Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Paola, Dama"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Our study employs pooled CRISPR screens, integrating 2D and 3D culture models, to identify miRNAs critical in Breast Cancer (BC) tumoursphere formation. These screens combine with RNA-seq experiments allowing identification of miRNA signatur
Externí odkaz:
https://doaj.org/article/d10079552a434611aad3e300b7500db5
Autor:
Ilaria Salvato, Luca Ricciardi, Jessica Dal Col, Annunziata Nigro, Giorgio Giurato, Domenico Memoli, Assunta Sellitto, Erwin Pavel Lamparelli, Maria Assunta Crescenzi, Monica Vitale, Alessandro Vatrella, Francesco Nucera, Paola Brun, Federico Caicci, Paola Dama, Thomas Stiff, Leandro Castellano, Sobia Idrees, Matt D. Johansen, Alen Faiz, Peter A. Wark, Philip M. Hansbro, Ian M. Adcock, Gaetano Caramori, Cristiana Stellato
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe RNA-binding protein AU-rich-element factor-1 (AUF-1) participates to posttranscriptional regulation of genes involved in inflammation and cellular senescence, two pathogenic mechanisms of chronic obstructive pulmonary disease (COPD).
Externí odkaz:
https://doaj.org/article/fe7d7b5136784084a80901875472e5fb
Autor:
Mohsen Sheykhhasan, Hamid Tanzadehpanah, Amirhossein Ahmadieh Yazdi, Hanie Mahaki, Reihaneh Seyedebrahimi, Mohammad Akbari, Hamed Manoochehri, Naser Kalhor, Paola Dama
Publikováno v:
Non-Coding RNA, Vol 9, Iss 1, p 1 (2022)
(1) Background: Mounting evidence supports the idea that one of the most critical agents in controlling gene expression could be long non-coding RNAs (lncRNAs). Upregulation of lncRNA is observed in the different processes related to pathologies, suc
Externí odkaz:
https://doaj.org/article/03a7ebe5badc4474b08d54ad24267b6d
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-7 (2019)
Abstract Immune checkpoint pathways active in Acute Myeloid Leukemia (AML) patients, especially during the course of remission induction chemotherapy, have not been well studied. Although dominant in mediating T cell dysfunction in cancer, it is now
Externí odkaz:
https://doaj.org/article/e8d2ccdbeeb942dda5ccfa646c2af6e6
Autor:
Daniela Maiello, Marianna Varone, Rosario Vicidomini, Valentina Belli, Marina De Rosa, Paola Dama, Maria Furia, Mimmo Turano
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1092 (2022)
Dyskerin is an evolutionarily conserved nucleolar protein implicated in a wide range of fundamental biological roles, including telomere maintenance and ribosome biogenesis. Germline mutations of DKC1, the human gene encoding dyskerin, cause the here
Externí odkaz:
https://doaj.org/article/474f4cc2d0794179ac569ae5c903c616
Autor:
Jairo A. Pinzon Cortes, Assam El-Osta, Giulia Fontemaggi, Nicholas Delihas, Katsuki Miyazaki, Ajay Goel, Mira Brazane, Clément Carré, Paola Dama, Salih Bayraktar, Leandro Castellano, Francisco J. Enguita, Tijana Mitic, Andrea Caporali, André P. Gerber, Nicola Amodio
Publikováno v:
Non-Coding RNA, Vol 8, Iss 1, p 3 (2022)
We are delighted to share with you our seventh Journal Club and highlight some of the most interesting papers published recently [...]
Externí odkaz:
https://doaj.org/article/0545555d57b34bb3a52e1be0e6bb7b51
Publikováno v:
Cancer Gene Therapy. 29:1866-1877
Breast cancer affects millions of women each year. Despite recent advances in targeted treatments breast cancer remains a significant threat to women’s health. In recent years the development of high-throughput sequencing technologies has advanced
Autor:
Mark Lythgoe, Benjamin Mullish, Adam Frampton, Paola Dama, Emily Pickford, Laura Tookman, Paula Cunnea, Christina Fotopoulou, Ian Jeffery, Gayle Fyvie, Alexander Stevenson, Jonathan Krell
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Aliyah R. Sohani, Charles Van Slambrouck, Girish Venkataraman, Cheolwon Suh, Sylvia Hartmann, Paola Dama, James Godfrey, Jooryung Huh, Reva C. Goldberg, Madhu P. Menon, Elaine S. Jaffe, Joo Y. Song, Carrie Fitzpatrick, Amy S. Duffield, Justin Kline, Kazuma Kiyotani, Sonali M. Smith
Publikováno v:
Modern Pathology. 33:834-845
Although the distinction of classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma using morphology and immunostains is straightforward in most instances, occasional cases pose diagnostic challenge. We sought to determine the
Publikováno v:
Cancer gene therapy. 29(8-9)
Acute lymphoblastic leukemia (ALL) is a cancer-specific lymphoid cell. Induction and consolidation chemotherapy alone or in combination with different therapeutic approaches remain the main treatment. Although complete or partial remission of the dis