Silencing of Ago-2 Interacting Protein SERBP1 Relieves KCC2 Repression by miR-92 in Neurons

Autor: Christian Barbato, Paola Frisone, Laura Braccini, Simona D’Aguanno, Luisa Pieroni, Maria Teresa Ciotti, Caterina Catalanotto, Carlo Cogoni, Francesca Ruberti

Publikováno v: Cells, Vol 11, Iss 6, p 1052 (2022)

RNA-binding proteins (RBPs) play important roles in modulating miRNA-mediated mRNA target repression. Argonaute2 (Ago2) is an essential component of the RNA-induced silencing complex (RISC) that plays a central role in silencing mechanisms via small

Externí odkaz: https://doaj.org/article/14956a062d714bbfa74ba609d5b200a0

The Promoter-Associated Noncoding RNA pncCCND1_B Assembles a Protein–RNA Complex to Regulate Cyclin D1 Transcription in Ewing Sarcoma

Autor: Paola Frisone, Claudio Sette, Neri Mercatelli, Ramona Palombo, Maria Paola Paronetto, Marco Fidaleo

Publikováno v: Cancer Research. 79:3570-3582

Most Ewing sarcomas are characterized by the in-frame chromosomal translocation t(11;22) generating the EWS–FLI1 oncogene. EWS–FLI1 protein interacts with the RNA helicase DHX9 and affects transcription and processing of genes involved in neoplas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1cc733c5a26f9b6d1aa00f4fe080a6
https://doi.org/10.1158/0008-5472.can-18-2403

The Promoter-Associated Noncoding RNA

Autor: Ramona, Palombo, Paola, Frisone, Marco, Fidaleo, Neri, Mercatelli, Claudio, Sette, Maria Paola, Paronetto

Publikováno v: Cancer research. 79(14)

Most Ewing sarcomas are characterized by the in-frame chromosomal translocation t(11;22) generating the EWS-FLI1 oncogene. EWS-FLI1 protein interacts with the RNA helicase DHX9 and affects transcription and processing of genes involved in neoplastic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28de5cc92bd7ca800682c5a5b1af950f
https://pubmed.ncbi.nlm.nih.gov/31072811

Selective inhibition of miR-92 in hippocampal neurons alters contextual fear memory

Autor: Carlo Cogoni, Martine Ammassari-Teule, Gisella Vetere, Christian Barbato, Silvia Pezzola, M.T. Ciotti, Massimiliano Aceti, Francesca Ruberti, Paola Frisone

Publikováno v: Hippocampus. 24:1458-1465

Post-transcriptional gene regulation mediated by micro- RNAs (miRNAs) is implicated in memory formation; however, the func- tion of miR-92 in this regulation is uncharacterized. The present study shows that training mice in contextual fear conditioni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce68d43cffac6076165e91e2fd2905c6
https://doi.org/10.1002/hipo.22326

A lentiviral sponge for miR-101 regulates RanBP9 expression and amyloid precursor protein metabolism in hippocampal neurons

Autor: Francesca Ruberti, Paola Frisone, Maria Teresa Ciotti, Silvia Pezzola, Christian Barbato, Cinzia Caggiano, Martina Antonelli

Publikováno v: Frontiers in Cellular Neuroscience, Vol 8 (2014)
Frontiers in Cellular Neuroscience
Frontiers in cellular neuroscience 8 (2014). doi:10.3389/fncel.2014.00037
info:cnr-pdr/source/autori:Barbato C.; Pezzola S.; Caggiano C.; Antonelli M.; Frisone P.; Ciotti M.T.; Ruberti F./titolo:A lentiviral sponge for miR-101 regulates RanBP9 expression and amyloid precursor protein metabolism in hippocampal neurons/doi:10.3389%2Ffncel.2014.00037/rivista:Frontiers in cellular neuroscience/anno:2014/pagina_da:/pagina_a:/intervallo_pagine:/volume:8

Neurodegeneration associated with amyloid beta (Abeta) peptide accumulation, synaptic loss, and memory impairment are pathophysiological features of Alzheimer's disease (AD). Numerous microRNAs regulate amyloid precursor protein (APP) expression and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d3dc89140ff186cb24bdc1b8818b3d
http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00037/full