Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pao Chiung Hong"'
Autor:
Her Shyong Shiah, Pao Chiung Hong, Jang Yang Chang, Wan Shu Lee, Shin-Hun Juang, Ching Jer Chang, Chia Chi Lung, Kai Ming Chou
Publikováno v:
Biochemical Pharmacology. 73:610-619
D-501036 [2,5-bis(5-hydroxymethyl-2-selenienyl)-3-hydroxymethyl-N-methylpyrrol], a novel selenophene derivative, is a highly potent cytotoxic agent with broad spectrum antitumor activity. The present study was undertaken to explore the mechanism(s) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a5f0a3824185029fd93c8234986e4e
https://doi.org/10.1016/j.bcp.2006.10.019
https://doi.org/10.1016/j.bcp.2006.10.019
Autor:
Shin-Hun Juang, Ching Wei Huang, Hsu Pi Chen, Kai Ming Chou, Ching Jer Chang, Chia Chi Lung, Kuo Chu Fu, Leeyuan Huang, Ching Chuan Kuo, Yu Chin Wang, Cheng Li Hsu, Thomas C.K. Chan, Tom S. Chen, Jang Chang Chang, Curtis L. Ashendel, Kuo Shun Hsu, Shyh Fong Chen, Her Shyong Shiah, Li Yu Chen, Pao Chiung Hong, Meng Ju Lin
Publikováno v:
Molecular Cancer Therapeutics. 6:193-202
D-501036 [2,5-bis(5-hydroxymethyl-2-selenienyl)-3-hydroxymethyl-N-methylpyrrole] is herein identified as a novel antineoplastic agent with a broad spectrum of antitumoral activity against several human cancer cells and an IC50 value in the nanomolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b2065e5f2ad590acfb4fa053b0f8a2
https://doi.org/10.1158/1535-7163.mct-06-0482
https://doi.org/10.1158/1535-7163.mct-06-0482
Autor:
Yuh-Sheng Wen, Hsiang-Ling Huang, Lee Tai Liu, Chia-Lin Jeff Wang, Shyh-Fong Chen, Pao-Chiung Hong
Publikováno v:
Tetrahedron: Asymmetry. 12:419-426
A convenient and practical method for the preparation of chiral 4-aryl-2-piperidinone from 3-arylglutaric anhydride and (S)-methylbenzylamine is described. Acylation or alkylation at the α-carbon of the chiral 4-aryl-2-piperidinone product afforded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48a0b9359954eb903d5c8ec7dba952d2
https://doi.org/10.1016/s0957-4166(01)00069-6
https://doi.org/10.1016/s0957-4166(01)00069-6
Publikováno v:
Tetrahedron. 52:6325-6338
The cage-annulated cyclohexa-1,3-diene 4a was synthesized form the Diels-Alder adduct of 5,5-dimethoxy-1,2,3,4-tetrachlorocyclopentadiene (DTCP) and 1,4-naphthoquinone by a [6 + 2]photocycloaddition. The cyclohexadiene substructure in 4a undergoes Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36e08601b9a5ec2be1fc3916ec8fe0af
https://doi.org/10.1016/0040-4020(96)00273-6
https://doi.org/10.1016/0040-4020(96)00273-6
ChemInform Abstract: Asymmetric Syntheses of trans-3,4-Disubstituted 2-Piperidinones and Piperidines
Autor:
Shyh-Fong Chen, Hsiang-Ling Huang, Yuh-Sheng Wen, Lee Tai Liu, Chia-Lin Jeff Wang, Pao-Chiung Hong
Publikováno v:
ChemInform. 32
A convenient and practical method for the preparation of chiral 4-aryl-2-piperidinone from 3-arylglutaric anhydride and (S)-methylbenzylamine is described. Acylation or alkylation at the α-carbon of the chiral 4-aryl-2-piperidinone product afforded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fb18c722a2b74d871d25e9968e94962
https://doi.org/10.1002/chin.200130143
https://doi.org/10.1002/chin.200130143
Autor:
Win-Yin Wei, Ping-Kuei Tsai, Yann-Yu Lu, Huei-Yu Yang, Chu-Bin Liao, Pao-Chiung Hong, Hung-Yi Hsu, Shih-Jan Chiang, Tzu-Yun Lai, Li Jung Chen
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(17)
A series of selenophene derivatives 3 were synthesized as potential CHK1 inhibitors. The effects of substitution on the 4'- or 5'-position of selenophene moiety and shifting the hydroxyl group position on C6- phenolic ring of oxindole were explored.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dee702f7bf9213eb2ba8c69d31581d
https://pubmed.ncbi.nlm.nih.gov/20674356
https://pubmed.ncbi.nlm.nih.gov/20674356
Publikováno v:
Synthetic Communications. 22:429-443
Ozonides derived from cycloalkenes reacted with 2.2 equivalents of methyl (triphenylphosphoranylidene)acetate or (triphenylphosphoranylidene)acetophenone to form trans, trans-α,β,χ-unsaturated dioates or diones, respectively. The trapping experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e9b44ca5fbba1fdab5be982abc632c8
https://doi.org/10.1080/00397919208055421
https://doi.org/10.1080/00397919208055421
Publikováno v:
Tetrahedron Letters. 32:6351-6354
s - and C 2 -hexacycloeicosatetraendiones 2 are synthesized by a nine-step reaction sequence in overall yields of 15 – 20% from 1 serving as a cis-9, 10-dihydronaphthalene equivalent and 1,2,3,4-tetrachloro-5,5-dimethoxycyclopentadiene as a cyclope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c2a3268b8fc9cf75f78af0f437366b6
https://doi.org/10.1016/0040-4039(91)80167-5
https://doi.org/10.1016/0040-4039(91)80167-5