Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Pao-Yun Cheng"'
Autor:
Shieh-Yang Huang, Ming-Ting Chung, Ching-Wen Kung, Shu-Ying Chen, Yi-Wen Chen, Tong Pan, Pao-Yun Cheng, Hsin-Hsueh Shen, Yen-Mei Lee
Publikováno v:
Journal of Obesity & Metabolic Syndrome, Vol 33, Iss 2, Pp 177-188 (2024)
Background : AMP-activated protein kinase (AMPK) is a key enzyme for cellular energy homeostasis and improves metabolic disorders. Brown and beige adipose tissues exert thermogenesis capacities to dissipate energy in the form of heat. Here, we invest
Externí odkaz:
https://doaj.org/article/d4b5a6e3db3d413f96a5229e58304255
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 717 (2024)
The heterogeneity of etiology may serve as a crucial factor in the challenges of treatment, including the low response rate and the delay in establishing therapeutic effect. In the present study, we examined whether social experience since early life
Externí odkaz:
https://doaj.org/article/1137d2df7569455c97ba1a7affbe9a0a
Publikováno v:
Chinese Journal of Physiology, Vol 65, Iss 2, Pp 80-86 (2022)
Obesity is a global health problem and a risk factor for cardiovascular diseases and cancers. Exercise is an effective intervention to combat obesity. Fibronectin type III domain containing protein 5 (FNDC5)/irisin, a myokine, can stimulate the brown
Externí odkaz:
https://doaj.org/article/0e4cf355d57646409a011502620a042b
Autor:
Je-Ming Hu, Chih-Hsueng Hsu, Yu-Chun Lin, Ching-Wen Kung, Shu-Ying Chen, Wen-Ting Lin, Pao-Yun Cheng, Hsin-Hsueh Shen, Yen-Mei Lee
Publikováno v:
International Journal of Hyperthermia, Vol 38, Iss 1, Pp 862-874 (2021)
Objective: Heat stroke (HS) elicits the systemic inflammatory responses that result in multiple organ dysfunction (MOD). Heat shock response and autophagy are activated during heat stress for removal of damaged organelles and proteins, emerging as a
Externí odkaz:
https://doaj.org/article/9ac4aaaf7ceb4066b8be6bcbb84fa04a
Autor:
Hsin-Hsueh Shen, Chien-Yi Yang, Ching-Wen Kung, Shu-Ying Chen, Hong-Min Wu, Pao-Yun Cheng, Kwok-Keung Lam, Yen-Mei Lee
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-12 (2019)
Abstract Background Loss of ovarian function, as in menopause or after ovariectomy (OVX), is closely associated with obesity and white adipose tissue (WAT) inflammation. Estrogen replacement protects against postmenopausal obesity but increases the r
Externí odkaz:
https://doaj.org/article/e01a016ffc074400932849e3def5051b
Autor:
Buh-Yuan Tai, Zhi-Hong Wen, Pao-Yun Cheng, Hsiang-Yu Yang, Chang-Yih Duh, Ping-Nan Chen, Chih-Hsueng Hsu
Publikováno v:
Marine Drugs, Vol 17, Iss 11, p 619 (2019)
Sepsis, an inflammatory response to infection provoked by lipopolysaccharide (LPS), is associated with high mortality, as well as ischemic stroke and new-onset atrial arrhythmia. Severe bacterial infections causing sepsis always result in profound ph
Externí odkaz:
https://doaj.org/article/3b029cfce4fc4acdaae8c872bc74ba49
Autor:
Yi-Li Wang, Hsin-Hsueh Shen, Pao-Yun Cheng, Yen-Ju Chu, Hwong-Ru Hwang, Kwok-Keung Lam, Yen-Mei Lee
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155583 (2016)
Sepsis is a systemic inflammatory disorder, accompanied with elevated oxidative stress, leading to multiple organ dysfunction syndrome (MODS), and disseminated intravascular coagulation. 17-Dimethylaminoethylamino- 17-demethoxygeldanamycin (17-DMAG),
Externí odkaz:
https://doaj.org/article/6251ab0dad5b4997a5a3cd7881f4a605
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 3, Pp 239-247 (2008)
Naltrexone, an opioid receptor antagonist, has been claimed to have anti-inflammatory and immunomodulatory effects both in vitro and in vivo. Thus, the aim of this study was to evaluate the effects of naltrexone on acute hepatitis induced by intraper
Externí odkaz:
https://doaj.org/article/b3d35259d39c4ab6a2536bb16a680a20
Autor:
Hwong-Ru Hwang, Buh-Yuan Tai, Pao-Yun Cheng, Ping-Nan Chen, Ping-Jyun Sung, Zhi-Hong Wen, Chih-Hsueng Hsu
Publikováno v:
Marine Drugs, Vol 15, Iss 2, p 25 (2017)
Severe bacterial infections caused by sepsis always result in profound physiological changes, including fever, hypotension, arrhythmia, necrosis of tissue, systemic multi-organ dysfunction, and finally death. The lipopolysaccharide (LPS) provokes an
Externí odkaz:
https://doaj.org/article/64868c4070614db1b6c12fde65895faf
Autor:
Yung-Chieh Tsai, Yen-Mei Lee, Kwok-Keung Lam, Jui-Fen Lin, Jhi-Joung Wang, Mao-Hsiung Yen, Pao-Yun Cheng
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69320 (2013)
Neurodegenerative brain disorders such as Alzheimer's disease (AD) have been well investigated. However, significant methods for the treatment of the progression of AD are unavailable currently. Heat shock protein 70 (Hsp70) plays important roles in
Externí odkaz:
https://doaj.org/article/75f2aa3b277e477c8d5a77a14b27157d