Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Panos G, Ziros"'
Autor:
Sheng Huang, Panos G. Ziros, Dionysios V. Chartoumpekis, Georgios Psarias, Leonidas Duntas, Xinhe Zuo, Xinyi Li, Zhiguo Ding, Gerasimos P. Sykiotis
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 868 (2024)
Hashimoto’s thyroiditis (HT) is not only the most frequent autoimmune thyroid disease (AITD), but it also has a significant impact on patients’ health-related quality of life (HRQoL), and it has been variably associated with differentiated thyroi
Externí odkaz:
https://doaj.org/article/c20fcdd1d69a40e791de563d978196b1
Autor:
Zhong Peng, Panos G. Ziros, Tomaz Martini, Xiao-Hui Liao, Ron Stoop, Samuel Refetoff, Urs Albrecht, Gerasimos P. Sykiotis, Stephan Kellenberger
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract The body temperature of mice is higher at night than during the day. We show here that global deletion of acid-sensing ion channel 1a (ASIC1a) results in lower body temperature during a part of the night. ASICs are pH sensors that modulate n
Externí odkaz:
https://doaj.org/article/1a56f049de1e49678db476469c0d0a2b
Autor:
Panos G. Ziros, Dionysios V. Chartoumpekis, Ilias Georgakopoulos-Soares, Georgios Psarias, Gerasimos P. Sykiotis
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102978- (2024)
Iodide plays a pivotal role in thyroid homeostasis due to its crucial involvement in thyroid hormone biosynthesis. Exposure to pharmacological doses of iodide elicits in the thyroid an autoregulatory response to preserve thyroid function, as well as
Externí odkaz:
https://doaj.org/article/53420cb2b166475185ff126026ef555b
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 1015 (2022)
Background: Dimethyl fumarate (DMF), a drug used for the treatment of multiple sclerosis (MS) and psoriasis, has been shown to activate the Keap1/Nrf2 antioxidant response. Nrf2 exerts pleiotropic roles in the thyroid gland; among others, single nucl
Externí odkaz:
https://doaj.org/article/678b74fdbadb42b7842be4a08111328d
Autor:
Cedric O. Renaud, Panos G. Ziros, Dionysios V. Chartoumpekis, Massimo Bongiovanni, Gerasimos P. Sykiotis
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
The Keap1/Nrf2 pathway is a key mediator of general redox and tissue-specific homeostasis. It also exerts a dual role in cancer, by preventing cell transformation of normal cells but promoting aggressiveness, and drug resistance of malignant ones. Al
Externí odkaz:
https://doaj.org/article/868e5804eeca46b2b28347b866639367
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1138 (2020)
Research on the antioxidant pathway comprising the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) and its cytoplasmic inhibitor Kelch-like ECH-associated protein 1 (Keap1) is ever increasing. As modulators of this pathway hav
Externí odkaz:
https://doaj.org/article/38846ee2d9724d68a0db489b31b379b6
Autor:
Christina Thanas, Panos G. Ziros, Dionysios V. Chartoumpekis, Cédric O. Renaud, Gerasimos P. Sykiotis
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1082 (2020)
The thyroid gland has a special relationship with oxidative stress. On the one hand, like all other tissues, it must defend itself against reactive oxygen species (ROS). On the other hand, unlike most other tissues, it must also produce reactive oxyg
Externí odkaz:
https://doaj.org/article/e1f88ed9dc7e45f9903f42f73222199b
Autor:
Dionysios V. Chartoumpekis, Panos G. Ziros, Ilias Georgakopoulos-Soares, Adam A. T. Smith, Ana Claudia Marques, Mark Ibberson, Peter A. Kopp, Ioannis Habeos, Ioannis P. Trougakos, Nicholas K. H. Khoo, Gerasimos P. Sykiotis
Publikováno v:
Antioxidants, Vol 9, Iss 9, p 884 (2020)
Background: Thyroid follicular cells have physiologically high levels of reactive oxygen species because oxidation of iodide is essential for the iodination of thyroglobulin (Tg) during thyroid hormone synthesis. Thyroid follicles (the functional uni
Externí odkaz:
https://doaj.org/article/0957870309ba435c83822ad18103be25
Publikováno v:
Free radical biologymedicine. 190
The signaling pathway centered on the transcription factor nuclear erythroid factor 2-like 2 (Nrf2) has emerged during the last 15 years as a target for the prevention and treatment of diseases broadly related with oxidative stress such as cancer, ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672853922f05df4f1389603184879832
https://pubmed.ncbi.nlm.nih.gov/35988853
https://pubmed.ncbi.nlm.nih.gov/35988853
Publikováno v:
Antioxidants, Vol 8, Iss 9, p 353 (2019)
Nrf2 is a master transcriptional regulator of antioxidant and cytoprotective pathways. Currently in its third decade, research on Nrf2 has expanded to encompass not only basic but also clinical studies. In the present bibliometric review, we employed
Externí odkaz:
https://doaj.org/article/645c194212ec4f8094c02f654239f829