Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Paola, Vitale"'
Autor:
Justinas J. Dainauskas, Paola Vitale, Sebastien Moreno, Hélène Marie, Michele Migliore, Ausra Saudargiene
Publikováno v:
Frontiers in Computational Neuroscience, Vol 17 (2023)
Alzheimer's disease (AD) is a progressive memory loss and cognitive dysfunction brain disorder brought on by the dysfunctional amyloid precursor protein (APP) processing and clearance of APP peptides. Increased APP levels lead to the production of AD
Externí odkaz:
https://doaj.org/article/3fbeb9410990434bb3863503c3256ca1
Autor:
Paola Vitale, Fabio Librizzi, Andrea C. Vaiana, Elisa Capuana, Maurizio Pezzoli, Ying Shi, Armando Romani, Michele Migliore, Rosanna Migliore
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The fundamental role of any neuron within a network is to transform complex spatiotemporal synaptic input patterns into individual output spikes. These spikes, in turn, act as inputs for other neurons in the network. Neurons must execute this functio
Externí odkaz:
https://doaj.org/article/02ad6e22254048d2aa16beb2b99abb6b
Publikováno v:
Molecules, Vol 29, Iss 6, p 1399 (2024)
An enhanced, sustainable, and efficient method for synthesizing tacrine, achieving a 98% yield, has been developed by replacing volatile organic compounds with more eco-friendly solvents such as deep eutectic solvent (DESs). The optimized protocol sc
Externí odkaz:
https://doaj.org/article/5a83505af50e4ce287bb42abe2d0a378
Autor:
Ivana Puliafito, Federico Chillari, Alessandro Russo, Ornella Cantale, Dorotea Sciacca, Luigi Castorina, Cristina Colarossi, Tindara Franchina, Maria Paola Vitale, Giuseppina Rosaria Rita Ricciardi, Vincenzo Adamo, Francesca Esposito, Dario Giuffrida
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundLung neuroendocrine neoplasms (NENs) are rare malignancies developed from bronchial mucosa. Because of its rarity and complex histopathology, there is limited data on the role of chemotherapy in this subset of tumors. Few studies regarding
Externí odkaz:
https://doaj.org/article/5b9b68db3bbc4daaaa657e8bcd742e49
Autor:
Dr. Luciana Cicco, Dr. Marianna Roggio, Marcos López‐Aguilar, Marina Ramos‐Martín, Prof. Dr. Filippo Maria Perna, Prof. Dr. Joaquín García‐Álvarez, Prof. Dr. Paola Vitale, Prof. Dr. Vito Capriati
Publikováno v:
ChemistryOpen, Vol 11, Iss 10, Pp n/a-n/a (2022)
Abstract An efficient, selective and sustainable protocol was developed for the CuCl2/TEMPO/TMEDA‐catalyzed aerobic oxidation of activated alcohols to the corresponding carbonyl compounds using water or the environmentally friendly low melting mixt
Externí odkaz:
https://doaj.org/article/a5b4d2ad0419425aafeea0d54180fcc6
Autor:
Andrea Nicola Paparella, Serena Perrone, Antonio Salomone, Francesco Messa, Luciana Cicco, Vito Capriati, Filippo Maria Perna, Paola Vitale
Publikováno v:
Catalysts, Vol 13, Iss 7, p 1035 (2023)
Polymeric materials are widely used in every human endeavor (bottles, clothes, containers, toys, tools, etc.) due to their unique properties of chemical and mechanical resistance. They are, however, almost non-biodegradable, and their chemical recycl
Externí odkaz:
https://doaj.org/article/9b123c713c084c28815565a41f673dfb
Autor:
Ivana Puliafito, Francesca Esposito, Angela Prestifilippo, Stefania Marchisotta, Dorotea Sciacca, Maria Paola Vitale, Dario Giuffrida
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Thyroid cancer (TC) is the most common endocrine malignancy. TC is classified as differentiated TC (DTC), which includes papillary and follicular subtypes and Hürthle cell variants, medullary TC (MTC), anaplastic TC (ATC), and poorly differentiated
Externí odkaz:
https://doaj.org/article/fd16bb55da064fc2a3630217ba7d2198
Autor:
Paola Vitale, Luciana Cicco, Ilaria Cellamare, Filippo M. Perna, Antonio Salomone, Vito Capriati
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1915-1923 (2020)
We report that phenacyl azides are key compounds for a regiodivergent synthesis of valuable, functionalized imidazole (32–98% yield) and pyrimidine derivatives (45–88% yield), with a broad substrate scope, when using deep eutectic solvents [choli
Externí odkaz:
https://doaj.org/article/03ae58a1b572458aa599f62129a43711
Autor:
Andrea Francesca Quivelli, Federico Vittorio Rossi, Chiara Alario, Francesco Sannicolò, Paola Vitale, Joaquín García-Álvarez, Filippo Maria Perna, Vito Capriati
Publikováno v:
Molecules, Vol 27, Iss 21, p 7594 (2022)
Dimethindene is a selective histamine H1 antagonist and is commercially available as a racemate. Upon analyzing the synthetic pathways currently available for the industrial preparation of dimethindene, we set up a sustainable approach for the synthe
Externí odkaz:
https://doaj.org/article/dd23def2d19e4a60ad8dedebc060825b
Autor:
Tiziana Boccuzzi, Luciana Cicco, Andrea Francesca Quivelli, Paola Vitale, Filippo Maria Perna, Konstantin Karaghiosoff, Vito Capriati
Publikováno v:
Molbank, Vol 2021, Iss 3, p M1267 (2021)
The lateral metalation-electrophilic trapping reaction of alkyl-substituted pyrazines has always been challenging and poorly regioselective, with the corresponding derivatives often being isolated in moderate yield. In this contribution, we first rep
Externí odkaz:
https://doaj.org/article/fc356e634b6d449b8d2c21721579aba3