Supplementary Figure 2 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells

Autor: Richard Jove, Leandros Skaltsounis, Prokopios Magiatis, Panos Polychronopoulos, Anna Scuto, Yan Wang, Jun Wu, Fan Yang, Yan Tian, Sangkil Nam, Lucy Liu

Supplementary Figure 2 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7964c7f2c9d1fc7a3563d93ab77ed05f
https://doi.org/10.1158/0008-5472.22395317.v1

7-Bromoindirubin-3′-oxime induces caspase-independent cell death

Autor: Jacint Boix, Karima Bettayeb, Frank Totzke, Alexios-Leandros Skaltsounis, Jan Mester, Xènia Garrofé-Ochoa, Laurent Meijer, Panos Polychronopoulos, Yoan Ferandin, Prokopios Magiatis, Judit Ribas, Marie Knockaert, Christoph Schächtele

Publikováno v: Repositorio Abierto de la UdL
Universitad de Lleida
Oncogene
Oncogene, Nature Publishing Group, 2006, 25 (47), pp.6304-18. ⟨10.1038/sj.onc.1209648⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Oncogene, 2006, 25 (47), pp.6304-18. ⟨10.1038/sj.onc.1209648⟩

Indirubin, an isomer of indigo, is a reported inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3) as well as an agonist of the aryl hydrocarbon receptor (AhR). Indirubin is the active ingredient of a traditional Chines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5905aba6a45aa9ccd7ee5d0dd9704b32
https://doi.org/10.1038/sj.onc.1209648

Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins

Autor: Marc Blondel, Stéphane Bach, Dalho Han, Cem Elbi, Scott R. Nagy, Laurent Meijer, Maryse Leost, Paul Greengard, Marie Knockaert, Gordon L. Hager, Prokopios Magiatis, Michael S. Denison, Xiaozhou P. Ryan, Martine Ffrench, Leandros Skaltsounis, Panos Polychronopoulos

Publikováno v: Oncogene
Oncogene, 2004, 23, pp.4400-4412
Oncogene, Nature Publishing Group, 2004, 23, pp.4400-4412

Indirubin, a bis-indole obtained from various natural sources, is responsible for the reported antileukemia activity of a Chinese Medicinal recipe, Danggui Longhui Wan. However, its molecular mechanism of action is still not well understood. In addit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47688cf55b35b712f298d680ea29566d
https://hal.science/hal-00020122