Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pankaj Paliwal"'
Autor:
Pankaj Paliwal, Gaurav Kumar, Saumitra Sen Singh, Ranjana Patnaik, Surya Pratap Singh, Hareram Birla, Sumedha Mukherjee, Sairam Krishnamurthy
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 392:1293-1309
The ischemic cascade is initiated in the hypoperfused region of the brain that leads to neuronal cell death. Identification of multi-target inhibitor against prominent molecular mediators of ischemic cascade might be a suitable strategy to combat cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d700abcff899f23913b21997da5d5c48
https://doi.org/10.1007/s00210-019-01670-x
https://doi.org/10.1007/s00210-019-01670-x
Autor:
Pankaj Paliwal, H. S. Tripathi, Sairam Krishnamurthy, Surendra Singh, Shashikant C.U. Patne, Arepalli Sampath Kumar
Publikováno v:
Materials Science and Engineering: C. 92:424-434
Peptic ulcer is prevalent in about 4% of the world population and nearly 10% of people have been affected by peptic ulcer at some point in their life. Therefore, there is a need for newer efficient and safe anti-ulcer agents. In the present strategy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dccccb4e34e9b7dc235c706959ea7d3f
https://doi.org/10.1016/j.msec.2018.06.068
https://doi.org/10.1016/j.msec.2018.06.068
Autor:
Nishant Patnaik, Ranjana Patnaik, Sumedha Mukherjee, Sairam Krishnamurthy, Gaurav Kumar, Pankaj Paliwal
Publikováno v:
Xenobiotica. 49:339-345
1. The present study is designed to investigate the brain distribution and plasma pharmacokinetics profiles of chlorogenic acid (CGA) after intranasal administration in Charles-Foster rats to evaluate whether the CGA molecules are transported directl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837cd6eb929bc2526038bc87866de6e5
https://doi.org/10.1080/00498254.2018.1445882
https://doi.org/10.1080/00498254.2018.1445882
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 43:205-213
Cerebral ischemia affects hepatic enzymes and brain permeability extensively. Piracetam was investigated up to phase III of clinical trials and there is lack of data on brain penetration in cerebral ischemic condition. Thus, knowledge of the pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bfe78f25a538ba0360abf7fc7b26ec
https://doi.org/10.1007/s13318-017-0435-9
https://doi.org/10.1007/s13318-017-0435-9
Publikováno v:
Cellular and Molecular Neurobiology. 37:1373-1386
The present study was performed to investigate the effect of piracetam on neuroinflammation induced by lipopolysaccharide (LPS) and resulting changes in cognitive behavior. Neuroinflammation was induced by a single dose of LPS solution infused into e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef9469d31cd40a83aef305a2224ae78
https://doi.org/10.1007/s10571-017-0468-2
https://doi.org/10.1007/s10571-017-0468-2
Autor:
Khemraj Lahre, Pankaj Paliwal, Ashok Kumar, Gopichand Gutti, Sairam Krishnamurthy, Ankit Ganeshpurkar, Devendra Kumar, Sushil Kumar Singh
Publikováno v:
Bioorganic chemistry. 90
Cholinergic hypothesis of Alzheimer’s disease has been advocated as an essential tool in the last couple of decades for the drug development. Here in, we report de novo fragment growing strategy for the design of novel 3,5-diarylpyrazoles and hit o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d612f52199993e3ee87c17ba059cfa4c
https://pubmed.ncbi.nlm.nih.gov/31271946
https://pubmed.ncbi.nlm.nih.gov/31271946
Publikováno v:
Advancement in the Pathophysiology of Cerebral Stroke ISBN: 9789811314520
Mitochondria supply energy to cells by generating ATP; thus it can be considered as one of the essential organelles of the cell. For the efficient working of cells, a good quality of mitochondria is essential; thus the elimination of injured or nonfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cb29d9f47c85e99b8dc32594160e89f
https://doi.org/10.1007/978-981-13-1453-7_6
https://doi.org/10.1007/978-981-13-1453-7_6
Autor:
Ranjana Patnaik, Pankaj Paliwal, Gaurav Kumar, Amit Kumar Tripathi, Sairam Krishnamurthy, Sumedha Mukherjee
Publikováno v:
Advancement in the Pathophysiology of Cerebral Stroke ISBN: 9789811314520
Stroke is still a leading cause of death and physical disability among adults. For stroke patients, there is a need for improved and effective therapy. Tissue plasminogen activator is a single FDA-approved drug available for treatment with short wind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c410dd14e64381bd00a8812eb9d7c0a
https://doi.org/10.1007/978-981-13-1453-7_9
https://doi.org/10.1007/978-981-13-1453-7_9
Autor:
Pralay Maiti, Sairam Krishnamurthy, Arun Kumar Mahanta, Sudipta Senapati, Siva Hemalatha, Pankaj Paliwal
Publikováno v:
Molecular pharmaceutics. 16(1)
The novel chitosan nanohybrid hydrogel and scaffold have been developed with high mechanical strength and tailor the drug release ability for their applications in the biomedical arena. Nanohybrid hydrogels are prepared in dilute acetic acid medium u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dd2b01f48bf8fc59841107a1454b77
https://pubmed.ncbi.nlm.nih.gov/30444624
https://pubmed.ncbi.nlm.nih.gov/30444624
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