Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Panteleimon Rompolas"'
Autor:
Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang, Harun N. Noristani, Dan Li, Jingwen Niu, Shannon Trombley, Jessica I. Goldshteyn, Chuxi Wang, Shuchao Wang, Jingyun Qiu, Katarzyna Pogoda, Kalpana Mandal, Megan Brewster, Panteleimon Rompolas, Ye He, Paul A. Janmey, Gareth M. Thomas, Shuxin Li, Yuanquan Song
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery.
Externí odkaz:
https://doaj.org/article/005c24fb0ae4423db9855a4fda43b7ac
Autor:
Elisia D. Tichy, David K. Sidibe, Christopher D. Greer, Nicholas M. Oyster, Panteleimon Rompolas, Nadia A. Rosenthal, Helen M. Blau, Foteini Mourkioti
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Background Pax7 is a transcription factor involved in the specification and maintenance of muscle stem cells (MuSCs). Upon injury, MuSCs leave their quiescent state, downregulate Pax7 and differentiate, contributing to skeletal muscle regene
Externí odkaz:
https://doaj.org/article/27ec8e7c1d7b4772a6981532d288802e
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 961-966 (2015)
Most tissues in our bodies undergo constant cellular turnover. This process requires a dynamic balance between cell production and elimination. Stem cells have been shown in many of these tissues to be the major source of new cells. However, despite
Externí odkaz:
https://doaj.org/article/a229c884da6b40c89d143bb582a994ec
Autor:
Maxwell Marshall, Lisa Ohman, Bakary Samasa, Tyler Papp, Parhiz Hamideh, Panteleimon Rompolas
Loss of vision due to corneal endothelial dysfunction affects millions worldwide and has limited treatment options. Here we present a proof of concept for a therapeutic approach that aims to enhance regeneration of the corneal endothelium by inducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40820b4a06304dd059c3bf7734e054e6
https://doi.org/10.1101/2022.12.15.520611
https://doi.org/10.1101/2022.12.15.520611
Autor:
Sixia Huang, Paola Kuri, Jonathan Zou, Adriana Blanco, Maxwell Marshall, Gabriella Rice, Stephen Prouty, Tzvete Dentchev, Miriam Doepner, Joel D. Boerckel, Brian C. Capell, Todd W. Ridky, Panteleimon Rompolas
The skin has a pronounced ability to adapt to physical changes in the environment by exhibiting plasticity at the cellular level. Transient mechanical deformations applied to the skin are accommodated without permanent changes to tissue structure. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714a05a374eb0d68225c1cf05f754f77
https://doi.org/10.1101/2022.09.29.510204
https://doi.org/10.1101/2022.09.29.510204
Autor:
Vivian Lee, Panteleimon Rompolas
Publikováno v:
Current opinion in geneticsdevelopment. 77
The discovery of slow-cycling cells at the corneal periphery three decades ago established the limbus as the putative corneal stem cell niche. Since then, studies have underscored the importance of the limbal stem cells in maintaining the health and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402f1b015efe6c5c2ed14c954cab23c5
https://pubmed.ncbi.nlm.nih.gov/36084496
https://pubmed.ncbi.nlm.nih.gov/36084496
Autor:
Gabriella Rice, Panteleimon Rompolas
Publikováno v:
Curr Opin Cell Biol
The mammalian skin is equipped with a highly dynamic stratified epithelium. The maintenance and regeneration of this epithelium is supported by basally located keratinocytes which display stem cell properties, including lifelong proliferative potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62029134db00acce629e53325128252
https://doi.org/10.1016/j.ceb.2020.09.004
https://doi.org/10.1016/j.ceb.2020.09.004
Autor:
Nuoying Ma, Delia Chen, Ji-Hyung Lee, Paola Kuri, Edward Blake Hernandez, Jacob Kocan, Hamd Mahmood, Elisia D. Tichy, Panteleimon Rompolas, Foteini Mourkioti
Publikováno v:
Science advances. 8(11)
Muscle stem cells (MuSCs) are essential for tissue homeostasis and regeneration, but the potential contribution of MuSC morphology to in vivo function remains unknown. Here, we demonstrate that quiescent MuSCs are morphologically heterogeneous and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2cd5b508ec16fd4f7ddba9d0d6478dd
https://pubmed.ncbi.nlm.nih.gov/35302846
https://pubmed.ncbi.nlm.nih.gov/35302846
Autor:
Megan Brewster, Shuxin Li, Tsz Y. Lo, Jessica I. Goldshteyn, Leann Miles, Katarzyna Pogoda, Paul A. Janmey, Dan Li, Jingyun Qiu, Panteleimon Rompolas, Koushik Mandal, Gareth M. Thomas, Qin Wang, Yuanquan Song, Shannon Trombley, Shuchao Wang, Ye He, Chuxi Wang, Feng Li, Jingwen Niu, Harun N. Noristani
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Atr is a serine/threonine kinase, known to sense single-stranded DNA breaks and activate the DNA damage checkpoint by phosphorylating Chek1, which inhibits Cdc25, causing cell cycle arrest. This pathway has not been implicated in neuroregeneration. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e023285b7caa9e596dddd550e52ec3d1
https://doi.org/10.1038/s41467-021-24131-7
https://doi.org/10.1038/s41467-021-24131-7
Autor:
Mijail D. Serruya, H. Isaac Chen, Harry C. Ledebur, D. Kacy Cullen, Suradip Das, Foteini Mourkioti, Wisberty J. Gordián-Vélez, Panteleimon Rompolas
Publikováno v:
NPJ Regenerative Medicine
npj Regenerative Medicine, Vol 5, Iss 1, Pp 1-19 (2020)
npj Regenerative Medicine, Vol 5, Iss 1, Pp 1-19 (2020)
Innervation plays a pivotal role as a driver of tissue and organ development as well as a means for their functional control and modulation. Therefore, innervation should be carefully considered throughout the process of biofabrication of engineered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa75a9a017c2b6e84beef314ad2bae1
https://doi.org/10.1038/s41536-020-0096-1
https://doi.org/10.1038/s41536-020-0096-1