Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Panobacumab"'
1
Assessment of panobacumab as adjunctive immunotherapy for the treatment of nosocomial Pseudomonas aeruginosa pneumonia
Autor: Hedvika Lazar, Antonio Perez, Jean-Luc Pagani, Jean Chastre, Michael Tamm, Emmanuelle Mercier, Qin Lu, Y-A Que, Pierre-François Laterre, Bruno François, Jean-Jacques Rouby, E. Mus, Philippe Eggimann, Jorge Garbino, Michel Wolff, J.-P. Revelly
Publikováno v: European Journal of Clinical Microbiology and Infectious Diseases, vol. 33, no. 10, pp. 1861-1867
The fully human anti-lipopolysaccharide (LPS) immunoglobulin M (IgM) monoclonal antibody panobacumab was developed as an adjunctive immunotherapy for the treatment of O11 serotype Pseudomonas aeruginosa infections. We evaluated the potential clinical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6475dc41d0fe0ebd53e50be42b6bf68
http://doc.rero.ch/record/324810/files/10096_2014_Article_2156.pdf
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2
Akademický článek
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3
Development of a 4-valent genotyping assay for direct identification of the most frequent Pseudomonas aeruginosa serotypes from respiratory specimens of pneumonia patients
Autor: Holger Koch, Marianne Wyss, Sandra Jampen, Hedvika Lazar, Michael P. Rudolf, Thomas Emrich, Verena Gafner
Publikováno v: Journal of Medical Microbiology. 63:508-517
Pseudomonas aeruginosa is a common cause of nosocomial infections and is associated with high rates of mortality. In order to facilitate rapid and sensitive identification of the most prevalent serotypes of P. aeruginosa, we have developed a 4-valent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0263ff1a65fde6d38da7f13341fc4690
https://doi.org/10.1099/jmm.0.066043-0
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4
Anti-Pseudomonas aeruginosa serotype O11 LPS immunoglobulin M monoclonal antibody panobacumab (KBPA101) confers protection in a murine model of acute lung infection
Autor: Bernhard Ryffel, O. Rutschi, L. Fauconnier, M. P. Rudolf, Thomas Secher, Agata Szade, S. C. Fas
Publikováno v: Journal of Antimicrobial Chemotherapy. 66:1100-1109
To investigate the in vivo efficacy in a murine pulmonary infection model of panobacumab (KBPA101), a human IgM monoclonal antibody directed against the O-polysaccharide moiety of Pseudomonas aeruginosa serotype O11, and to describe the anti-inflamma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a566c8c75b62ce28a8b0188d3fa52a08
https://doi.org/10.1093/jac/dkr038
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5
The anti-Pseudomonas aeruginosa antibody Panobacumab is efficacious on acute pneumonia in neutropenic mice and has additive effects with meropenem
Autor: Louis Fauconnier, Marieke Mathieu, Michael Rudolf, Oliver Rutschi, Thomas Secher, Bernhard Ryffel, Stefanie C. Fas
Publikováno v: PLoS ONE, Vol 8, Iss 9, p e73396 (2013)
PLoS One
PLoS ONE
Pseudomonas aeruginosa ( P. aeruginosa ) infections are associated with considerable morbidity and mortality in immunocompromised patients due to antibiotic resistance. Therefore, we investigated the efficacy of the anti- P. aeruginosa serotype O11 l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e4479550b59c251a0029a3698cb486
http://europepmc.org/articles/PMC3759427?pdf=render
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7
Akademický článek
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