Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Pannan Miao"'
Autor:
Ruining Li, Ya Dong, Shah Nawaz Khan, Muhammad Kashif Zaman, Junliang Zhou, Pannan Miao, Lifu Hu, Zhankui Sun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The selective cleavage of inert C(sp3)-C(sp3) bonds and their subsequent functionalization is an important goal in synthetic organic chemistry. Here, the authors developed consecutive C–C bond cleavage from stable trisubstituted acids via photocata
Externí odkaz:
https://doaj.org/article/72f5f8a437a24b28820c9eae0ab7b77e
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Due to the ionic nature of its mechanism, the Mannich reaction can only use non-enolizable aldehydes as substrates. Here, the authors expand the scope of the classical Mannich reaction to enolizable aldehydes by employing a radical process resulting
Externí odkaz:
https://doaj.org/article/85b17ab32aad4d6a8bd0bf6d8e2bdfaa
Publikováno v:
Green Chemistry. 23:1638-1641
Cascade reactions are green and powerful transformations for building multiple carbon–carbon bonds in one step. Through a relay olefination and radical addition process, we were able to develop the cascade Wittig/hydroalkylation reactions induced b
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Nature Communications
Nature Communications
Aliphatic amine, especially tertiary aliphatic amine, is one of the most popular functionalities found in pharmaceutical agents. The Mannich reaction is a classical and widely used transformation for the synthesis of β-amino-carbonyl products. Due t
Autor:
Pannan Miao, Jiahui Lv, Feng He, Jingde Wu, Ana Xu, Qiuqiong Zhang, Chenggong Yu, Xiangna Zhang, Ying Qu
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:1859-1868
Histone deacetylase inhibitors (HDACIs) are effective small molecules in the treatment of human cancers. In our continuing efforts to develop novel N -hydroxyterephthalamide-based HDACIs, herein we report the design and development of a new class of