Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Paola A. Bignone"'
Autor:
Jieun Lee, Hal Sternberg, Paola A. Bignone, James Murai, Nafees N. Malik, Michael D. West, Dana Larocca
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2777 (2023)
Human pluripotent stem cells (hPSCs) can be used as a renewable source of endothelial cells for treating cardiovascular disease and other ischemic conditions. Here, we present the derivation and characterization of a panel of distinct clonal embryoni
Externí odkaz:
https://doaj.org/article/269729a49bdb47699db95e0c100afad9
Publikováno v:
Biochemical and Biophysical Research Communications. 525:563-569
Supercentenarians (≥110-year-old, SC) are a uniquely informative population not only because they surpass centenarians in age, but because they appear to age more slowly with fewer incidences of chronic age-related disease than centenarians. We rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da2d5a4c73aaf78790116293bb2ebce
https://doi.org/10.1016/j.bbrc.2020.02.092
https://doi.org/10.1016/j.bbrc.2020.02.092
Autor:
Paola A Bignone, Rachel A Krupa, Hal Sternberg, Walter D Funk, Evan Y Snyder, Michael D West, David Larocca
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58200 (2013)
Human pluripotent stem (hPS) cells are capable of differentiation into derivatives of all three primary embryonic germ layers and can self-renew indefinitely. They therefore offer a potentially scalable source of replacement cells to treat a variety
Externí odkaz:
https://doaj.org/article/061612bc82f74effa5a468876d1e4e4c
Publikováno v:
Signal Transduction. 7:225-239
The p90 ribosomal S6 kinase (RPS6KA1-6; RSK1-6) family represents an important family of conserved serine-threonine kinases among the higher eukaryotes. RSKs are identified by the presence of two non-identical and active kinase domains that is unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba3a010ebec107058576cb34131bcc96
https://doi.org/10.1002/sita.200600091
https://doi.org/10.1002/sita.200600091
Autor:
Gracy Emilion, Paola A. Bignone, Stephan Beck, J Finch, Ying Liu, Andrew J. Mungall, Ian Dunham, Trivadi S. Ganesan, Ashley Edward Roy Soosay, F. M.L. Charnock, Kwok Y. Lee
Publikováno v:
Oncogene. 26:683-700
We had previously defined by allele loss studies a minimal region at 6q27 (between D6S264 and D6S297) to contain a putative tumour suppressor gene. The p90 ribosomal S6 kinase-3 gene (p90 Rsk-3, RPS6KA2) maps in this interval. It is a serine-threonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc0206231be8cc9ed3ea9ac93d94eb9
https://doi.org/10.1038/sj.onc.1209827
https://doi.org/10.1038/sj.onc.1209827
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1357
The ability of human pluripotent stem cells (hPS) to both self-renew and differentiate into virtually any cell type makes them a promising source of cells for cell-based regenerative therapies. However, stem cell identity, purity, and scalability rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36d6a51669cc07a890e388fe2ab12df2
https://pubmed.ncbi.nlm.nih.gov/25410289
https://pubmed.ncbi.nlm.nih.gov/25410289
Publikováno v:
Methods in Molecular Biology ISBN: 9781493930548
The ability of human pluripotent stem cells (hPS) to both self-renew and differentiate into virtually any cell type makes them a promising source of cells for cell-based regenerative therapies. However, stem cell identity, purity, and scalability rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64cfc556b099c8bb33daca5690dd2a9e
https://doi.org/10.1007/7651_2014_144
https://doi.org/10.1007/7651_2014_144
Autor:
Rachel Krupa, Michael D. West, Walter D. Funk, Evan Y. Snyder, Paola A. Bignone, Hal Sternberg, David Larocca
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58200 (2013)
PLoS ONE, Vol 8, Iss 3, p e58200 (2013)
Human pluripotent stem (hPS) cells are capable of differentiation into derivatives of all three primary embryonic germ layers and can self-renew indefinitely. They therefore offer a potentially scalable source of replacement cells to treat a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a503aabb4815d0c9236c113a18af9c2
http://europepmc.org/articles/PMC3587414
http://europepmc.org/articles/PMC3587414
Autor:
Alison H. Banham, Rosalind Launchbury, Philip J. Brown, Linden Lyne, Giovanna Roncador, Paola A. Bignone, Kevin C. Gatter, Rajko Kusec, Andrew J. Campbell, Charles H. Lawrie, Jianxiang Chi
FOXP2 mutation causes a severe inherited speech and language defect, while the related transcription factors FOXP1, FOXP3 and FOXP4 are implicated in cancer. FOXP2 mRNA and protein expression were characterised in normal human tissues, haematological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad121cc8a4979bf47abcd79cb82ff656
https://www.bib.irb.hr/541485
https://www.bib.irb.hr/541485
Autor:
Anthony J. Baines, Alison M. Maggs, Gareth W. Phillips, Mikayala D.A. King, Jennifer C. Pinder, Pauline M. Bennett, Paola A. Bignone
Publikováno v:
Molecular biology and evolution. 26(9)
We describe a structural domain common to proteins related to human calmodulin-regulated spectrin-associated protein1 (CAMSAP1). Analysis of the sequence of CAMSAP1 identified a domain near the C-terminus common to CAMSAP1 and two other mammalian pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5d693bbcfd027e26c1085acdcdb076
https://pubmed.ncbi.nlm.nih.gov/19508979
https://pubmed.ncbi.nlm.nih.gov/19508979