Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Pankaj K Bagul"'
Autor:
Ramu Adela, Susheel Kumar Nethi, Pankaj K Bagul, Ayan K Barui, Saidulu Mattapally, Madhusudan Kuncha, Chitta R Patra, P Naveen Chander Reddy, Sanjay K Banerjee
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125270 (2015)
BackgroundWe have previously reported that increased glucose levels were associated with higher serum nitric oxide (NO) levels in fructose-fed insulin resistant rats. However, the relationship between hyperglycemia and serum NO level was not clear. T
Externí odkaz:
https://doaj.org/article/88cfec80494a49b6941fa8b1e3fc4543
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
BackgroundInflammation remains a crucial factor for progression of cardiac diseases and cardiac hypertrophy remains an important cause of cardiac failure over all age groups. As a key regulator of inflammation, toll-like receptor 4 (TLR4) plays an im
Externí odkaz:
https://doaj.org/article/14c56447609c44fa9b729ad02feb37c3
Publikováno v:
Cells, Vol 7, Iss 12, p 235 (2018)
Background and Purpose: Mitochondrial dysfunction remains the crucial cause for many heart diseases including diabetic cardiomyopathy (DCM). Sirtuin-3 (SIRT-3) is a protein deacetylase localized in the mitochondria and regulates mitochondrial functio
Externí odkaz:
https://doaj.org/article/08658d98ea77489fba8c90b80b2ea94d
Publikováno v:
Life sciences. 253
Aims To unravel the underlying mechanism of hepatic inflammation during type 2 diabetes (T2DM), we established the diabetic rat model by feeding with high fructose diet for twenty weeks and studied the involvement of inflammasome in the liver of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8f6a5dbd546b8e39370160037893ac
https://pubmed.ncbi.nlm.nih.gov/32371063
https://pubmed.ncbi.nlm.nih.gov/32371063
Publikováno v:
Biochemical and Biophysical Research Communications. 468:221-227
Sirtuins are the protein deacetylases, which are linked to metabolic diseases and aging. There are seven sirtuins present in cell, whose regulation in diabetic heart is yet to be explored. Resveratrol is a well-known activator of SIRT-1, but its effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3193acceccefe97c42d5c817cc76b40a
https://doi.org/10.1016/j.bbrc.2015.10.126
https://doi.org/10.1016/j.bbrc.2015.10.126
Publikováno v:
Cells, Vol 7, Iss 12, p 235 (2018)
Cells
Volume 7
Issue 12
Cells
Volume 7
Issue 12
Background and Purpose: Mitochondrial dysfunction remains the crucial cause for many heart diseases including diabetic cardiomyopathy (DCM). Sirtuin-3 (SIRT-3) is a protein deacetylase localized in the mitochondria and regulates mitochondrial functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d13f6b9b764a66b0688b768fdb361630
https://www.mdpi.com/2073-4409/7/12/235
https://www.mdpi.com/2073-4409/7/12/235
Autor:
Lingaiah Nagarapu, Sanjay K. Benerjee, Hanmanth Reddy Vulupala, Yasodakrishna Sajja, Raviteja Bandla, Pankaj K. Bagul
Publikováno v:
Bioorganic chemistry. 77
A novel triazole derivatives(±)-2-(hydroxymethyl)-7,8-dihydro-1H-indeno[5,4-b]furan-6(2H)-one (12a–j) were designed and synthesized by the reaction between racemic azide and terminal acetylenes under click chemistry reaction conditions followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5729bf83c30d25610f6a085e66c6c7
https://pubmed.ncbi.nlm.nih.gov/29502027
https://pubmed.ncbi.nlm.nih.gov/29502027
Autor:
Pankaj K. Bagul, Sanjay K. Banerjee
Publikováno v:
Current Molecular Medicine. 15:312-330
The increasing prevalence, involvement of several signaling pathways, variable pathogenesis, progressive natural history and complications of type 2 diabetes emphasize an urgent need for a molecule with multiple actions. Resveratrol (3,5,4'-trihydrox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685b547946321d8f3ab1721c61035cc8
https://doi.org/10.2174/1566524015666150505155702
https://doi.org/10.2174/1566524015666150505155702
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology, Vol 8 (2017)
Background- Inflammation remains a crucial factor for progression of cardiac diseases and cardiac hypertrophy remains an important cause of cardiac failure over all age groups. As a key regulator of inflammation, toll like receptor 4 (TLR4) plays an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3ed09a50468f870718205ff7a14884
http://europepmc.org/articles/PMC5479928
http://europepmc.org/articles/PMC5479928
Autor:
Sanjay K. Banerjee, Chandrakant Bagul, Mettu Ravinder, Vaidya Jayathirtha Rao, Keerthi Ravikanti, Jagadeesh Babu Nanubolu, Kolupula Srinivas, Pankaj K. Bagul, Thatikonda Narendar Reddy
Publikováno v:
European Journal of Medicinal Chemistry. 71:53-66
Baylis-Hillman chemistry derived four series of new epalrestat analogues were synthesized. Three structural changes are introduced in these 39 new epalrestat analogues synthesized. All compounds were evaluated for their in vitro aldose reductase inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878d812d3f4bb82a6e9da15af0c0868c
https://doi.org/10.1016/j.ejmech.2013.10.043
https://doi.org/10.1016/j.ejmech.2013.10.043