Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Paola Bontempo"'
Autor:
Benluvankar Varghese, Ugo Chianese, Lucia Capasso, Veronica Sian, Paola Bontempo, Mariarosaria Conte, Rosaria Benedetti, Lucia Altucci, Vincenzo Carafa, Angela Nebbioso
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Cancer cells are characterized by uncontrolled cell proliferation and impaired bioenergetics. Sirtuins are a family of highly conserved enzymes that play a fundamental role in energy metabolism regulation. SIRT1, in particular, dr
Externí odkaz:
https://doaj.org/article/fc21522b9cb640cb8ae0a88b393f320a
Autor:
Monica Scognamiglio, Viviana Maresca, Adriana Basile, Severina Pacifico, Antonio Fiorentino, Maurizio Bruno, Natale Badalamenti, Marta Kapelusz, Pasquale Marino, Lucia Capasso, Paola Bontempo, Giuseppe Bazan
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 402 (2024)
The use of Nigella damascena seeds in the culinary field or as aerial parts infusions in the pharmaceutical and cosmetic fields is widely reported. The biological activity of this plant, as demonstrated over the years, is closely related to its phyto
Externí odkaz:
https://doaj.org/article/36d5d3977d134b4fb33ce56ddb572805
Autor:
Teresa Infante, Monica Franzese, Antonio Ruocco, Concetta Schiano, Ornella Affinito, Katia Pane, Domenico Memoli, Francesca Rizzo, Alessandro Weisz, Paola Bontempo, Vincenzo Grimaldi, Liberato Berrino, Andrea Soricelli, Ciro Mauro, Claudio Napoli
Publikováno v:
Epigenetics, Vol 17, Iss 5, Pp 547-563 (2022)
Acute coronary syndrome (ACS) is the most severe clinical manifestation of coronary heart disease. We performed an epigenome-wide analysis of circulating CD4+ and CD8+ T cells isolated from ACS patients and healthy subjects (HS), enrolled in the DIAN
Externí odkaz:
https://doaj.org/article/91ad99c7794d4348aa5cd12448a31186
Autor:
Deborah Giordano, Bernardina Scafuri, Luigi De Masi, Lucia Capasso, Viviana Maresca, Lucia Altucci, Angela Nebbioso, Angelo Facchiano, Paola Bontempo
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1624 (2023)
Epigenetic mechanisms finely regulate gene expression and represent potential therapeutic targets. Cambinol is a synthetic heterocyclic compound that inhibits class III histone deacetylases known as sirtuins (SIRTs). The acetylating action that resul
Externí odkaz:
https://doaj.org/article/1fc1cc3f519e4798a9c3155b98182a52
Autor:
Viviana Maresca, Natale Badalamenti, Vincenzo Ilardi, Maurizio Bruno, Paola Bontempo, Adriana Basile
Publikováno v:
Plants, Vol 11, Iss 24, p 3529 (2022)
The chemical profile of the essential oil (EO) of the aerial parts of Thymus leucotrichus var. creticus (Lamiaceae), a taxon not previously studied, was investigated by GC–MS analysis, using a DB–Wax polar column. Oxygenated monoterpenes and mono
Externí odkaz:
https://doaj.org/article/3e12493c71024ea9b9b86f556444517c
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 568 (2020)
Histone modifications through acetylation are fundamental for remodelling chromatin and consequently activating gene expression. The imbalance between acetylation and deacetylation activity causes transcriptional dysregulation associated with several
Externí odkaz:
https://doaj.org/article/b1b99fae6b73416f8ede5b365d820151
Autor:
Paola Bontempo, Luigi De Masi, Vincenzo Carafa, Daniela Rigano, Lucia Scisciola, Concetta Iside, Roberto Grassi, Anna Maria Molinari, Riccardo Aversano, Angela Nebbioso, Domenico Carputo, Lucia Altucci
Publikováno v:
Journal of Functional Foods, Vol 19, Iss , Pp 584-593 (2015)
The action of anthocyanins contained in the Vitelotte potato (Solanum tuberosum L.) in both breast and haematological cancers were investigated. The biomedical activities of anthocyanin extract derived from the Vitelotte cultivar were determined. Mol
Externí odkaz:
https://doaj.org/article/e79f972ed5174a8a9d3e19a418b66f37
Autor:
Luigi De Masi, Paola Bontempo, Daniela Rigano, Paola Stiuso, Vincenzo Carafa, Angela Nebbioso, Sonia Piacente, Paola Montoro, Riccardo Aversano, Vincenzo D’Amelia, Domenico Carputo, Lucia Altucci
Publikováno v:
Molecules, Vol 25, Iss 1, p 233 (2020)
Plants produce a vast array of biomolecules with beneficial effects for human health. In this study, polyphenol and anthocyanin-rich extracts (PAE) from pigmented tubers of Solanum tuberosum L. varieties “Blue Star”, “Magenta Love”, and “Do
Externí odkaz:
https://doaj.org/article/dde1ab2dea5e4096be568929f99882f9
Autor:
Giuditta Benincasa, Bradley A. Maron, Ornella Affinito, Michele D’Alto, Monica Franzese, Paola Argiento, Concetta Schiano, Emanuele Romeo, Paola Bontempo, Paolo Golino, Liberato Berrino, Joseph Loscalzo, Claudio Napoli
Publikováno v:
Journal of Cardiovascular Translational Research. 16:17-30
Pathogenic DNA methylation changes may be involved in pulmonary arterial hypertension (PAH) onset and its progression, but there is no data on potential associations with patient-derived hemodynamic parameters. The reduced representation bisulfite se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1667118912afeda185d1e2da605899fc
https://doi.org/10.1007/s12265-022-10294-1
https://doi.org/10.1007/s12265-022-10294-1
Autor:
Piergiorgio Cianciullo, Francesca Cimmino, Viviana Maresca, Sergio Sorbo, Paola Bontempo, Adriana Basile
Publikováno v:
Applied Biosciences. 1:73-94
Bryophytes are a poorly studied group of land plants that have been used in traditional medicine as a multipurpose remedy for centuries. Due to their peculiar morphology and physiology, bryophytes synthesise a multitude of secondary metabolites with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d2ab614b9b64850b5ee76c4a90b1f9e
https://doi.org/10.3390/applbiosci1010005
https://doi.org/10.3390/applbiosci1010005