Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Pankaj D. Mehta"'
Autor:
Shan Liu, Shinae Park, Grant Allington, Frances Prelli, Yanjie Sun, Mitchell Martá-Ariza, Henrieta Scholtzova, Goutam Biswas, Bernard Brown, Philip B. Verghese, Pankaj D. Mehta, Yong-Uk Kwon, Thomas Wisniewski
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Inheritance of the apolipoprotein E4 (apoE4) genotype has been identified as the major genetic risk factor for late onset Alzheimer’s disease (AD). Studies have shown that apoE, apoE4 in particular, binds to amyloid-β (Aβ) peptides at re
Externí odkaz:
https://doaj.org/article/c20bbec876ff40f9b955ba8a66acaacb
Autor:
Hamid R Sohrabi, Kristyn A Bates, Michael eWeinborn, Romola S Bucks, Stephanie R Rainey-Smith, Mark A Rodrigues, Sabine M Bird, Belinda M Brown, John eBeilby, Matthew eHoward, Arthur eCriddle, Megan eWraith, Kevin eTaddei, Georgia eMartins, Athena ePaton, Tejal eShah, Satvinder S Dhaliwal, Pankaj D Mehta, Jonathan K Foster, Ian J Martins, Nicola T Lautenschlager, Francis eMastaglia, Simon M Laws, Ralph N Martins
Publikováno v:
Frontiers in Aging Neuroscience, Vol 7 (2015)
Cognitive decline and dementia due to Alzheimer’s disease have been associated with genetic, lifestyle, and environmental factors. A number of potentially modifiable risk factors should be taken into account when preventive or ameliorative interven
Externí odkaz:
https://doaj.org/article/96ba035a4f1e406a969e581541d55131
Biochemical Markers for Alzheimer Disease as Reflection of the Neuropathology in Cerebrospinal Fluid
Publikováno v:
Alzheimer Disease ISBN: 9781003067665
Alzheimer Disease
Alzheimer Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::969e409388e434992ebcb880af796426
https://doi.org/10.1201/9781003067665-18
https://doi.org/10.1201/9781003067665-18
Autor:
Anilkumar Pillai, Davide Bruno, Antero S Sarreal, Raymundo T Hernando, Leslie A Saint-Louis, Jay Nierenberg, Stephen D Ginsberg, Nunzio Pomara, Pankaj D Mehta, Henrik Zetterberg, Kaj Blennow, Peter F Buckley
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39358 (2012)
Brain derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of depression as well as neuropsychiatric and neurodegenerative disorders. Recent studies show a role of BDNF in energy metabolism and body weight regulation. We exam
Externí odkaz:
https://doaj.org/article/f6baac12d9134dd79489faff0bf9f1dd
Autor:
Lewis H. Kuller, James T. Becker, Russell P. Tracy, Chelsea M. Stillman, Pankaj D. Mehta, Oscar L. Lopez, Kirk I. Erickson
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Higher levels of physical activity (PA) reduce the risk of cognitive impairment, but the underlying mechanisms are unclear. Using longitudinal data from the Cardiovascular Health Study, we examined whether PA predicted plasma Aβ levels and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb3e322fa06ffa9e9e9a66fc46fdef0
https://doi.org/10.1002/acn3.397
https://doi.org/10.1002/acn3.397
Autor:
Pankaj D. Mehta
Publikováno v:
Down Syndrome and Alzheimer’s Disease ISBN: 9781315376875
Down Syndrome and Alzheimer’s Disease
Down Syndrome and Alzheimer’s Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0514850abf76d62910437139805459cd
https://doi.org/10.1201/9781315376875-4
https://doi.org/10.1201/9781315376875-4
Autor:
Lisa Mosconi, Lidia Glodzik, Elizabeth Pirraglia, Kenneth Rich, Susan De Santi, Yi Li, Hui Yu Wang, Wai Hon Tsui, Kaj Blennow, Pankaj D. Mehta, Henrik Zetterberg, Mony J. de Leon, Raymond Zinkowski
Publikováno v:
Neurobiology of Aging. 32:2131-2141
Little is known whether cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) can predict both memory decline and associated longitudinal medial temporal lobe (MTL) gray matter (GM) reductions in cognitively healthy individuals. Fifty-seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e4f49ae2fb6068dd6d8a8776fd06f6
https://doi.org/10.1016/j.neurobiolaging.2009.12.026
https://doi.org/10.1016/j.neurobiolaging.2009.12.026
Autor:
Pankaj D. Mehta, Ramin V. Parsey, Yaakov Stern, Gregory H. Pelton, Richard Mayeux, Davangere P. Devanand, Nicole Schupf
Publikováno v:
Neurology. 77:125-131
Objective: To evaluate the relations between PET Pittsburgh compound B (PiB-PET) binding (amyloid imaging) and plasma Aβ in patients with mild cognitive impairment (MCI) and similarly aged controls. Methods: In 20 patients with MCI and 19 cognitivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21e75cf0638975c91b13fdeeff219e0
https://doi.org/10.1212/wnl.0b013e318224afb7
https://doi.org/10.1212/wnl.0b013e318224afb7
Autor:
Frank Martiniuk, Henrik Zetterberg, Pankaj D. Mehta, Kaj Blennow, Nunzio Pomara, Davide Bruno, John J. Sidtis, Jay Nierenberg
Publikováno v:
Neurochemical Research. 36:1124-1128
A variable poly-T polymorphism in the TOMM40 gene, which is in linkage disequilibrium with APOE, was recently implicated with increased risk and earlier onset age for late-onset Alzheimer's disease in APOE ε3 carriers. To elucidate potential neurobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3fe47f96812175e1216c6d87ea31b5
https://doi.org/10.1007/s11064-011-0459-5
https://doi.org/10.1007/s11064-011-0459-5
Autor:
Domenico Praticò, Raymond Zinkowski, Pauline McHugh, Mony J. de Leon, Kenneth Rich, Elizabeth Pirraglia, Schantel Williams, Lidia Glodzik, Elizabeth Javier, Pankaj D. Mehta, Kaj Blennow, Lisa Mosconi, Rachel Mistur, Susan De Santi
Publikováno v:
Biological Psychiatry. 68:913-921
Epidemiology and imaging studies showed that cognitively normal (NL) individuals with a maternal history (MH) of late-onset Alzheimer's disease (LOAD) might be at increased risk for Alzheimer's disease (AD) compared with NL with a paternal history (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2fad12302c785117a90b8db43fe57f
https://doi.org/10.1016/j.biopsych.2010.07.011
https://doi.org/10.1016/j.biopsych.2010.07.011