccin, Annalisa Bernareggi, Michele Salanova, Roberta Sacchetto, Dorianna Sandonà, Paola Pizzo, Paola Lorenzon
Publikováno v:
Journal of General Physiology. 154
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are enriched at postsynaptic membrane compartments of the neuromuscular junction (NMJ), surrounding the subsynaptic nuclei and close to nicotinic acetylcholine receptors (nAChRs) of the motor endplate. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d99e75b31646d7906a2e86018d2215
https://doi.org/10.1085/jgp.202213128
https://doi.org/10.1085/jgp.202213128
Autor:
Michela Bondì, Roberta Sacchetto, Marcello Carotti, Alberto Benetollo, Dorianna Sandonà, Bert Blaauw, Martina Scano, Eylem Emek Akyurek, Michela Soardi, Sandra Furlan, Paola Caccin, Leonardo Nogara, Francesco Dalla Barba
Limb-girdle muscular dystrophy R3 (LGMDR3) is caused by mutations in the SGCA gene coding for α-sarcoglycan (SG). Together with β- γ- and δ-SG, α-SG forms a tetramer embedded in the dystrophin associated protein complex crucial for protecting th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db33b7e45a43a1f7e1b4fbfecbf0adb
http://hdl.handle.net/11577/3400586
http://hdl.handle.net/11577/3400586
