Fmp40 ampylase regulates cell survival upon oxidative stress by controlling Prx1 and Trx3 oxidation.

Autor: Masanta S; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., Wiesyk A; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., Panja C; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., Pilch S; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., Ciesla J; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., Sipko M; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., De A; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., Enkhbaatar T; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., Maslanka R; Institute of Biology, College of Natural Sciences, University of Rzeszow, Rzeszow, Poland., Skoneczna A; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland., Kucharczyk R; Institute of Biochemistry and Biophysics PAS, Warsaw, 02-106, Pawinskiego 5A, Poland. Electronic address: roza@ibb.waw.pl.

Publikováno v: Redox biology [Redox Biol] 2024 Jul; Vol. 73, pp. 103201. Date of Electronic Publication: 2024 May 21.

Analysis of MT-ATP8 gene variants reported in patients by modeling in silico and in yeast model organism.

Autor: Panja C; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Niedzwiecka K; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Baranowska E; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Poznanski J; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Kucharczyk R; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland. roza@ibb.waw.pl.

Publikováno v: Scientific reports [Sci Rep] 2023 Jun 20; Vol. 13 (1), pp. 9972. Date of Electronic Publication: 2023 Jun 20.

Probing the pathogenicity of patient-derived variants of MT-ATP6 in yeast.

Autor: Baranowska E; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02106 Warsaw, Poland., Niedzwiecka K; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02106 Warsaw, Poland., Panja C; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02106 Warsaw, Poland., Charles C; University of Bordeaux, Centre National de la Recherche Scientifique, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France., Dautant A; University of Bordeaux, Centre National de la Recherche Scientifique, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France., Poznanski J; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02106 Warsaw, Poland., di Rago JP; University of Bordeaux, Centre National de la Recherche Scientifique, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France., Tribouillard-Tanvier D; University of Bordeaux, Centre National de la Recherche Scientifique, Institut de Biochimie et Génétique Cellulaires, UMR 5095, F-33000 Bordeaux, France., Kucharczyk R; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02106 Warsaw, Poland.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2023 Apr 01; Vol. 16 (4). Date of Electronic Publication: 2023 Apr 21.

Creation of Yeast Models for Evaluating the Pathogenicity of Mutations in the Human Mitochondrial Gene MT-ATP6 and Discovering Therapeutic Molecules.

Autor: Tribouillard-Tanvier D; Univ. Bordeaux, CNRS, IBGC, UMR 5095, Bordeaux, France.; INSERM, Paris, France., Dautant A; Univ. Bordeaux, CNRS, IBGC, UMR 5095, Bordeaux, France., Godard F; Univ. Bordeaux, CNRS, IBGC, UMR 5095, Bordeaux, France., Charles C; Univ. Bordeaux, CNRS, IBGC, UMR 5095, Bordeaux, France., Panja C; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., di Rago JP; Univ. Bordeaux, CNRS, IBGC, UMR 5095, Bordeaux, France. jp.dirago@ibgc.cnrs.fr., Kucharczyk R; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland. roza@ibb.waw.pl.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2497, pp. 221-242.

Design, synthesis and SAR study of bridged tricyclic pyrimidinone carboxamides as HIV-1 integrase inhibitors.

Autor: Patel M; Departments of Discovery Chemistry and Molecular Technologies, 5 Research Parkway, Wallingford, CT 06492, USA; ViiV Healthcare, 36 East Industrial Parkway, Branford, CT 06405, USA. Electronic address: manoj.m.patel@viivhealthcare.com., Naidu BN; Departments of Discovery Chemistry and Molecular Technologies, 5 Research Parkway, Wallingford, CT 06492, USA; ViiV Healthcare, 36 East Industrial Parkway, Branford, CT 06405, USA., Dicker I; Virology, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA; ViiV Healthcare, 36 East Industrial Parkway, Branford, CT 06405, USA., Higley H; Virology, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Lin Z; Virology, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Terry B; Virology, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Protack T; Virology, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA., Krystal M; Virology, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA; ViiV Healthcare, 36 East Industrial Parkway, Branford, CT 06405, USA., Jenkins S; Departments of Discovery Chemistry and Molecular Technologies, 5 Research Parkway, Wallingford, CT 06492, USA; ViiV Healthcare, 36 East Industrial Parkway, Branford, CT 06405, USA., Parker D; Departments of Discovery Chemistry and Molecular Technologies, 5 Research Parkway, Wallingford, CT 06492, USA; ViiV Healthcare, 36 East Industrial Parkway, Branford, CT 06405, USA., Panja C; Biocon-Bristol-Myers Squibb Research Center, Plot 2 & 3, Bommasandra Industrial Estate - Phase-IV, Bommasandra-Jigani Link Road, Bengaluru, Karnataka 560099, India., Rampulla R; Department of Discovery Chemistry Synthesis, Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA., Mathur A; Department of Discovery Chemistry Synthesis, Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA., Meanwell NA; Departments of Discovery Chemistry and Molecular Technologies, 5 Research Parkway, Wallingford, CT 06492, USA., Walker MA; Departments of Discovery Chemistry and Molecular Technologies, 5 Research Parkway, Wallingford, CT 06492, USA; Assembly Biosciences, Inc. 331 Oyster Point Blvd, San Francisco, CA 94080, USA.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Jul 01; Vol. 28 (13), pp. 115541. Date of Electronic Publication: 2020 May 04.