Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Pankaj Chibber"'
Autor:
Kamalpreet Kaur Sandha, Chittaranjan Behera, Pankaj Chibber, Rajesh Kumar, Amit Kumar, Dilip M. Mondhe, Gurdarshan Singh, Prem N. Gupta
Publikováno v:
Molecular Pharmaceutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ce99e2400bf051326e62dbc301d6d55
https://doi.org/10.1021/acs.molpharmaceut.2c01081
https://doi.org/10.1021/acs.molpharmaceut.2c01081
Publikováno v:
Cytokine. 158:155978
Natural compounds and their synthesized analogues continue to be valuable sources in the discovery and development of novel anti-inflammatory agents. AL-04 is a thiol analogue derived from a natural sesquiterpene alantolactone, that demonstrated pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52f3ec7f3740e2e2fb67bfa90f1e05c
https://doi.org/10.1016/j.cyto.2022.155978
https://doi.org/10.1016/j.cyto.2022.155978
Autor:
Amit Kumar, Surjeet Singh, Pankaj Chibber, Gurdarshan Singh, Narinder kumar, Nitika Kapoor, Ram A. Vishwakarma, Tanveer Ahmad Malik, Sumit G. Gandhi, Praveen Kolimi, Amarinder Singh, Sheikh Tasduq Abdullah
Publikováno v:
International Immunopharmacology. 69:34-49
Rohitukine (referred to as RHK) is a bioactive chromone alkaloid isolated from the leaves of plant Dysoxylum binectariferum, which has been reported to possess diverse pharmacological properties for the treatment of inflammatory bowel disease (IBD),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7cde28d355a811c77d14fcd6d13636
https://doi.org/10.1016/j.intimp.2019.01.015
https://doi.org/10.1016/j.intimp.2019.01.015
Autor:
Anupam Bishayee, Chetan Kumar, Gourav Chandan, Reena V. Saini, Naresh Kumar Satti, Pankaj Chibber, Gurdarshan Singh, Adesh K. Saini, Ashwani Kumar, Henok Gulilat
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 89
Background Datura stramonium L. is widely used across the world for its therapeutic potential to treat inflammatory disorders. The current work was designed to isolate and identify steroidal lactones from D. stramonium leaves and evaluate their anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e388a6779f3d820148d27ccc9d93e3a8
https://pubmed.ncbi.nlm.nih.gov/34252723
https://pubmed.ncbi.nlm.nih.gov/34252723
Autor:
Irfan Ahmed, Syed Assim Haq, Anil Kumar, Pankaj Chibber, Gurdarshan Singh, Surjeet Singh, Amarinder Singh, Chetan Kumar, Ram A. Vishwakarma
Publikováno v:
International immunopharmacology. 83
Despite various advances in the arena of the current system of medicine, there are numerous side effects associated with the therapeutics which essentially demand research on the development of safer therapeutics. One way is to explore the bioactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bad6649fd294ace9111f61835febd23
https://pubmed.ncbi.nlm.nih.gov/32251963
https://pubmed.ncbi.nlm.nih.gov/32251963
Autor:
Divya Gupta, Priya Wazir, Anil Kumar, Sheikh Tasduq Abdullah, Surjeet Singh, Chetan Kumar, Pankaj Chibber, Gurdarshan Singh, Syed Assim Haq
Publikováno v:
Cytokine. 148:155688
Arthritis, a primary autoimmune disorder having a global incidence of 2.03% person/year, is presently being treated by many commercially available drugs that treat symptomatically or improve the disease's clinical state; however, all the therapies po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfebd3c2fb2de522f604c3e0fd4ebc3
https://doi.org/10.1016/j.cyto.2021.155688
https://doi.org/10.1016/j.cyto.2021.155688
Autor:
Sanjeev Kumar Digra, Abubakar Wani, Ajay Kumar, Pankaj Chibber, Surjeet Singh, Gurdarshan Singh, Mehak Gupta, Ram A. Vishwakarma, Aitizaz Ul Ahsan, Sandip B. Bharate, Mehboob Ali, Manish Datt
Publikováno v:
Toxicology and Applied Pharmacology. 423:115582
NLRP3 inflammasome is involved in several chronic inflammatory diseases. The inflammatory effect of the NLRP3 inflammasome is executed through IL-1β and IL-18. Therefore, IL-1β is one of the primary targets in chronic inflammatory conditions. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf62c9f95149796f23d86839bbf30428
https://doi.org/10.1016/j.taap.2021.115582
https://doi.org/10.1016/j.taap.2021.115582
Publikováno v:
European Journal of Pharmacology
The emergence of the global pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has put a challenge to identify or derive the therapeutics for its prevention and treatment. Despite the unprecedented advances in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f16c569dfc4e0df7191c51515fd89f
https://doi.org/10.1016/j.ejphar.2020.173372
https://doi.org/10.1016/j.ejphar.2020.173372
Autor:
Sameer Ahmad Mir, Thanusha Thatikonda, Santosh Kumar Guru, Gousia Chashoo, Utpal Nandi, Anjna Sharma, Dilip M. Mondhe, Parvinder Pal Singh, Hariprasad Aruri, Sreedhar Madishetti, Sonali S. Bharate, Promod Kumar Sahu, Sameer U. Khan, Vikas Kumar, Shashi Bhushan, Girish Badrinath Mahajan, Umed Singh, Amarinder Singh, Fayaz Malik, Mubashir J. Mintoo, Pankaj Chibber, Gurdarshan Singh, Ram A. Vishwakarma, Amit Nargotra, Serge Mignani, Priya Mahajan
Publikováno v:
Journal of medicinal chemistry. 60(23)
In the present study, a novel series of 3-pyrimidinylazaindoles were designed and synthesized using a bioinformatics strategy as cyclin-dependent kinases CDK2 and CDK9 inhibitors, which play critical roles in the cell cycle control and regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8f31005b89a7e86fe47a7f3b7924b2
https://pubmed.ncbi.nlm.nih.gov/29144137
https://pubmed.ncbi.nlm.nih.gov/29144137