Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pang-Bo Li"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-16 (2024)
Abstract The mitochondrial dynamic imbalance is an important cause of myocardial ischaemia/reperfusion (I/R) injury and dysfunction. Psmb8, as one of the immunoproteasome catalytic subunits, is a key regulator of protein homoeostasis, inflammation an
Externí odkaz:
https://doaj.org/article/c42f94fde93b42ac9f26e9046785c5cc
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102706- (2023)
Oxidative stress is considered a key factor contributing to the initiation and development of cardiac injury following ischaemia‒reperfusion (I/R). Arachidonate 5-lipoxygenase (ALOX5) is a rate-limiting enzyme for leukotriene biosynthesis. MK-886 i
Externí odkaz:
https://doaj.org/article/6823f761691f4cf8bfaba95fbd25f0f8
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Septic cardiomyopathy is the main complication and cause of death of severe sepsis with limited therapeutic strategy. However, the molecular mechanism of sepsis-induced cardiac injury remains unclear. The present study was designed to investigate dif
Externí odkaz:
https://doaj.org/article/b0d4fe948d704af8ad5fce7a3a29d022
Publikováno v:
Nutrients, Vol 15, Iss 4, p 1049 (2023)
Cardiac ischaemia/reperfusion (I/R) injury causes cardiomyocyte apoptosis and mitochondrial dysfunction. Ursolic acid (UA), as a pentacyclic triterpenoid carboxylic acid, exerts several bioactivities in animal models of different diseases, but the pr
Externí odkaz:
https://doaj.org/article/9bfa3c9f59e84b74a3d1c5a60a6938c0
Publikováno v:
Journal of Hypertension. 40:765-775
Angiotensin (Ang) II and elevated blood pressure are considered to be the main risk factors for atrial fibrillation. However, the proteome profiles and key mediators/signaling pathways involved in the development of Ang II-induced atrial fibrillation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0ed356fccfb600622093092cd53d9b
https://doi.org/10.1097/hjh.0000000000003075
https://doi.org/10.1097/hjh.0000000000003075
Autor:
Yunlong Xia, Pang-Bo Li, Hua-Jun Cao, Jie Yang, Chen Chen, Fei Teng, Shu-Bin Guo, Ying Liu, Xiao Yan, Yun-Long Zhang, Xiao Han, Hui-Hua Li
Publikováno v:
Hypertension. 76:381-392
Atrial fibrillation (AF) is frequently associated with increased inflammatory response characterized by infiltration of monocytes/macrophages. The chemokine receptor CXCR-2 is a critical regulator of monocyte mobilization in hypertension and cardiac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a35f54f71bdef963c14978d8a76a419
https://doi.org/10.1161/hypertensionaha.120.14698
https://doi.org/10.1161/hypertensionaha.120.14698
Publikováno v:
Oxidative Medicine and Cellular Longevity.
Myocardial ischemia/reperfusion injury (I/RI) is closely associated with energy substrate metabolism. Fibronectin 1 (Fn1) was markedly elevated in the heart of I/R pigs and ischemic patients, but its role in myocardial I/RI is controversial and the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f93fe3ce9685d16ae19463ad2b35b0
Autor:
Yun-Long Zhang, Hui-Hua Li, Lei-Xin Zou, Xiao Han, Jiao Fang, Shu-Bin Guo, Hua-Jun Cao, Jie Yang, Xiao Yan, Pang-Bo Li, Hong-Xia Wang
Publikováno v:
Journal of Molecular and Cellular Cardiology. 137:34-45
Hypertensive cardiac remodeling is a major cause of heart failure. The immunoproteasome is an inducible form of the proteasome and its catalytic subunit β5i (also named LMP7) is involved in angiotensin II-induced atrial fibrillation; however, its ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973984a884b2f5e387b8ce5205f2cfe5
https://doi.org/10.1016/j.yjmcc.2019.09.010
https://doi.org/10.1016/j.yjmcc.2019.09.010
Publikováno v:
Journal of Cellular and Molecular Medicine
Atrial fibrillation (AF) is associated with inflammation and oxidative stress. Recently, we demonstrated that the chemokine‐receptor CXCR2 plays a critical role in the recruitment of monocytes/macrophages and the development of hypertension and car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206b0cbd24b59e06cadd4c9f25bc1a00
https://pubmed.ncbi.nlm.nih.gov/32812337
https://pubmed.ncbi.nlm.nih.gov/32812337
Publikováno v:
Hypertension research : official journal of the Japanese Society of Hypertension. 43(10)
Cardiac remodeling is an important pathological process ultimately leading to heart failure. Ubiquitin carboxy-terminal hydrolase 1 (UCHL1) is a deubiquitinase that plays a critical role in neurodegenerative diseases and cancer. However, its role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d52cdbde0672173c060a057ed534bb
https://pubmed.ncbi.nlm.nih.gov/32541849
https://pubmed.ncbi.nlm.nih.gov/32541849