Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Paola, Mura"'
Autor:
Francesca Maestrelli, Marzia Cirri, Natascia Mennini, Silvia Fiani, Beatrice Stoppacciaro, Paola Mura
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 633 (2024)
New oral tablets of nebivolol have been developed aiming to improve, by cyclodextrin (CD) complexation, its low solubility/dissolution properties—the main reason behind its poor/variable oral bioavailability. Phase-solubility studies, performed usi
Externí odkaz:
https://doaj.org/article/e417fe18ca5b48a58231e1c77318c1e1
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2217 (2023)
Propranolol (PPN) is widely used in children to treat various cardiovascular diseases. The availability of a suitable PPN solution should avoid recourse to extemporaneous preparations of unknown/limited stability, as commonly made in hospital pharmac
Externí odkaz:
https://doaj.org/article/9ea23bcfc2ec4c569a556ae37a3473c0
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2567 (2022)
Nanogels combine the properties of hydrogels and nanocarrier systems, resulting in very effective drug delivery systems, including for cutaneous applications. Cyclodextrins (CDs) have been utilised to enhance the nanogels’ loading ability towards p
Externí odkaz:
https://doaj.org/article/47bd99645ba643b6b4a30f32e63ad74d
Publikováno v:
Marine Drugs, Vol 20, Iss 5, p 335 (2022)
Chitosan (CS) is a linear polysaccharide obtained by the deacetylation of chitin, which, after cellulose, is the second biopolymer most abundant in nature, being the primary component of the exoskeleton of crustaceans and insects. Since joining the p
Externí odkaz:
https://doaj.org/article/5c887f89978f45aca8b4c25705d36421
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 284 (2022)
Flufenamic acid (FFA) is a non-steroidal anti-inflammatory drug characterised by a low solubility and problems of variable dissolution rate and bio-inequivalence. Different FFA batches, obtained by different suppliers, showed different powder charact
Externí odkaz:
https://doaj.org/article/ae158a51d9534d17b93364866b6420c3
Autor:
Marzia Cirri, Lavinia Maestrini, Francesca Maestrelli, Natascia Mennini, Paola Mura, Carla Ghelardini, Lorenzo Di Cesare Mannelli
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1910-1921 (2018)
The hydrochlorothiazide (HCT) low solubility and permeability give rise to limited and variable bioavailability; its low stability makes it difficult to develop stable aqueous liquid formulations; its low dose makes the achievement of a homogeneous d
Externí odkaz:
https://doaj.org/article/b3cef52e65084eed9725b8d03ede50e8
Autor:
Marzia Cirri, Natascia Mennini, Giulia Nerli, Jessica Rubia, Enrico Casalone, Fabrizio Melani, Francesca Maestrelli, Paola Mura
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1923 (2021)
Cefixime (CEF) is a cephalosporin included in the WHO Model List of Essential Medicines for Children. Liquid formulations are considered the best choice for pediatric use, due to their great ease of administration and dose-adaptability. Owing to its
Externí odkaz:
https://doaj.org/article/8ff4b916504049389c223a66506e05f6
Autor:
Paola Mura, Francesca Maestrelli, Marzia Cirri, Giulia Nerli, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Natascia Mennini
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 872 (2021)
This work was aimed at enhancing butamben (BTB) anesthetic efficacy by the “drug-in cyclodextrin (CD)-in deformable liposomes” strategy. In the study, phase-solubility studies with natural (α-, β-, γ-) and derivative (hydroxypropyl-α-and β-,
Externí odkaz:
https://doaj.org/article/a200ae2958a04c62b25aa54a31b77b1c
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 437 (2021)
The aim of this study was the optimization of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in terms of physicochemical and biopharmaceutical properties, to develop effective and stable aqueous liquid formulations of hydroch
Externí odkaz:
https://doaj.org/article/d11999919a564958b4c02bcecbce0e0d
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 503 (2020)
The aim of this work was to evaluate the effectiveness of mesoporous clays or silicas to develop fast-dissolving glyburide tablets based on a liquisolid approach. Selected clay (Neusilin®US2) and silica (Aeroperl®300) allowed preparation of innovat
Externí odkaz:
https://doaj.org/article/07370a1ab7074936ad74a6562b495391