Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Paola Bezzi"'
Autor:
Laura Ferrucci, Bernadette Basilico, Ingrid Reverte, Francesca Pagani, Giorgia Scaringi, Federica Cordella, Barbara Cortese, Gaia De Propris, Andrea Galeone, Letizia Mazzarella, Alessandro Mormino, Stefano Garofalo, Azka Khan, Valeria De Turris, Valentina Ferretti, Paola Bezzi, Cornelius Gross, Daniele Caprioli, Cristina Limatola, Silvia Di Angelantonio, Davide Ragozzino
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
It is widely acknowledged that microglia actively regulate synaptic function in the brain. Remarkably, much of our understanding regarding the role of microglia in synaptic regulation is derived from studies in acute brain slices. However, it is stil
Externí odkaz:
https://doaj.org/article/7877931d38ff4d38a89345630bb29269
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by elusive underlying mechanisms. Recent attention has focused on the involvement of astrocytes and microglia in ASD pathology. These glial cells play pivotal role
Externí odkaz:
https://doaj.org/article/b2e69c9bb3d44627b25390a2a0010c3a
Autor:
Patrizia Ratano, Germana Cocozza, Cecilia Pinchera, Ludovica Maria Busdraghi, Iva Cantando, Katiuscia Martinello, Mariarosaria Scioli, Maria Rosito, Paola Bezzi, Sergio Fucile, Heike Wulff, Cristina Limatola, Giuseppina D’Alessandro
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no effective therapy, causing progressive loss of motor neurons in the spinal cord, brainstem, and motor cortex. Regardless of its genetic or sporadic origin, there is curr
Externí odkaz:
https://doaj.org/article/7b0c83b8d0b3491eaf2f6c242eacace9
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/2e133719f0be415b876a66b467fbdf3a
Autor:
Laura Ferrucci, Iva Cantando, Federica Cordella, Silvia Di Angelantonio, Davide Ragozzino, Paola Bezzi
Publikováno v:
Cells, Vol 12, Iss 24, p 2827 (2023)
Synapses are the fundamental structures of neural circuits that control brain functions and behavioral and cognitive processes. Synapses undergo formation, maturation, and elimination mainly during postnatal development via a complex interplay with n
Externí odkaz:
https://doaj.org/article/de923b5b32734ad083310e5022def9e3
Autor:
Federica Cordella, Laura Ferrucci, Chiara D’Antoni, Silvia Ghirga, Carlo Brighi, Alessandro Soloperto, Ylenia Gigante, Davide Ragozzino, Paola Bezzi, Silvia Di Angelantonio
Publikováno v:
Life, Vol 12, Iss 11, p 1884 (2022)
Maintaining the excitability of neurons and circuits is fundamental for healthy brain functions. The global compensatory increase in excitatory synaptic strength, in response to decreased activity, is one of the main homeostatic mechanisms responsibl
Externí odkaz:
https://doaj.org/article/e1710a768b27486dae22e28491f06bb6
Autor:
Tamara Zehnder, Francesco Petrelli, Jennifer Romanos, Eva C. De Oliveira Figueiredo, Tommy L. Lewis, Jr., Nicole Déglon, Franck Polleux, Mirko Santello, Paola Bezzi
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108952- (2021)
Summary: The mechanisms controlling the post-natal maturation of astrocytes play a crucial role in ensuring correct synaptogenesis. We show that mitochondrial biogenesis in developing astrocytes is necessary for coordinating post-natal astrocyte matu
Externí odkaz:
https://doaj.org/article/f1df3debacce4887983091ca5960c352
Autor:
Alberto Azzalin, Francesca Brambilla, Eloisa Arbustini, Katia Basello, Attilio Speciani, Pierluigi Mauri, Paola Bezzi, Lorenzo Magrassi
Publikováno v:
Cells, Vol 9, Iss 5, p 1249 (2020)
Adaptation of glioblastoma to caloric restriction induces compensatory changes in tumor metabolism that are incompletely known. Here we show that in human glioblastoma cells maintained in exhausted medium, SHC adaptor protein 3 (SHC3) increases due t
Externí odkaz:
https://doaj.org/article/4cfc31f7fb3c4015820e036756e306a9
Publikováno v:
Neural Plasticity, Vol 2014 (2014)
Astrocytes are highly secretory cells, participating in rapid brain communication by releasing glutamate. Recent evidences have suggested that this process is largely mediated by Ca2+-dependent regulated exocytosis of VGLUT-positive vesicles. Here by
Externí odkaz:
https://doaj.org/article/f1f742379d3345f4b506c925f26c3fa6
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87758 (2014)
Pancreatic β-cells play central roles in blood glucose homeostasis. Beside insulin, these cells release neurotransmitters and other signaling molecules stored in synaptic-like microvesicles (SLMVs). We monitored SLMV exocytosis by transfecting a syn
Externí odkaz:
https://doaj.org/article/f0c88f981eca485682a112e8162bb25d