Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Paola Bonaventura"'
Autor:
Vincent Alcazer, Christophe Caux, Paola Bonaventura, Virginie Mutez, Laurie Tonon, Juliette Martin, Nicolas Chuvin, Rasha Boulos, Yann Estornes, Jenny Valladeau-Guilemond, Alain Viari, Stephane Depil
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/1971042d72dc40ba99cf34aa19eb2116
Autor:
Paola Bonaventura, Guillaume Courbon, Aline Lamboux, Fabien Lavocat, Hubert Marotte, Francis Albarède, Pierre Miossec
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Synovium hyperplasia characterizes joint diseases, such as rheumatoid arthritis (RA). The cytotoxic effect of low-dose Cadmium (Cd) was tested in vitro and ex vivo on synoviocytes, the mesenchymal key effector cells of inflammation and proli
Externí odkaz:
https://doaj.org/article/ccdcf8d233f943d282a6462b0e13a530
Autor:
Paola Bonaventura, Tala Shekarian, Vincent Alcazer, Jenny Valladeau-Guilemond, Sandrine Valsesia-Wittmann, Sebastian Amigorena, Christophe Caux, Stéphane Depil
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Therapeutic monoclonal antibodies targeting immune checkpoints (ICPs) have changed the treatment landscape of many tumors. However, response rate remains relatively low in most cases. A major factor involved in initial resistance to ICP inhibitors is
Externí odkaz:
https://doaj.org/article/f5194aaa4fd842d8b84b2a03d16652fb
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196285 (2018)
Interleukin-1-beta (IL-1β) and tumour necrosis factor-alpha (TNF-α) are both monocyte-derived cytokines. Both cytokines have been previously described to exert a role in rheumatoid arthritis (RA) pathogenesis synergizing with other pro-inflammatory
Externí odkaz:
https://doaj.org/article/994af103a86c4e7ca8d91946d8514ae9
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180879 (2017)
Zinc (Zn) has major effects on immune system activation while Cadmium (Cd) has anti-inflammatory and anti-proliferative effects in several chronic inflammatory contexts. The aim of this work was to investigate by which mechanisms Zn could compete wit
Externí odkaz:
https://doaj.org/article/c4dbe3092d0d40d686371a40ecd29319
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147146 (2016)
OBJECTIVE:Zinc (Zn) has major effects on the immune system and inflammation is associated with systemic Zn deficiency. The aim of this work was to investigate how inflammation modifies Zn metabolism at the cellular level. Rheumatoid arthritis (RA) sy
Externí odkaz:
https://doaj.org/article/acfa3db042264e768fbd9b4c0e2687c4
Autor:
Marion Mallet, Rasha E. Boulos, Vincent Alcazer, Paola Bonaventura, Yann Estornes, Nicolas Chuvin, Stéphane Depil
Publikováno v:
European Journal of Cancer. 171:96-105
Cancer vaccines and T-cell receptor (TCR) engineered T cells (Tg-T cell) represent two different therapeutic strategies that can target the same tumour epitopes. The first approach requires the induction of a specific immune response in patients, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e342bd1c72a4a6d8fa0a20ba5d183c2b
https://doi.org/10.1016/j.ejca.2022.05.008
https://doi.org/10.1016/j.ejca.2022.05.008
Autor:
Paola Bonaventura, Vincent Alcazer, Virginie Mutez, Laurie Tonon, Juliette Martin, Nicolas Chuvin, Emilie Michel, Rasha E. Boulos, Yann Estornes, Jenny Valladeau-Guilemond, Alain Viari, Qing Wang, Christophe Caux, Stéphane Depil
Publikováno v:
Science Advances. 8
Human endogenous retroviruses (HERVs) represent 8% of the human genome. HERV products may represent tumor antigens relevant for cancer immunotherapy. We developed a bioinformatic approach to identify shared CD8 + T cell epitopes derived from cancer-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7850b610cc0357714d4e7003c3338c
https://doi.org/10.1126/sciadv.abj3671
https://doi.org/10.1126/sciadv.abj3671
Autor:
Vincent Alcazer, Paola Bonaventura, Laurie Tonon, Emilie Michel, Virginie Mutez, Clémentine Fabres, Nicolas Chuvin, Rasha Boulos, Yann Estornes, Véronique Maguer‐Satta, Kevin Geistlich, Alain Viari, Klaus H. Metzeler, Wolfgang Hiddemann, Aarif M. N. Batch, Tobias Herold, Christophe Caux, Stéphane Depil
Publikováno v:
American Journal of Hematology
American Journal of Hematology, 2022, 97 (9), pp.1200-1214. ⟨10.1002/ajh.26647⟩
American Journal of Hematology, 2022, 97 (9), pp.1200-1214. ⟨10.1002/ajh.26647⟩
International audience; Human endogenous retroviruses (HERVs) represent 8% of the human genome. The expression of HERVs and their immune impact have not been extensively studied in Acute Myeloid Leukemia (AML). In this study, we used a reference of 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f35f4f7ab81d9aa71a1e1f4474a8bc
https://hal.science/hal-03855460
https://hal.science/hal-03855460
Autor:
Paola Bonaventura, Vincent Alcazer, Virginie Mutez, Laurie Tonon, Juliette Martin, Nicolas Chuvin, Emilie Michel, Rasha Boulos, Yann Estornes, Jenny Valladeau-Guilemond, Alain Viari, Quing Wang, Christophe Caux, Stephane Depil
Publikováno v:
Cancer Immunology Research. 10:B49-B49
Human endogenous retroviruses (HERVs) represent 8% of the human genome. HERVs are silenced by epigenetic mechanisms in normal cells but are aberrantly expressed by tumor cells. Given their viral origin, HERV products may represent tumor antigens rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4d551e039daa2e6dcaf45b8285db928
https://doi.org/10.1158/2326-6074.tumimm22-b49
https://doi.org/10.1158/2326-6074.tumimm22-b49