Recapitulation of human pathophysiology and identification of forensic biomarkers in a translational model of chlorine inhalation injury.

Autor: Achanta S; Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States., Gentile MA; Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States., Albert CJ; Department of Biochemistry and Molecular Biology, Saint Louis University, St. Louis, Missouri, United States., Schulte KA; Department of Biochemistry and Molecular Biology, Saint Louis University, St. Louis, Missouri, United States., Pantazides BG; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States., Crow BS; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States., Quiñones-González J; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States., Perez JW; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States., Ford DA; Department of Biochemistry and Molecular Biology, Saint Louis University, St. Louis, Missouri, United States., Patel RP; Center for Free Radical Biology and Lung Injury and Repair Center, The University of Alabama at Birmingham, Birmingham, Alabama, United States., Blake TA; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States., Gunn MD; Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States., Jordt SE; Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina, United States.; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, United States.; Integrated Toxicology & Environmental Health Program, Duke University, Durham, North Carolina, United States.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2024 Apr 01; Vol. 326 (4), pp. L482-L495. Date of Electronic Publication: 2024 Feb 06.

Development of a clinical assay to measure chlorinated tyrosine in hair and tissue samples using a mouse chlorine inhalation exposure model.

Autor: Pantazides BG; Emergency Response Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA, 30341, USA., Crow BS; Emergency Response Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA, 30341, USA. jgz8@cdc.gov., Quiñones-González J; Emergency Response Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA, 30341, USA.; San Juan Laboratory, Office of Medical Products and Specialty Laboratory Operations, Office of Regulatory Science, Office of Regulatory Affairs, U.S. Food and Drug Administration, 466 Fernandez Juncos Ave., San Juan, PR, 00901, USA., Perez JW; Emergency Response Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA, 30341, USA., Harvilchuck JA; Battelle Memorial Institute, 505 King Avenue, Columbus, OH, 43201, USA., Wallery JJ; Battelle Memorial Institute, 505 King Avenue, Columbus, OH, 43201, USA., Hu TC; Chemical Medical Countermeasures, Division of CBRN Countermeasures, Biomedical Advanced Research and Development Authority (BARDA), 330 Independence Ave, SW, Washington, DC, 20201, USA., Thomas JD; Emergency Response Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA, 30341, USA., Johnson RC; Emergency Response Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA, 30341, USA., Blake TA; Emergency Response Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, Atlanta, GA, 30341, USA.

Publikováno v: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2021 Mar; Vol. 413 (6), pp. 1765-1776. Date of Electronic Publication: 2021 Jan 28.

Analytical methods based on liquid chromatography for the analysis of albumin adducts involved in retrospective biomonitoring of exposure to mustard agents.

Autor: Avigo, Lorenzo^1,2 (AUTHOR), Hallez, Florine¹ (AUTHOR), Combès, Audrey¹ (AUTHOR), Desoubries, Charlotte³ (AUTHOR), Albaret, Christine³ (AUTHOR), Bossée, Anne³ (AUTHOR), Pichon, Valérie^1,2 (AUTHOR) valerie.pichon@espci.fr

Publikováno v: Analytical & Bioanalytical Chemistry. Apr2024, Vol. 416 Issue 9, p2173-2188. 16p.

Evaluation of Multiple Blood Matrices for Assessment of Human Exposure to Nerve Agents.

Autor: Schulze ND; Oak Ridge Institute for Scientific Education, Oak Ridge, TN 37831, USA., Hamelin EI; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA eph3@cdc.gov., Winkeljohn WR; Battelle, Atlanta, GA 30329, USA., Shaner RL; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA., Basden BJ; Battelle, Atlanta, GA 30329, USA., deCastro BR; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA., Pantazides BG; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA., Thomas JD; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA., Johnson RC; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.

Publikováno v: Journal of analytical toxicology [J Anal Toxicol] 2016 Apr; Vol. 40 (3), pp. 229-35. Date of Electronic Publication: 2016 Feb 08.

Enhanced stability of blood matrices using a dried sample spot assay to measure human butyrylcholinesterase activity and nerve agent adducts.

Autor: Perez JW; †Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, Georgia 30341, United States., Pantazides BG; †Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, Georgia 30341, United States., Watson CM; ‡Oak Ridge Institute for Science and Education Fellowship at the Center for Disease Control and Prevention, Atlanta, Georgia 30341, United States., Thomas JD; †Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, Georgia 30341, United States., Blake TA; †Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, Georgia 30341, United States., Johnson RC; †Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, Georgia 30341, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2015 Jun 02; Vol. 87 (11), pp. 5723-9. Date of Electronic Publication: 2015 May 20.