Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Paola Baiocco"'
Autor:
Lorenzo Barolo, Ylenia Gigante, Lorenza Mautone, Silvia Ghirga, Alessandro Soloperto, Alessandra Giorgi, Francesca Ghirga, Martina Pitea, Alessio Incocciati, Francesco Mura, Giancarlo Ruocco, Alberto Boffi, Paola Baiocco, Silvia Di Angelantonio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Tauopathies, including Alzheimer’s disease and Frontotemporal Dementia, are debilitating neurodegenerative disorders marked by cognitive decline. Despite extensive research, achieving effective treatments and significant symptom management
Externí odkaz:
https://doaj.org/article/d69b351b7e094759bfd10aa20ce9dd0f
Autor:
Francesca Romana Liberati, Sara Di Russo, Lorenzo Barolo, Giovanna Peruzzi, Maria Vittoria Farina, Sharon Spizzichino, Federica Di Fonzo, Deborah Quaglio, Luca Pisano, Bruno Botta, Alessandra Giorgi, Alberto Boffi, Francesca Cutruzzolà, Alessio Paone, Paola Baiocco
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 402 (2024)
Chronic lymphocytic leukemia (CLL) is a widespread type of leukemia that predominantly targets B lymphocytes, undermining the balance between cell proliferation and apoptosis. In healthy B cells, miR-15/16, a tandem of microRNAs, functions as a tumor
Externí odkaz:
https://doaj.org/article/c3cb26ae36b04029a7e08117175fdbb3
Autor:
Alessandro Soloperto, Deborah Quaglio, Paola Baiocco, Isabella Romeo, Mattia Mori, Matteo Ardini, Caterina Presutti, Ida Sannino, Silvia Ghirga, Antonia Iazzetti, Rodolfo Ippoliti, Giancarlo Ruocco, Bruno Botta, Francesca Ghirga, Silvia Di Angelantonio, Alberto Boffi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Numerous studies have shown a strong correlation between the number of neurofibrillary tangles of the tau protein and Alzheimer's disease progression, making the quantitative detection of tau very promising from a clinical point of view. How
Externí odkaz:
https://doaj.org/article/ea4bc56ead7f4f7b80769aef5c5bb896
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/fded2de4a2d1486eb951539dcff7f6f0
Autor:
Lorenzo Di Rienzo, Edoardo Milanetti, Claudia Testi, Linda Celeste Montemiglio, Paola Baiocco, Alberto Boffi, Giancarlo Ruocco
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 2678-2686 (2020)
Protein-protein interactions regulate almost all cellular functions and rely on a fine tune of surface amino acids properties involved on both molecular partners. The disruption of a molecular association can be caused even by a single residue mutati
Externí odkaz:
https://doaj.org/article/592c7c1f9b1d4423a9bee4991381d46f
Autor:
Linda Celeste Montemiglio, Claudia Testi, Pierpaolo Ceci, Elisabetta Falvo, Martina Pitea, Carmelinda Savino, Alessandro Arcovito, Giovanna Peruzzi, Paola Baiocco, Filippo Mancia, Alberto Boffi, Amédée des Georges, Beatrice Vallone
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The human transferrin receptor 1 (CD71) is a transmembrane protein responsible for iron uptake. Here the authors present the 3.9 Å resolution cryo-EM structure of the CD71 ectodomain-human ferritin (H-Ft) complex and find that H-Ft binds a CD71 regi
Externí odkaz:
https://doaj.org/article/61472d52cca641faa05071392f71cf5c
Autor:
Maria Rosito, Claudia Testi, Giacomo Parisi, Barbara Cortese, Paola Baiocco, Silvia Di Angelantonio
Publikováno v:
Antioxidants, Vol 9, Iss 8, p 700 (2020)
The maintenance of redox homeostasis in the brain is critical for the prevention of the development of neurodegenerative diseases. Drugs acting on brain redox balance can be promising for the treatment of neurodegeneration. For more than four decades
Externí odkaz:
https://doaj.org/article/bf4f3b60a13040a396f245b321d2cd3f
Autor:
Lorenzo Calisti, Matilde Cardoso Trabuco, Alberto Boffi, Claudia Testi, Linda Celeste Montemiglio, Amédée des Georges, Irene Benni, Andrea Ilari, Bartłomiej Taciak, Maciej Białasek, Tomasz Rygiel, Magdalena Król, Paola Baiocco, Alessandra Bonamore
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201859 (2018)
Ferritin H-homopolymers have been extensively used as nanocarriers for diverse applications in the targeted delivery of drugs and imaging agents, due to their unique ability to bind the transferrin receptor (CD71), highly overexpressed in most tumor
Externí odkaz:
https://doaj.org/article/dd405814a8d5434c9057374b1ebcf726
Autor:
Angela Capocefalo, Silvia Gentilini, Lorenzo Barolo, Paola Baiocco, Claudio Conti, Neda Ghofraniha
Publikováno v:
Photonics Research. 11:732
Highly accurate biosensors for few or single molecule detection play a central role in numerous key fields, such as healthcare and environmental monitoring. In the last decade, laser biosensors have been investigated as proofs of concept, and several
Autor:
Giovanna Peruzzi, Maria Elisa Crestoni, Chiara Massera, Bruno Botta, Davide Corinti, Natalia Pediconi, Deborah Quaglio, Cristina Del Plato, Alberto Boffi, Constantinos M. Athanassopoulos, Alessandro Arcovito, Paola Baiocco, Mattia Mori, Franco Ugozzoli, Francesca Ghirga
Publikováno v:
Bioconjugate Chemistry
Gene expression regulation by small interfering RNA (siRNA) holds promise in treating a wide range of diseases through selective gene silencing. However, successful clinical application of nucleic acid-based therapy requires novel delivery options. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de94336b281942850ab4ebc16c02726
http://hdl.handle.net/11573/1552342
http://hdl.handle.net/11573/1552342