Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Paola Acosta"'
Autor:
Jorge Trilleras, Andrés Charris-Molina, Alfredo Pérez-Gamboa, Paola Acosta-Guzman, Jairo Quiroga
Publikováno v:
Royal Society Open Science, Vol 11, Iss 3 (2024)
Ultrasound-assisted synthesis of pyrimidoquinolindione derivatives via a multicomponent reaction and subsequent formylation with Vilsmeier–Haack reagent were performed. Compounds were prepared by a one-pot method from aminopyrimidinones, dimedon
Externí odkaz:
https://doaj.org/article/b9c9f79adeaf407a893fd8a56f34d779
Publikováno v:
Informatics in Medicine Unlocked, Vol 45, Iss , Pp 101464- (2024)
Rheumatoid arthritis is a chronic autoimmune illness characterized by joint dysfunction. New drugs are available, among them Janus Kinase enzyme inhibitor drugs, whose significant side effects are associated with neutropenia, thrombocytopenia, and dy
Externí odkaz:
https://doaj.org/article/33e9b557ab244eebb03544543aba80a5
Autor:
Victoria Fonseca-Benítez, Paola Acosta-Guzmán, Juan Esteban Sánchez, Zaira Alarcón, Ronald Andrés Jiménez, James Guevara-Pulido
Publikováno v:
Molecules, Vol 29, Iss 8, p 1802 (2024)
Breast cancer is a major global health issue, causing high incidence and mortality rates as well as psychological stress for patients. Chemotherapy resistance is a common challenge, and the Aldo-keto reductase family one-member C3 enzyme is associate
Externí odkaz:
https://doaj.org/article/fadba12a6f8844bb80ba5039815c81e6
Autor:
Lilia Jadith Bernal-Cepeda, Ronald Andrés Jiménez, Myriam L. Velandia-Romero, Paola Acosta-Guzmán, Jaime E. Castellanos
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 355 (2024)
The modulation of TRPV1 emerges as a promising strategy for dental pain management. This study aimed to assess TRPV1 modulation in a human odontoblast-like cell model using Capsazepine (CZP) loaded in a nanogel delivery system. Gelatin nanogels, synt
Externí odkaz:
https://doaj.org/article/8b8281553ada4cd5ba14daeca6d27334
Publikováno v:
Groningen Journal of International Law, Vol 6, Iss 1, Pp 128-145 (2018)
The role of national judges in international law is still an undecided subject matter. Most scholars consider the decisions from national judges merely as acts of States, denying the possibility that those judgments constitute an autonomous source of
Externí odkaz:
https://doaj.org/article/9f392b44497d4fdfa2fb9f447d79f311
Publikováno v:
Educação (Santa Maria. Online), Vol 42, Iss 3, Pp 505-520 (2017)
Las recientes iniciativas oficiales dirigidas al profesor buscan impregnar de nuevos principios, estrategias e instrumentos su desempeño. Pero se trata de significados que buscan desplegarse sobre contextos diversos, colmados de tradiciones que no n
Externí odkaz:
https://doaj.org/article/1388845c6de44e608388c34b0ad1a51f
Publikováno v:
Civilizar, Vol 19, Iss 37 (2019)
Este artículo analiza y discute la naturaleza del proceso de gentrificación rururbana que se está desarrollando en la vereda La Florida en Villamaría (Caldas) y la vereda Clarete (Popayán, Cauca), Colombia. Los casos examinados permiten una revi
Externí odkaz:
https://doaj.org/article/7cc346a12401423ca8547fdf580ebdce
Autor:
Paola Acosta, Braulio Insuasty, Alejandro Ortiz, Rodrigo Abonia, Maximiliano Sortino, Susana A. Zacchino, Jairo Quiroga
Publikováno v:
Arabian Journal of Chemistry, Vol 9, Iss 3, Pp 481-492 (2016)
Novel fused pyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidines 5 were prepared by a solvent-free microwave assisted reaction of heterocyclic o-aminonitriles 3 and cyanopyridines 4 in the presence of tBuOK as catalyst. This protocol provides a versatile
Externí odkaz:
https://doaj.org/article/1eada2b1f24d4c299556cc507ef3622f
Autor:
Paola Acosta, Estefanía Butassi, Braulio Insuasty, Alejandro Ortiz, Rodrigo Abonia, Susana A. Zacchino, Jairo Quiroga
Publikováno v:
Molecules, Vol 20, Iss 5, Pp 8499-8520 (2015)
The microwave assisted reaction between heterocyclic o-aminonitriles 1 and cyclic ketones 2 catalyzed by zinc chloride led to new series of pyrazolo[3,4-b] [1,8]naphthyridin-5-amines 3 in good yields. This procedure provides several advantages such a
Externí odkaz:
https://doaj.org/article/94013a406da44122b2075f034cd617f4
Publikováno v:
Molecules, Vol 23, Iss 9, p 2382 (2018)
Amides are undeniably some of the most important compounds in Nature and the chemical industry, being present in biomolecules, materials, pharmaceuticals and many other substances. Unfortunately, the traditional synthesis of amides suffers from some
Externí odkaz:
https://doaj.org/article/98127d47c8f444e8b0554fdaaebf7e54