Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Paola Londei"'
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/81a68957ba1e4142aa75437068523bdf
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/cc55278afbff42568206e240ceb71a80
Autor:
Paola Londei, Sébastien Ferreira-Cerca
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Making ribosomes is a major cellular process essential for the maintenance of functional ribosome homeostasis and to ensure appropriate gene expression. Strikingly, although ribosomes are universally conserved ribonucleoprotein complexes decoding the
Externí odkaz:
https://doaj.org/article/f9f47aa0180c461ab7c216af0f7e1cc7
Autor:
Giada Lo Gullo, Maria Luisa De Santis, Alessandro Paiardini, Serena Rosignoli, Alice Romagnoli, Anna La Teana, Paola Londei, Dario Benelli
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The translation factor IF6 is a protein of about 25 kDa shared by the Archaea and the Eukarya but absent in Bacteria. It acts as a ribosome anti-association factor that binds to the large subunit preventing the joining to the small subunit. It must b
Externí odkaz:
https://doaj.org/article/cbaf10abcc3c4408aea6f67802f53828
Autor:
Immacolata Maida, Paola Zanna, Stefania Guida, Anna Ferretta, Tiziana Cocco, Luigi Leonardo Palese, Paola Londei, Dario Benelli, Amalia Azzariti, Stefania Tommasi, Michele Guida, Giovanni Pellacani, Gabriella Guida
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Melanoma cells develop adaptive responses in order to cope with particular conditions of tumor microenvironment, characterized by stress conditions and deregulated proliferation. Recently, the interplay between the stress response
Externí odkaz:
https://doaj.org/article/dc132712efbe4cb783c347a39658ba21
Autor:
Giada Lo Gullo, Rosanna Mattossovich, Giuseppe Perugino, Anna La Teana, Paola Londei, Dario Benelli
Publikováno v:
Archaea, Vol 2019 (2019)
A system is described which permits the efficient synthesis of proteins in vitro at high temperature. It is based on the use of an unfractionated cell lysate (S30) from Sulfolobus solfataricus previously well characterized in our laboratory for trans
Externí odkaz:
https://doaj.org/article/4d9f443b0d74411aa993b5d0dd09c7a0
Publikováno v:
Archaea, Vol 2, Iss 3, Pp 151-158 (2008)
We have identified a novel archaeal protein that apparently plays two distinct roles in ribosome metabolism. It is a polypeptide of about 18 kDa (termed Rbp18) that binds free cytosolic C/D box sRNAs in vivo and in vitro and behaves as a structural r
Externí odkaz:
https://doaj.org/article/f9314a9db6d54a8f801bbc24e719e2bb
Autor:
Antimo Naspi, Vincenzo Panasiti, Franco Abbate, Vincenzo Roberti, Valeria Devirgiliis, Michela Curzio, Martina Borghi, Francesco Lozupone, Simone Carotti, Sergio Morini, Eugenio Gaudio, Stefano Calvieri, Paola Londei
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98641 (2014)
Insulin-like-factor-binding-protein 3 (IGFBP-3) is known to modulate the activity of insulin-like growth factors (IGFs) besides having a number of IGF-independent effects on cell growth and survival. IGFBP-3 has been reported to decrease significantl
Externí odkaz:
https://doaj.org/article/db9d71f0dfff4f599011d1c054e931e7
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32047 (2012)
A growing body of evidence indicates that protein factors controlling translation play an important role in tumorigenesis. The protein known as eIF6 is a ribosome anti-association factor that has been implicated in translational initiation and in rib
Externí odkaz:
https://doaj.org/article/c9d5f0e1d7db4d2b83854d560c44b21d
Autor:
Maria Zingariello, Dorina Polinari, Paola Londei, Vincenzo Panasiti, Antimo Naspi, Rana Rosa Alba, Laura Sancillo, Marianna Martella
Publikováno v:
Molecular Carcinogenesis. 56:681-693
In previous works, we have shown that insulin-like growth factor-binding protein-3 (IGFBP-3), a tissue and circulating protein able to bind to IGFs, decreases drastically in the blood serum of patients with diffuse metastatic melanoma. In agreement w