Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Pankaj, Tailor"'
Autor:
Roman J. Krawetz, Saleem Abubacker, Catherine Leonard, Anand O. Masson, Sophia Shah, Nadia Narendran, Pankaj Tailor, Suresh C. Regmi, Elodie Labit, Nicoletta Ninkovic, Jessica May Corpuz, Kenichi Ito, T. Michael Underhill, Paul T. Salo, Tannin A. Schmidt, Jeff A. Biernaskie
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-18 (2022)
Abstract The wound healing response is one of most primitive and conserved physiological responses in the animal kingdom, as restoring tissue integrity/homeostasis can be the difference between life and death. Wound healing in mammals is mediated by
Externí odkaz:
https://doaj.org/article/6cfd5dea43f0478bbcc1d17da0a3891f
Autor:
Priyatha Premnath, Britta Jorgenson, Ricarda Hess, Pankaj Tailor, Dante Louie, Jaymi Taiani, Steven Boyd, Roman Krawetz
Publikováno v:
BMC Musculoskeletal Disorders, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background p21(WAF1/CIP1/SDI1), a cyclin dependent kinase inhibitor has been shown to influence cell proliferation, differentiation and apoptosis; but more recently, p21 has been implicated in tissue repair. Studies on p21(−/−) knockout
Externí odkaz:
https://doaj.org/article/2bce679d2ba0490ba3a16acbc05357da
Autor:
Dae-Sun Kim, Himika Dastidar, Chunfen Zhang, Franz J. Zemp, Keith Lau, Matthias Ernst, Andrea Rakic, Saif Sikdar, Jahanara Rajwani, Victor Naumenko, Dale R. Balce, Ben W. Ewanchuk, Pankaj Tailor, Robin M. Yates, Craig Jenne, Chris Gafuik, Douglas J. Mahoney
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Oncolytic viruses (OV) and second mitochondrial activator of caspase (Smac)-mimetic compounds (SMC) synergistically kill cancer cells directly. Here, the authors show that SMC and OV therapies combination also synergize in vivo by promoting anticance
Externí odkaz:
https://doaj.org/article/f1edf28f5df34c7d87c29319c84877f7
Autor:
Euan R. O. Allan, Rhiannon I. Campden, Benjamin W. Ewanchuk, Pankaj Tailor, Dale R. Balce, Neil T. McKenna, Catherine J. Greene, Amy L. Warren, Thomas Reinheckel, Robin M. Yates
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background Hypomethylation of the cathepsin Z locus has been proposed as an epigenetic risk factor for multiple sclerosis (MS). Cathepsin Z is a unique lysosomal cysteine cathepsin expressed primarily by antigen presenting cells. While cathe
Externí odkaz:
https://doaj.org/article/3607ebe548f447d3961f94e616a73df4
Autor:
Karri L. Bertram, Nadia Narendran, Pankaj Tailor, Christina Jablonski, Catherine Leonard, Edward Irvine, Ricarda Hess, Anand O. Masson, Saleem Abubacker, Kristina Rinker, Jeff Biernaskie, Robin M. Yates, Paul Salo, Aru Narendran, Roman J. Krawetz
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 10 (2018)
Cartilage degeneration after injury affects a significant percentage of the population, including those that will go on to develop osteoarthritis (OA). Like humans, most mammals, including mice, are incapable of regenerating injured cartilage. Intere
Externí odkaz:
https://doaj.org/article/8f689fa1ed9f41bab97e7922b4d6a2d5
Autor:
Dae-Sun Kim, Himika Dastidar, Chunfen Zhang, Franz J. Zemp, Keith Lau, Matthias Ernst, Andrea Rakic, Saif Sikdar, Jahanara Rajwani, Victor Naumenko, Dale R. Balce, Ben W. Ewanchuk, Pankaj Tailor, Robin M. Yates, Craig Jenne, Chris Gafuik, Douglas J. Mahoney
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The originally published version of this article contained an error in the spelling of the author Pankaj Tailor, which was incorrectly given as Pankaj Taylor. This has now been corrected in both the PDF and HTML versions of the article.
Externí odkaz:
https://doaj.org/article/01f58fd455364410985bc25d2d498a40
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131661 (2015)
Articular cartilage has been the focus of multiple strategies to improve its regenerative/ repair capacity. The Murphy Roths Large (MRL/MpJ) "super-healer" mouse demonstrates an unusual enhanced regenerative capacity in many tissues and provides an o
Externí odkaz:
https://doaj.org/article/39bf43979a78482dbc2e9b1ac917354b
Autor:
Andrea Rakic, Jahanara Rajwani, Keith C.K. Lau, Franz J. Zemp, Robin M. Yates, Himika Dastidar, Dae-Sun Kim, Matthias Ernst, Chris Gafuik, Pankaj Tailor, Victor Naumenko, Chunfen Zhang, Saif Sikdar, Douglas J. Mahoney, Ben W. Ewanchuk, Dale R. Balce, Craig N. Jenne
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature Communications
Second mitochondrial activator of caspase (Smac)-mimetic compounds and oncolytic viruses were developed to kill cancer cells directly. However, Smac-mimetic compound and oncolytic virus therapies also modulate host immune responses in ways we hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d784dafa1365cc1387e4bc854680946
http://link.springer.com/article/10.1038/s41467-017-00324-x
http://link.springer.com/article/10.1038/s41467-017-00324-x
Autor:
Jung Hwan Kim, Margaret M. Kelly, Pankaj Tailor, Gary R. Martin, Laura J Eggen, Teresa Scheidl-Yee, John Podstawka, Kimiora Henare, Bryan G. Yipp, Frank R. Jirik, Marvin J. Fritzler, Carolina Salazar
Publikováno v:
Life Science Alliance
Transgenic expression of a mutant hSTING cDNA under the control of the Vav1 gene promoter leads to a vasculopathy similar to that of the interferonopathy, STING-associated vasculopathy of infancy.
STING-associated vasculopathy with onset in infa
STING-associated vasculopathy with onset in infa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc64ab05c9becbf47a80a1665eaa9d33
http://europepmc.org/articles/PMC6587127
http://europepmc.org/articles/PMC6587127
Publikováno v:
Journal of Leukocyte Biology. 100:17-26
Although endosomes, lysosomes, and phagosomes require a reductive environment for the optimal activity of disulfide reductases and other thiol-dependent enzymes, how these reductive environments are established and maintained remain unknown. Our goal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab656eeaba51a4891e4894380fa790a5
https://doi.org/10.1189/jlb.2hi0315-083r
https://doi.org/10.1189/jlb.2hi0315-083r