Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Panos Fidias"'
Autor:
Panos Fidias
Publikováno v:
Journal of Thoracic Oncology. 12:S167-S169
Autor:
Frank C. Detterbeck, Hiran C. Fernando, John R. Handy, Scott Firestone, Panos Fidias, Candice Johnstone, Ross M. Bremner, Helen J. Ross, John D. Mitchell, Kenneth A. Kesler, Thomas K. Varghese, Harvey I. Pass, Michael Lanuti, Virginia R. Litle, Todd S. Crocenzi
Publikováno v:
The Annals of thoracic surgery. 107(2)
Publikováno v:
New England Journal of Medicine. 373:1458-1467
A 29-year-old man presented with diarrhea of 1 month's duration. He had received a diagnosis of thymoma 5 years earlier; diarrhea developed during treatment with an investigational drug and worsened despite discontinuation of the drug. Diagnostic pro
Publikováno v:
New England Journal of Medicine. 370:2132-2140
A 64-year-old man was admitted to the hospital with recurrent pleuritic chest pain. Imaging showed a loculated left pleural effusion and underlying consolidation in the left lower lobe. Treatment with antibiotics brought some improvement, but pain re
Autor:
Noah C. Choi, Douglas J. Mathisen, Tristen Chun, Thomas J. Lynch, Richard L. Kradin, Andrzej Niemierko, Alan J. Fischman, Marek Ancukiewicz, Panos Fidias
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging
Purpose We investigated the metabolic response of lung cancer to radiotherapy or chemoradiotherapy by 18F-FDG PET and its utility in guiding timely supplementary therapy. Methods Glucose metabolic rate (MRglc) was measured in primary lung cancers dur
Autor:
Rebecca S. Heist, Alice T. Shaw, Alona Muzikansky, Meghan Campo, Jennifer S. Temel, Jeffrey A. Engelman, David E. Gerber, Justin F. Gainor, Panos Fidias, Lecia V. Sequist
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 11(11)
Objectives The mechanisms of acquired resistance to the irreversible EGFR inhibitor afatinib are not well documented. We performed this prospective clinical trial to determine the prevalence of the mutation T790M in afatinib-resistant patients. Metho
Autor:
Dean M. Donahue, Jeffrey A. Engelman, Noah C. Choi, Michael Lanuti, Ashok Muniappan, Rebecca S. Heist, Anthony J. Iafrate, José Baselga, Alice T. Shaw, Jennifer S. Temel, Lecia V. Sequist, Colleen L. Channick, Panos Fidias, John C. Wain, Sarah B. Goldberg, Darrell R. Borger, Rachel P. Rosovsky, E. Bast, Cameron D. Wright, Mari Mino-Kenudson, Belinda A. Waltman, Justin F. Gainor, Swathi Tammireddy, Laura Morrissey, Thomas J. Lynch, Douglas J. Mathisen, Henning A. Gaissert, Leif W. Ellisen, Subba R. Digumarthy, Inga T. Lennes, Alona Muzikansky, Henning Willers, Dora Dias-Santagata
Publikováno v:
Annals of Oncology. 22:2616-2624
Background: Personalizing non-small-cell lung cancer (NSCLC) therapy toward oncogene addicted pathway inhibition is effective. Hence, the ability to determine a more comprehensive genotype for each case is becoming essential to optimal cancer care. M
Autor:
Joel W. Neal, Thomas J. Lynch, Rebecca S. Heist, J. Paul Marcoux, Mark S. Huberman, Lecia V. Sequist, Panos Fidias, Alona Muzikansky, Jennifer S. Temel
Publikováno v:
Journal of Thoracic Oncology. 5(11):1855-1858
Introduction: Therapeutic agents directed against the epidermal growth factor receptor (EGFR) signaling pathway have been effective in the treatment of non-small cell lung cancer (NSCLC). Cetuximab is a monoclonal antibody against the EGFR receptor w
Autor:
David C. Caldwell, Thomas J. Lynch, Marsha Jones, Jennifer S. Temel, Tatjana Kolevska, Michael S. Rabin, Lecia V. Sequist, Panos Fidias, Mark S. Huberman, Craig W. Englund, Gail L. Brown, James G. Keck, Martin J. Edelman, Lisa Meng, Ralph V. Boccia, Ostap Melnyk, Howard A. Burris, R. J. Belt, Glenn Mills
Publikováno v:
Journal of Thoracic Oncology. 4:1389-1396
Introduction We aimed to evaluate the safety and efficacy of canfosfamide in combination with carboplatin and paclitaxel as first-line therapy in patients with locally advanced or metastatic non-small cell lung cancer. Methods This was a phase 1-2a,
Autor:
Panos Fidias, Nathan A. Pennell, T Jesse Kwoh, Richard S. Geary, Geoffrey I. Shapiro, Anthony L. Boral, Joseph Paul Eder, Bruce E. Johnson, Thomas J. Lynch, Jeffrey G. Supko, Arthur T. Skarin
Publikováno v:
Journal of Thoracic Oncology. 4(9):1156-1162
Background A phase I trial was performed to evaluate the administration of carboplatin/paclitaxel in combination with ISIS-5132, a phosphorothioate antisense oligodeoxynucleotide inhibitor of c- raf -1 kinase expression, in patients with advanced non