Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Panos Soultanas"'
Autor:
Panos Soultanas, Laurent Janniere
Publikováno v:
Open Biology, Vol 13, Iss 8 (2023)
Metabolism and DNA replication are the two most fundamental biological functions in life. The catabolic branch of metabolism breaks down nutrients to produce energy and precursors used by the anabolic branch of metabolism to synthesize macromolecules
Externí odkaz:
https://doaj.org/article/784433e1856447509ac55438ad6e8957
Autor:
Jennifer C. Okoye, Alexandria Holland, Matthaios Pitoulias, Vasileios Paschalis, Artem Piddubnyi, Osman A. Dufailu, Thomas Borén, Neil J. Oldfield, Jafar Mahdavi, Panos Soultanas
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Campylobacter jejuni colonizes hosts by interacting with Blood Group Antigens (BgAgs) on the surface of gastrointestinal epithelia. Genetic variations in BgAg expression affects host susceptibility to C. jejuni. Here, we show that the essential major
Externí odkaz:
https://doaj.org/article/c84216198c4f45a196212118ed939b0b
Autor:
Steff Horemans, Matthaios Pitoulias, Alexandria Holland, Emilie Pateau, Christophe Lechaplais, Dariy Ekaterina, Alain Perret, Panos Soultanas, Laurent Janniere
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-25 (2022)
Abstract Background In all living organisms, DNA replication is exquisitely regulated in a wide range of growth conditions to achieve timely and accurate genome duplication prior to cell division. Failures in this regulation cause DNA damage with pot
Externí odkaz:
https://doaj.org/article/9e500e5661c84960b75158bc4e1ffd60
Autor:
Jennifer C. Okoye, Jeddidiah Bellamy-Carter, Neil J. Oldham, Neil J. Oldfield, Jafar Mahdavi, Panos Soultanas
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5355-5363 (2022)
Ferric chelates like ferric tyrosinate (TYPLEX) and the closely related ferric quinate (QPLEX) are structural mimics of bacterial siderophores. TYPLEX has been trialled as a feed additive in farming of commercial broilers, reducing Campylobacter load
Externí odkaz:
https://doaj.org/article/eda1545e797f40e4bb545821f72409a0
Publikováno v:
Life, Vol 13, Iss 4, p 965 (2023)
The glycolytic enzyme PykA has been reported to drive the metabolic control of replication through a mechanism involving PykA moonlighting functions on the essential DnaE polymerase, the DnaC helicase and regulatory determinants of PykA catalytic act
Externí odkaz:
https://doaj.org/article/5ad812f4f98c4f568b9f7bdbd5d1f6d5
Autor:
Vasileios Paschalis, Emmanuelle Le Chatelier, Matthew Green, François Képès, Panos Soultanas, Laurent Janniere
Publikováno v:
Open Biology, Vol 7, Iss 9 (2017)
During Bacillus subtilis replication two replicative polymerases function at the replisome to collectively carry out genome replication. In a reconstituted in vitro replication assay, PolC is the main polymerase while the lagging strand DnaE polymera
Externí odkaz:
https://doaj.org/article/c1a877db92c2456eaa3693b01b51205b
Autor:
Vasileios Paschalis, Emmanuelle Le Chatelier, Matthew Green, François Képès, Panos Soultanas, Laurent Janniere
Publikováno v:
Open Biology, Vol 7, Iss 11 (2017)
Externí odkaz:
https://doaj.org/article/cd8a439b24b74244824237e83fe4b779
Autor:
Erika van Eijk, Vasileios Paschalis, Matthew Green, Annemieke H. Friggen, Marilynn A. Larson, Keith Spriggs, Geoffrey S. Briggs, Panos Soultanas, Wiep Klaas Smits
Publikováno v:
Open Biology, Vol 6, Iss 12 (2016)
DNA replication is an essential and conserved process in all domains of life and may serve as a target for the development of new antimicrobials. However, such developments are hindered by subtle mechanistic differences and limited understanding of D
Externí odkaz:
https://doaj.org/article/248898495cf54a4cba9f9e62fe7039cc
Autor:
Jafar Mahdavi, Pierre-Joseph Royer, Hong S. Sjölinder, Sheyda Azimi, Tim Self, Jeroen Stoof, Lee M. Wheldon, Kristoffer Brännström, Raymond Wilson, Joanna Moreton, James W. B. Moir, Carina Sihlbom, Thomas Borén, Ann-Beth Jonsson, Panos Soultanas, Dlawer A. A. Ala'Aldeen
Publikováno v:
Open Biology, Vol 3, Iss 10 (2013)
Interactions between commensal pathogens and hosts are critical for disease development but the underlying mechanisms for switching between the commensal and virulent states are unknown. We show that the human pathogen Neisseria meningitidis, the lea
Externí odkaz:
https://doaj.org/article/0922dc73be34404db1e8d80e0eb1dffe
Autor:
Liu He, Rebecca Lever, Andrew Cubbon, Muhammad Tehseen, Tabitha Jenkins, Alice O Nottingham, Anya Horton, Hannah Betts, Martin Fisher, Samir M Hamdan, Panos Soultanas, Edward L Bolt
Publikováno v:
Nucleic Acids Research. 51:1740-1749
DNA strand breaks are repaired by DNA synthesis from an exposed DNA end paired with a homologous DNA template. DNA polymerase delta (Pol δ) catalyses DNA synthesis in multiple eukaryotic DNA break repair pathways but triggers genome instability unle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd33cf03a1543691511a3ee856e40cb4
https://doi.org/10.1093/nar/gkad032
https://doi.org/10.1093/nar/gkad032